Tag: response (page 2 of 8)

Raw Garlic Twice a Week Can Reduce Risk of Cancer by 40%

Marco Torres, Prevent DiseaseCompounds within garlic produce reactive oxygen species in cancer cells, activating of multiple death cascades and blocking pathways of tumor proliferation. Eating garlic just twice per week reduces cancer risk without any side effects whatsoever.The reason so many people die with conventional cancer treatment is that while damaging healthy cells, chemotherapy also triggers them to secrete a protein that sustains tumour growth and resistance to [...]

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Pipeline Spill Dumps 105,000 Gallons of Oil on California’s Coastline

Oil from a broken pipeline coats miles of the Pacific Ocean and shoreline near Goleta, Calif., May 20, 2015, after a 24-inch underground pipeline broke May 19th and leaked into a culvert leading to the ocean. Houston-based Plains All American Pipeline said an thousands of gallons of oil were released before the pipeline was shut down. Photos by Jonathan Alcorn/Greenpeace. Steve Horn, DeSmog BlogUp to 105,000 gallons of oil obtained via offshore drilling have spilled from a p [...]

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Why Do We Still Vaccinate? – 25 Questions From A Former Vaccine Advocate

Brian Rogers, Prevent DiseaseI used to be pro vaccine. I know the feeling of thinking others were just plain crazy and wrong for not vaccinating their children and themselves. ‘Irresponsible!’ I said when pointing my finger. I’d use the same old arguments about polio and small pox and how vaccines saved us from all those horrible diseases and just swallowing and regurgitating the propaganda I was brought up with. It was only recently, in 2009 that I started question [...]

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Animal/Elemental Kingdoms/Agartha & a call to healers

Magenta Pixie"What happens to the pets and animals we love throughout our lifetime and that give so much love to us in return. Do they get to vibrate higher, and if they are micro chipped are their little animal souls safe? Do you know if they will be ok?"The Collective consciousness of Nine come forward with their response to this question. They also speak here of the Animal & Elemental Kingdoms & their part in Ascension. They respond to the question asked about the Hollow Earth theory [...]

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CRISPR-Cas9 modifies your DNA, under legal fire ~ Video




Excerpt from slashgear.com

A revolutionary method of editing the human genome has this week become the subject of a patent war. Back in April of 2014, patents were awarded by the USPTO (United States Patent and Trademark Office) to the Broad Institutes’ Dr. Feng Zhang, MIT, and Harvard to develop the technology behind "CRISPR-Cas9". 
This April, the UC Board of Regents’ legal team spoke with the USPTO about reconsidering their action, suggesting they award the patent to the inventor of the original method, UC Berkeley’s Jennifer Doudna. One way or another, this radical DNA modifier must be made. 

We need X-Men, after all.


The following video will explain what this genome-editing piece of technological breakthrough is all about. CRISPR-Cas9 is what it's called, and getting in to your body to make changes on a DNA level is what it's going for.

CRISPR-Cas9 works as a tiny scissors.

Utilizing the natural bacterial-level protective system used by your body to fight infections, CRISPR-Cas9 replicates the sequences of target DNA strands and latches on.

It's the connector that CRISPR-Cas9 makes real, and really programmable.

Your body provides the Cas9.* The Cas9 is the nuclease enzyme that cuts DNA strands.

*Correction - BACTERIA have Cas9, not our human selves. As helpful commenter "John" put so eloquently, "So far it has only been found in bacterial cells, and that's one of the things that makes it so amazing--a relatively simple molecular system that replicates many of the functions of our elaborate adaptive immune response, all in a single prokaryotic cell!"

Screen Shot 2015-05-15 at 10.11.42 AM
ABOVE: Image comes via Nature; Addgene, By Jonathan Corum, via NYT.

When a DNA sequence is cut, it may attempt to re-form. In doing so, it can create mutations.

But that's a discussion for another day.

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Genetically altered twin monkeys have been made using the CRISPR-Cas9 method. As you'll see in DOI: http://dx.doi.org/10.1016/j.cell.2014.01.027 in Cell Symposia "Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos", these monkeys are living large on gene-altered action.

12DOUDNAjp-articleLarge

Today what's important is that two groups are fighting for the patents involved in CRISPR-Cas9.

