Tag: purposes (page 2 of 5)

Lab for genetic modification of human embryos just $2,000 away – report


Reuters / Christian Charisius



Reuters

With the right expertise in molecular biology, one could start a basic laboratory to modify human embryos using a genome-editing computer technique all for a couple thousand dollars, according to a new report.

Genetic modification has received heightened scrutiny recently following last week’s announcement that Chinese researchers had, for the first time, successfully edited human embryos’ genomes. 
The team at Sun Yat-Sen University in Guangzhou, China, used CRISPR (clustered regularly interspaced palindromic repeats), a technique that relies on “cellular machinery” used by bacteria in defense against viruses. 

This machinery is copied and altered to create specific gene-editing complexes, which include the wonder enzyme Cas9. The enzyme works its way into the DNA and can be used to alter the molecule from the inside. The combination is attached to an RNA guide that takes the gene-editing complex to its target, telling Cas9 where to operate. 

Use of the CRISPR technique is not necessarily relegated to the likes of cash-flush university research operations, according to a report by Business Insider. 


Geneticist George Church, who runs a top CRISPR research program at the Harvard Medical School, said the technique could be employed with expert knowledge and about half of the money needed to pay for an average annual federal healthcare plan in 2014 -- not to mention access to human embryos. 

"You could conceivably set up a CRISPR lab for $2,000,” he said, according to Business Insider. 

Other top researchers have echoed this sentiment. 

"Any scientist with molecular biology skills and knowledge of how to work with [embryos] is going to be able to do this,” Jennifer Doudna, a biologist at the University of California, Berkeley, recently told MIT Tech Review, which reported that Doudna co-discovered how to edit genetic code using CRISPR in 2012. 

Last week, the Sun Yat-Sen University research team said it attempted to cure a gene defect that causes beta-thalassemia (a genetic blood disorder that could lead to severe anemia, poor growth, skeletal abnormalities and even death) by editing the germ line. For that purpose they used a gene-editing technique based on injecting non-viable embryos with a complex, which consists of a protective DNA element obtained from bacteria and a specific protein. 

"I suspect this week will go down as a pivotal moment in the history of medicine," wrote science journalist Carl Zimmer for National Geographic.


Response to the new research has been mixed. Some experts say the gene editing could help defeat genetic diseases even before birth. Others expressed concern. 

“At present, the potential safety and efficacy issues arising from the use of this technology must be thoroughly investigated and understood before any attempts at human engineering are sanctioned, if ever, for clinical testing,” a group of scientists, including some who had worked to develop CRISPR, warned in Science magazine. 

Meanwhile, the director of the US National Institutes for Health (NIH) said the agency would not fund such editing of human embryo genes. 

“Research using genomic editing technologies can and are being funded by NIH,” Francis Collins said Wednesday. “However, NIH will not fund any use of gene-editing technologies in human embryos. The concept of altering the human germline in embryos for clinical purposes ... has been viewed almost universally as a line that should not be crossed.”

Although the discovery of CRISPR sequences dates back to 1987 – when it was first used to cure bacteria of viruses – its successes in higher animals and humans were only achieved in 2012-13, when scientists achieved a revolution by combining the resulting treatment system with Cas9 for the first time. 


On April 17, the MIT’s Broad Institute announced that has been awarded the first-ever patent for working with the Crisp-Cas9 system. 

The institute’s director, Eric Lander, sees the combination as “an extraordinary, powerful tool. The ability to edit a genome makes it possible to discover the biological mechanisms underlying human biology.”

The system’s advantage over other methods is in that it can also target several genes at the same time, working its way through tens of thousands of so-called 'guide' RNA sequences that lead them to the weapon to its DNA targets. 

Meanwhile, last month in the UK, a healthy baby was born from an embryo screened for genetic diseases, using karyomapping, a breakthrough testing method that allows doctors to identify about 60 debilitating hereditary disorders.

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Top Secret Government Programs That Your Not Supposed To Know About

Originally Posted at in5d.com The following is the alleged result of the actions of one or more scientists creating a covert, unauthorized notebook documenting their involvement with an Above Top Secret government program. Government publications and information obtained by the use of public tax monies cannot be subject to copyright. This document is released into the public domain for all citizens of the United States of America. THE ‘MAJIC PROJECTS’ SIGMA is the project whic [...]

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Is Titan submarine the most daring space mission yet?

