Tag: week (page 2 of 19)

Jurassic World of Genetically Modified Simulacra

Jay Dyer, GuestJurassic World is the sometime sequel to whatever the last Jurassic film was. InJurassic Park, a ill-conceived theme park based on genetic resurrecting of the dinosaur all-star team. Now, Hollywood shows it’s gone fully green in recycling the same plot for a new audience of zombieswith Frankensaurus Rex. While the JurassicPlot (that’s a joke) is only a sliver different from the first, this time around genetic modifica [...]

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Raw Garlic Twice a Week Can Reduce Risk of Cancer by 40%

Marco Torres, Prevent DiseaseCompounds within garlic produce reactive oxygen species in cancer cells, activating of multiple death cascades and blocking pathways of tumor proliferation. Eating garlic just twice per week reduces cancer risk without any side effects whatsoever.The reason so many people die with conventional cancer treatment is that while damaging healthy cells, chemotherapy also triggers them to secrete a protein that sustains tumour growth and resistance to [...]

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These 4 Ingredients in Most Processed Foods are Decimating Your Health

Mae Chan, Prevent DiseaseIt’s not just the high fat, salt or sugar content of processed foods that is driving obesity and diet-related illnesses — the lack of food diversity is killing our gut flora, claims one researcher. If we exclude sugar, approximately 80 percent of all calories in processed foods come from a combination of four ingredients.Drawing upon evidence from multiple studies, Professor of genetic epidemiology at King’s College London and author of&nbsp [...]

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Why Do We Still Vaccinate? – 25 Questions From A Former Vaccine Advocate

Brian Rogers, Prevent DiseaseI used to be pro vaccine. I know the feeling of thinking others were just plain crazy and wrong for not vaccinating their children and themselves. ‘Irresponsible!’ I said when pointing my finger. I’d use the same old arguments about polio and small pox and how vaccines saved us from all those horrible diseases and just swallowing and regurgitating the propaganda I was brought up with. It was only recently, in 2009 that I started question [...]

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CRISPR-Cas9 modifies your DNA, under legal fire ~ Video




Excerpt from slashgear.com

A revolutionary method of editing the human genome has this week become the subject of a patent war. Back in April of 2014, patents were awarded by the USPTO (United States Patent and Trademark Office) to the Broad Institutes’ Dr. Feng Zhang, MIT, and Harvard to develop the technology behind "CRISPR-Cas9". 
This April, the UC Board of Regents’ legal team spoke with the USPTO about reconsidering their action, suggesting they award the patent to the inventor of the original method, UC Berkeley’s Jennifer Doudna. One way or another, this radical DNA modifier must be made. 

We need X-Men, after all.


The following video will explain what this genome-editing piece of technological breakthrough is all about. CRISPR-Cas9 is what it's called, and getting in to your body to make changes on a DNA level is what it's going for.

CRISPR-Cas9 works as a tiny scissors.

Utilizing the natural bacterial-level protective system used by your body to fight infections, CRISPR-Cas9 replicates the sequences of target DNA strands and latches on.

It's the connector that CRISPR-Cas9 makes real, and really programmable.

Your body provides the Cas9.* The Cas9 is the nuclease enzyme that cuts DNA strands.

*Correction - BACTERIA have Cas9, not our human selves. As helpful commenter "John" put so eloquently, "So far it has only been found in bacterial cells, and that's one of the things that makes it so amazing--a relatively simple molecular system that replicates many of the functions of our elaborate adaptive immune response, all in a single prokaryotic cell!"

Screen Shot 2015-05-15 at 10.11.42 AM
ABOVE: Image comes via Nature; Addgene, By Jonathan Corum, via NYT.

When a DNA sequence is cut, it may attempt to re-form. In doing so, it can create mutations.

But that's a discussion for another day.

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Genetically altered twin monkeys have been made using the CRISPR-Cas9 method. As you'll see in DOI: http://dx.doi.org/10.1016/j.cell.2014.01.027 in Cell Symposia "Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos", these monkeys are living large on gene-altered action.

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Today what's important is that two groups are fighting for the patents involved in CRISPR-Cas9.

A paper published online June 28 2012 by Science authored by Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A. Doudna, and Emmanuelle Charpentier describes the method: "A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity."

You can find this paper under code DOI: 10.1126/science.1225829.

Dr. Zhang suggests he demonstrated the CRISPR genome editing method before the 2012 paper was published by Dr. Doudna and Dr. Charpentier and crew. Dr. Doudna and Dr. Charpentier and crew suggest say Dr. Zhang's notebook (used as proof for patents) does not prove genome editing before the 2012 paper was published.