A paper published online June 28 2012 by Science authored by Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A. Doudna, and Emmanuelle Charpentier describes the method: "A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity."

You can find this paper under code DOI: 10.1126/science.1225829.

Dr. Zhang suggests he demonstrated the CRISPR genome editing method before the 2012 paper was published by Dr. Doudna and Dr. Charpentier and crew. Dr. Doudna and Dr. Charpentier and crew suggest say Dr. Zhang's notebook (used as proof for patents) does not prove genome editing before the 2012 paper was published.

Can't we all just get along? Think of the monkeys!

Click to zoom

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Science: Plants Have Senses and Can Hear, Feel and Identify Attackers

Alisa Opar, GuestThe plant world is a violent place. When munching caterpillars or grazing cattle set their sights on a luscious leaf, a plant can’t hightail it out of harm’s way. Instead, flora fight back with noxious chemicals. But what repels one critter may not work on the next hungry mouth, explains Heidi Appel, a senior research scientist in the Bond Life Sciences Center at the University of Missouri. She’s found that some plants can actual [...]

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11 Common Symptoms of the Global Depopulation Slow Kill

Sigmund Fraud, Staff Writer“Maintain humanity under 500,000,000 in perpetual balance with nature.” – The Georgia GuidestonesThe full-spectrum global attack on human health is quite obvious to see for anyone who is paying attention and in search of wellness. So many of the factors that are negatively influencing public heath could easily be prevented or removed from society, yet the decisions of the ruling class continue to ensure that our food supply [...]

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10 Ways to Salvage a Bad Morning Before Parting Ways

Excerpt from huffingtonpost.com1. Notice the good -- any and all good you can find -- even if it is simply, "I am so glad to see your face this morning," or, "You've always had a knack for unique clothing combinations!" 2. If someone is grumpy,...

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Lab for genetic modification of human embryos just $2,000 away – report


Reuters / Christian Charisius



Reuters

With the right expertise in molecular biology, one could start a basic laboratory to modify human embryos using a genome-editing computer technique all for a couple thousand dollars, according to a new report.

Genetic modification has received heightened scrutiny recently following last week’s announcement that Chinese researchers had, for the first time, successfully edited human embryos’ genomes. 
The team at Sun Yat-Sen University in Guangzhou, China, used CRISPR (clustered regularly interspaced palindromic repeats), a technique that relies on “cellular machinery” used by bacteria in defense against viruses. 

This machinery is copied and altered to create specific gene-editing complexes, which include the wonder enzyme Cas9. The enzyme works its way into the DNA and can be used to alter the molecule from the inside. The combination is attached to an RNA guide that takes the gene-editing complex to its target, telling Cas9 where to operate. 

Use of the CRISPR technique is not necessarily relegated to the likes of cash-flush university research operations, according to a report by Business Insider. 


Geneticist George Church, who runs a top CRISPR research program at the Harvard Medical School, said the technique could be employed with expert knowledge and about half of the money needed to pay for an average annual federal healthcare plan in 2014 -- not to mention access to human embryos. 

"You could conceivably set up a CRISPR lab for $2,000,” he said, according to Business Insider. 

Other top researchers have echoed this sentiment. 

"Any scientist with molecular biology skills and knowledge of how to work with [embryos] is going to be able to do this,” Jennifer Doudna, a biologist at the University of California, Berkeley, recently told MIT Tech Review, which reported that Doudna co-discovered how to edit genetic code using CRISPR in 2012. 

Last week, the Sun Yat-Sen University research team said it attempted to cure a gene defect that causes beta-thalassemia (a genetic blood disorder that could lead to severe anemia, poor growth, skeletal abnormalities and even death) by editing the germ line. For that purpose they used a gene-editing technique based on injecting non-viable embryos with a complex, which consists of a protective DNA element obtained from bacteria and a specific protein. 

"I suspect this week will go down as a pivotal moment in the history of medicine," wrote science journalist Carl Zimmer for National Geographic.


Response to the new research has been mixed. Some experts say the gene editing could help defeat genetic diseases even before birth. Others expressed concern. 

“At present, the potential safety and efficacy issues arising from the use of this technology must be thoroughly investigated and understood before any attempts at human engineering are sanctioned, if ever, for clinical testing,” a group of scientists, including some who had worked to develop CRISPR, warned in Science magazine. 