The submersible could extract cores from the seabed to unlock a rich climatic historyExcerpt from bbc.comDropping a robotic lander on to the surface of a comet was arguably one of the most audacious space achievements of recent times. But one...

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Rare doomed planet with extreme seasons discovered


Kepler432b.jpg
Illustration provided by the University of Heidelberg of the orbit of Kepler-432b (inner, red) in comparison to the orbit of Mercury around the Sun (outer, orange). The red dot in the middle indicates the position of the star around which the planet is orbiting. The size of the star is shown to scale, while the size of the planet has been magnified ten times for illustration purposes. (Graphic: Dr. Sabine Reffert)


Excerpt from foxnews.com/science


A rare planet has been discovered, and it doesn’t seem like a stop anyone would want to make on an intergalactic cruise. Found by two research teams independently of each other, Kepler-432b is extreme in its mass, density, and weather. Roughly the same size of Jupiter, the planet is also doomed- in 200 million years it will be consumed by its sun. “Kepler-432b is definitively a rarity among exoplanets around giant stars: it is a close-in gas-giant planet orbiting a star whose radius is 'quickly' increasing,” Davide Gandolfi, from the Landessternwarte Koenigstuhl (part of the Centre for Astronomy of the University of Heidelberg), told FoxNews.com. “The orbit of the planet has a radius of about 45 million kilometers [28 million miles] (as a reference point, the Earth-Sun distance is about 150 million kilometers [93.2 Million miles]), while most of the planets known to orbit giant stars have wider orbits. The stellar radius is already 3 million kilometers [almost 2 million miles] (i.e., about 4 times the Sun radius) and in less than 200 million years it will be large enough for the star to swallow up its planet.”

Gandolfi, a member of one of the research groups who discovered the rare planet, explains that much like Jupiter, Kepler-432b is a gas-giant celestial body composed mostly of hydrogen and helium, and is most likely to have a dense core that accounts for 6 percent or less of the planet’s mass. “The planet has a mass six times that of Jupiter, but is about the same size!” he says. “This means that it is not one of the largest planets yet discovered: it is one of the most massive!” The planet’s orbit brings it extremely close to its host star on some occasions, and very far away at others, which creates extreme seasonal changes. In its year - which lasts 52 Earth days - winters can get a little chilly and summers a bit balmy, to say the least. According to Gandolfi, “The highly eccentric orbit brings Kepler-432b at ‘only’ 24 million kilometers [15 million miles] from its host star, before taking it to about three times as far away. This creates large temperature excursions over the course of the planet year, which is of only 52 Earth days. During the winter season, the temperature on Kepler-432b drops down to 500 degrees Celsius [932 degrees Fahrenheit], whereas in summer it can goes up to nearly 1000 degrees Celsius [1832 degrees Fahrenheit].”

Then again, if you are crazy enough to visit Kepler-432b, you’d better do it fast. As stated before, its host star is set to swallow the planet whole in 200 million years, making the celestial body a rare find. “The paucity of close-in planets around giant stars is likely to be due to the fact that these planets have been already swallowed up by their host stars,” Gandolfi says. “Kepler-432b has been discovered ‘just in time before dinner!” The host star, which is red and possesses 1.35 times the mass of our sun, has partly exhausted the nuclear fuel in its core, and is slowly expanding, eventually growing large enough to swallow Kepler-432b. According to Gandolfi, this is a natural progression for all stars. “Stars first generate nuclear energy in their core via the fusion of Hydrogen into Helium,” he explained. “At this stage, their radii basically do not change much. This is because the outward thermal pressure produced by the nuclear fusion in the core is balanced by the inward pressure of gravitational collapse from the overlying layers. In other words, the nuclear power is the star pillar! Our Sun is currently ‘burning’ hydrogen in its core (please note that I used quotes: ‘burning’ does not mean a chemical reaction- we are talking about nuclear fusion reaction). However, this equilibrium between the two pressures does not last forever. Helium is heavier than hydrogen and tends to sink. The stellar core of the Kepler-432b's host star is currently depleted of hydrogen and it is mainly made of inert helium. The star generates thermal energy in a shell around the core through the nuclear fusion of hydrogen into helium. As a result of this, the star expands and cools down. This is why we call it ‘red giant’- the reddish color comes from the fact that the external layers of the atmosphere of the star are cooling down because they expand.”