Can't we all just get along? Think of the monkeys!

Click to zoom

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Abandoned Uranium Mines Plague Navajo Nation

Sonia Luokkala, Earth Island JournalWaking TimesThe mesas of Monument Valley rise deep red on the horizon. We are in Diné Bikéyah, land of the Navajo.“This is John Wayne country,” trained Navajo guide Gregory Holiday repeats his lines for an enchanted group of tourists. The view opens boundless to the sacred land of the Diné people, but for visitors it is presented as the iconic west of cowboys and Americana.The sun sets and the last traveler boards t [...]

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Rare Quartet of Quasars Found in the Early Universe


This image shows a rare view of four quasars, indicated by white arrows, found together by astronomers using the Keck Observatory in Hawaii. The bright galactic nuclei are embedded in a giant nebula of cool, dense gas visible in the image as a blue haze. Hennawi & Arrigoni-Battaia, MPIA


Excerpt from smithsonian.com

The odds of success would make a Vegas bookie sit up and take notice. But in a one-in-10 million chance, astronomers surveying the sky have found a group of four tightly packed quasars in one of the most distant parts of the universe. The rare grouping may be a nascent galaxy cluster, and its unusually cold cradle of gas could prompt a re-think of how we model the early universe.

Quasars are among the brightest objects known—according to NASA, each one gives off more energy than 100 mature galaxies combined. But quasars are found only in the far reaches of the universe and can't be seen with the naked eye. Because of the time it takes light to travel that far, detecting such distant objects is akin to seeing back in time, so astronomers think quasars are the seeds of young galaxies, powered by gases falling into the supermassive black holes at their cores. As matter falls inward and gets close to the speed of light, it emits radiation that we can pick up with telescopes.

The quasar phase doesn't last long, only about a thousandth of a galaxy's lifetime. After that, the brightness dies down as the inflow of matter slows, says study leader Joseph Hennawi, an astrophysicist at the Max Planck Institute in Germany. Seeing any two quasars close together while they are still bright is a chancy business, so his team wasn't sure what they'd find when they set out to survey quasars using the W.M. Keck Observatory in Hawaii. To their surprise, they quickly pinpointed four of them in close proximity, cosmically speaking. The quartet is huddled up in an area of sky less than 600,000 light-years across that sits about 10 billion light-years from Earth.

"The authors found it by investigating the environment of just 29 bright quasars," says Michele Trenti, a senior lecturer at the University of Melbourne's School of Physics. "So at face value it seems like winning the lottery with a handful of tickets."
That's not all that was strange about this quasar quartet. The foursome was found inside a cloud of cold, dark gas, and the team's observations suggest that similar clouds surround about 10 percent of the tens of thousands of known quasars. That's odd, because according to current theories, quasars in groups like this should be surrounded by hot plasma, or ionized gas, at a temperature of about 10 million degrees.

“What this means is that there is some physical process that the models aren’t capturing,” says Hennawi, whose team reports the discovery this week in Science.



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Dying With Dignity

 Excerpt from huffingtonpost.comBy Debbie FinkCo-authored by Karen Bloch MorseThere is nothing easy or natural about watching your 41-year-old friend (of 41 years) -- who, by all counts, looks healthy -- ...

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Rats try to rescue others in distress, suggesting they feel empathy


Rats were even more likely to choose helping over getting a treat

Excerpt from cbc.ca

Calling someone a rat isn't a compliment about their character – but a new study suggests that maybe it should be.

Rats that see another rat struggling in a pool of water will open a door to rescue it, even if they could open a different door to get a chocolate treat instead.

Rats that knew what it was like to be wet and struggling in the pool were even quicker to help.
"Our findings suggest that rats can behave prosocially and that helper rats may be motivated by empathy-like feelings towards their distressed cage mate," Nobuya Sato, lead author of a study, said in a statement.

The study was published this week in the journal Animal Cognition.

Sato and his team at Kwansei Gakuin University in Japan designed experiments involving pairs of rat cage mates, either two males or two females.


'Helper rats may be motivated by empathy-like feelings,' suggests Nobuya Sato, a Kwansei Gakuin University in Japan research and lead author of a study released this week. (Andre Penner/Associated Press)


The two were placed in separate compartments separated by a transparent wall and door – one compartment that was dry and empty, and one filled with a deep pool of water and sheer walls that made it impossible to climb out. The door could be opened by the rat on the dry side, allowing the other rat to climb out of the pool.

Motivated by helping

Rats on the dry side of the cage were quick to open the door if they saw their cage mates struggling in the water, but not if the pool was empty or contained a stuffed toy rat. If no water was in either compartment, they also didn't open the door. That suggested that they were motivated by helping and not just opening the door for fun.