Meanwhile, the director of the US National Institutes for Health (NIH) said the agency would not fund such editing of human embryo genes. 

“Research using genomic editing technologies can and are being funded by NIH,” Francis Collins said Wednesday. “However, NIH will not fund any use of gene-editing technologies in human embryos. The concept of altering the human germline in embryos for clinical purposes ... has been viewed almost universally as a line that should not be crossed.”

Although the discovery of CRISPR sequences dates back to 1987 – when it was first used to cure bacteria of viruses – its successes in higher animals and humans were only achieved in 2012-13, when scientists achieved a revolution by combining the resulting treatment system with Cas9 for the first time. 


On April 17, the MIT’s Broad Institute announced that has been awarded the first-ever patent for working with the Crisp-Cas9 system. 

The institute’s director, Eric Lander, sees the combination as “an extraordinary, powerful tool. The ability to edit a genome makes it possible to discover the biological mechanisms underlying human biology.”

The system’s advantage over other methods is in that it can also target several genes at the same time, working its way through tens of thousands of so-called 'guide' RNA sequences that lead them to the weapon to its DNA targets. 

Meanwhile, last month in the UK, a healthy baby was born from an embryo screened for genetic diseases, using karyomapping, a breakthrough testing method that allows doctors to identify about 60 debilitating hereditary disorders.

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UFO Crash in Canada? No says military Canadian Forces

 Posts like these were circulating on Twitter and Facebook on Wednesday night, with people suggesting there was a UFO crash near Jackhead, Man. It was actually an airplane being used in a military training exercise, according to the Canadian Forces.



Excerpt from cbc.ca

Social media reports of a possible UFO sighting last night near Jackhead, Man., are not true, says the Canadian Forces, which attributed the bright light people saw to an airplane from a training exercise.

On Wednesday night (Feb 18th, 2015), several people said on Twitter and Facebook that they saw a bright light in the sky, fuelling speculation that it may have been an unidentified flying object.

The rumour became stronger when photos were posted of Canadian Forces vehicles in the area, with some people claiming the military was there to contain a UFO crash site.

But it was not a UFO at all, says Lt.-Col. Paul Davies, commanding officer 38 Territorial Battalion Group, which is involved in an Arctic Response Company Group training exercise on Lake Winnipeg this week.

Exercise Arctic Bison 2015
Members of the Arctic Response Company Group drive across frozen Lake Winnipeg during Exercise Arctic Bison 2015. (MCpl Cameron Skrypnyk/DND)


"There's no aliens, just my friends in the air force who are out there helping us on this exercise," Davies told CBC News on Thursday.
"I have the commander of that air force contingent sitting right beside me and, you know, he assures us that that was not a UFO, but that was him."

About 150 military personnel are taking part in Exercise Arctic Bison 2015, which includes the 38 Canadian Brigade Group, the 2nd Battalion of the Princess Patricia’s Canadian Light Infantry, the 4th Canadian Ranger Patrol Group, and 440 Squadron of the Royal Canadian Air Force.

Davies said soldiers are training to deal with a plane crash and provide ground search and rescue support in the Arctic.

The bright light that people saw, he explained, came from an airplane that takes off very quickly.

"From a distance it may have looked like it was going straight up in the air, but it wasn't," he said. "It was just us out there playing our games."

The exercise wraps up on Sunday.

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Don’t Blame the Devil Anymore: Is Temptation All in Your ‘Syn’ apse?

 I find it very interesting that 'temptation' may lie within the 'syn' - apse. Greg Excerpt from huffingtonpost.comLack of self-control is at the root of many personal and social ills, from alcoholism to obesity. Even when we are well aware ...

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Earth To Aliens: Scientists Want To Send Messages To Extraterrestrial Intelligence Possibly Living On Exoplanets

Excerpt from techtimes.comExtraterrestrial research experts have said that now is the time to contact intelligent life on alien worlds.Leading figures behind the Search for Extraterrestrial Intelligence (Seti), which has been using radio telescop...

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New internet neutrality: FCC chairman proposes strong new rules

Excerpt from mercurynews.comThe federal government's top communications regulator on Wednesday called for strong new rules to bar Internet and wireless providers from blocking, slowing or discriminating against consumers' access to particular websi...

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