Both research teams (the other was from the Max Planck Institute for Astronomy in Heidelberg) used Calar Alto Observatory’s 7.2- foot telescope in Andalucia, Spain. The planet was also studied by Landessternwarte Koenigstuhl researchers using the 8.5-foot Nordic Optical Telescope on La Palma, which is located in Spain’s Canary Islands.

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Sacred Knowledge of Vibration and Power of Human Emotions

WHAT IS THE UNIVERSAL TRUTH?

Why has this universal truth been hidden from the beings on this planet?

This is the biggest mystery. For over 25,000 years the Universal Truth was not available to the people of this planetary system. It is now finally being received on this planet. Deep seekers of the truth that are open minded and ready will receive it.

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Aliens Even More Likely Now To Be Out There ~ Average star has two potentially Earth-like worlds



Concept art depicting the lights of an ET civilisation on an exoplanet. Credit: David A Aguilar (CfA)

Excerpt from theregister.co.uk



Boffins in Australia have applied a hundreds-of-years-old astronomical rule to data from the Kepler planet-hunting space telescope. They've come to the conclusion that the average star in our galaxy has not one but two Earth-size planets in its "goldilocks" zone where liquid water - and thus, life along Earthly lines - could exist.

“The ingredients for life are plentiful, and we now know that habitable environments are plentiful,” says Professor Charley Lineweaver, a down-under astrophysicist.

Lineweaver and PhD student Tim Bovaird worked this out by reviewing the data on exoplanets discovered by the famed Kepler planet-hunter space scope. Kepler naturally tends to find exoplanets which orbit close to their parent suns, as it detects them by the changes in light they make by passing in front of the star. As a result, most Kepler exoplanets are too hot for liquid water to be present on their surfaces, which makes them comparatively boring.
Good planets in the "goldilocks" zone which is neither too hot nor too cold are much harder to detect with Kepler, which is a shame as these are the planets which might be home to alien life - or alternatively, home one day to transplanted Earth life including human colonists, once we've cracked that pesky interstellar travel problem.

However there exists a thing called the Titius-Bode relation - aka Bode's Law - which can be used, once you know where some inner planets are, to predict where ones further out will be found.

Assuming Bode's Law works for other suns as it does here, and inputting the positions of known inner exoplanets found by Kepler, Lineweaver and Bovaird found that on average a star in our galaxy has two planets in its potentially-habitable zone.

That doesn't mean there are habitable or inhabited planets at every star, of course. Even here in our solar system, apparently lifeless (and not very habitable) Mars is in the habitable zone.

Even so, there are an awful lot of planets in the galaxy, so some at least ought to have life on them, and in some cases this life ought to have achieved a detectable civilisation. Prof Lineweaver admits that the total lack of any sign of this is a bit of a puzzler.

"The universe is not teeming with aliens with human-like intelligence that can build radio telescopes and space ships," admits the prof. "Otherwise we would have seen or heard from them.
“It could be that there is some other bottleneck for the emergence of life that we haven’t worked out yet. Or intelligent civilisations evolve, but then self-destruct.”

Of course, humans - some approximations of which have been around for some hundreds of thousands of years, perhaps - have only had civilisation of any kind in any location for a few thousand of those years. Our civilisation has only risen to levels where it could be detectable across interstellar distances very recently.

There may be many planets out there inhabited by intelligent aliens who either have no civilisation at all, or only primitive civilisation. There may be quite a few who have reached or passed the stage of emitting noticeable amounts of radio or other telltale signs, but those emissions either will not reach us for hundreds of thousands of years - or went past long ago.

It would seem reasonable to suspect that there are multitudes of worlds out there where life exists in plenty but has never become intelligent, as Earth life was for millions of years before early humans began using tools really quite recently.

But the numbers are still such that the apparent absence of star-travelling aliens could make you worry about the viability of technological civilisation if, like Professor Lineweaver, you learn your astrophysics out of textbooks and lectures (and publish your research, as we see here, in hefty boffinry journals like the Monthly Notices of the Royal Astronomical Society).

But if movies, speculofictive novels and TV have taught us anything here on the Reg alien life desk, it is that in fact the galaxy is swarming with star-travelling aliens (and/or humans taken secretly from planet Earth for mysterious purposes in the past, or perhaps humans from somewhere else etc). The reason we don't know about them is that they don't want us to.