The researchers reversed the roles and found that rats were quicker to learn to open the door and rescue their cage mate if they had previously experienced a similar struggle in the pool.
"This modulation of learning by prior experience suggests that the helping behaviour observed in the present study might be based on empathy," they wrote.

In another experiment, rats in the dry compartment could choose between two different doors.
  • One that allowed them to rescue their cage mate from the pool.
  • Another that provided access to a chocolate cereal treat. 
More than half the time, rats chose to rescue the other rat first – especially if they were trained to open the door in a similar rescue scenario rather than being trained to open the door in order to access a food treat.

"These results suggest that for all rats, helping a distressed cage mate has a higher value than obtaining a food reward," the researchers wrote.

The results are similar to those in a previous experiment by different researchers, in which rats rescued other rats trapped in an acrylic tube. Still, there has some debate about whether this type of helping behaviour exists among animals other than primates such as monkeys and humans.

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Archaeologists Believe they have Found the Ruins of a Legendary Monastery



Excerpt from icelandreview.com

It is believed the remains of the much-searched-for Þykkvabær cloister may have been found. Icelandic and British archaeologists saw the remains of a very large building yesterday, using ultrasound techniques, at Álftaver in South Iceland.

The discovery came as a complete surprise, as it was not thought the remains of the cloister were in that area.

“I think we’ve just hit the jackpot, because I think we’ve discovered the remains of Þykkvabæjarklaustur. It came as a complete surprise, you can say that much. The remains are not on the site it was assumed the cloisters stood,” archaeology professor Steinunn Kristjánsdóttir told Stöð 2 television.

Þykkvabæjarklaustur, east of Mýrdalur, was a monastery of Augustine monks and its location has been lost to archaeologists until now. This week, ten Icelandic and British archaeologists have been searching for the remains with high tech instruments. The remains of an unusually big building were discovered under the ground yesterday, measuring around 40 x 45 meters.

“It is very big compared to the buildings of the time – as it is from the Middle Ages – and the footprint is around 1,500 square meters,” Steinunn says.

The cloister was in use from 1168 until 1550. Until recently it was assumed that Þykkvabæjarklaustur must have stood near the present-day Þykkvabæjarkirkja church, but searches revealed nothing; and this leads Steinunn to strongly believe yesterday’s find to be the lost cloisters. It is still possible, however, the remains are of a cow shed—but in that case it would be the cloister’s own cow shed and still therefore relevant.

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Circus Lion Freed From Cage Feels Earth Beneath His Paws For The First Time ~ Heartwrenching Video!




Will

Excerpt from thedodo.com
By Stephen Messenger

Footage shared this week by the Rancho dos Gnomos Santuário in Brazil shows the thrilling moment a lion named Will experiences, for the first time, the feeling of soil and grass beneath his feet.

Prior to being rescued and taken to the sanctuary, Will had been forced to perform with a traveling circus. For 13 long years, the lion had been confined to a cramped cage and denied any semblance of a normal existence. 

Within seconds of his release, Will can be seen eagerly running his paws through the soft soil — tragically, a foreign material for a creature who, up until then, had known only cold metal floors. 

Will's reaction to the grass that covers his sprawling new home is equally ecstatic. Despite his age, advanced for his species, the lion rolls around like a happy cub discovering life's simple pleasures. 

But perhaps the most touching part of Will's transition into his new sanctuary can be seen in this moment of repose, as if most impressed not by the feeling of dirt or grass, but by a newfound sense of peace. 

This scene, filmed in 2006 though released this week to the public, was only the beginning. In 2011, Will passed away of old age, but not before finally learning what it meant to be a lion. 

"He had five years of tranquility before he died. Here he had the opportunity to interact with other lions. He loved to lie in grass and look at the sky," sanctuary founder Marcos Pompeo told The Dodo. "He was a very happy lion."

Watch the video of Will's release in its entirety below:



  Click to zoom

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Mercury’s Mysterious Magnetic Past Goes Back 4 Billion Years

 Excerpt from sci-tech-today.com Examining rocks on Mercury's surface, scientists using data from NASA's Messenger spacecraft have revealed that the planet probably had a much stronger magnetic field nearly 4 billion years ago.  The fi...

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See Saturn moon’s ‘soda ocean’ shooting to surface in sheets

 Excerpt from  cnet.comEnceladus may have a warm ocean beneath its icy surface, but it may also be shooting through that crust in big sheets, perhaps filled with sea monkeys.       We already know that Saturn's ...

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