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10 Mysterious Biblical Figures No One Can Explain






listverse.com

The canonical Bible is filled with mysterious characters, many of whom drop in for a cameo, do their thing, and then slide out, never to be heard from again. Some are merely extras, but some have a contextual presence that begs further examination. And some are, well, just weird.

10  Melchizedek

01
 

Probably the single most mysterious figure in the Bible, Melchizedek was a priest-king of Salem (later known as Jerusalem) in the time of Abram (Abraham), suggesting a religious organization, complete with ritual and hierarchy, that predated the Jewish nation and their priestly lineage from the tribe of Levi. He is only portrayed as active in one passage, although he is alluded to once in Psalms, and several times in the New Testament’s Epistle to the Hebrews.
Some Jewish disciplines insist that Melchizedek was Shem, Noah’s son. He is thought of, in Christian circles, as a proto-messiah, embodying certain traits later given to Christ. New Testament writings assert that Christ was “a priest forever in the order of Melchizedek,” indicating an older and deeper covenant with God than the Abrahamic-Levite lineage.
Hebrews 7, though presents him in a more unusual light. In verses 3 and 4:
“Without father, without mother, without descent, having neither beginning of days, nor end of life; but made like unto the Son of God; abideth a priest continually. Now consider how great this man was, unto whom even the patriarch Abraham gave the tenth of the spoils.”
Not only do these verses grant Melchizedek a hierarchical level above the most important Jewish patriarch, they assign him mystical qualities. Some take this to mean an earlier incarnation of Christ. Others see it as an ancient manifestation of the Holy Spirit. His identity, role, and theological function have long been debated.
The paucity of scriptural references have added to the mystery, making him a somewhat spectral figure. As such, newer spiritual traditions, as well as New Age quacks, have taken liberties with his persona. Gnostics insisted he became Jesus, and he is cited as a high-level priest in Masonic and Rosicrucian lore. Joseph Smith wrote that he was the greatest of all prophets, and Mormons still trace their priesthood back to him. The Urantia, a 20th-century pseudo-Bible that claims to merge religion, philosophy, and science, insists he’s the first in an evolutionary succession of deification manifestations, with Abraham being his first convert.
There is even a school of thought that Melchizedek is a title or assumed character name, sort of a theological 007, played by a series of Judeo-Christian James Bonds. 

The lore of Melchizedek is confusing but deep and fascinating. Apocryphal books give us more details, some cryptic, some relatively mundane. The Second Book of Enoch is particularly informative, insisting Melchizedek was born of a Virgin. When his mother Sophonim (the wife of Noah’s brother Nir) died in childbirth, he sat up, clothed himself, and sat beside her corpse, praying and preaching. After 40 days, he was taken by an archangel to the Garden of Eden, protected by angels and avoiding the Great Flood without passage on Uncle Noah’s ark.

9  Cain’s Wife

02
 

Cain was, according to Genesis, the first human ever born. He later killed his younger brother Abel in a hissy fit over his sacrifice of meat being more favored than Cain’s sacrificial fruit basket. God put a mark on Cain and cursed the ground he farmed, forcing him into a life as a wandering fugitive. 

That part of the story is fairly well known. Later, though, we read that he settled in the Land of Nod, and, all of a sudden, he has a wife. Absolutely nothing else is mentioned about her. We don’t even know where she came from. In fact, the question of where Cain got his wife, when his immediate family were apparently the only people in the world, has sent many a perceptive young Sunday schooler down the road of skepticism. 

Some have posited a mysterious other tribe of people, maybe created after Adam and Eve, maybe even another race or species. But the standard response is that Adam and Eve had many other sons and daughters to populate the Earth. The only way to keep the human race going would be to mate with siblings, nieces, nephews, and cousins. 

In fact, though the Holy Bible is silent on her identity, the apocryphal Book of Jubilees tells us exactly who was Cain’s wife: his sister Awan, who bore his son Enoch.

8  Joseph Barsabbas

03
 

After Judas Iscariot turned in his resignation by selling out his boss, Jesus’s disciples rushed to fill the open position and bring the number back up to a more theologically apt 12. The remaining disciples, including the newly convinced Thomas, looked over the candidates from the 120 or so adherents who followed Jesus. Then they cast lots to pick who would fill the position. 

It went to Matthias, a fairly mysterious character himself. We don’t know where he came from or his previous occupation. Some think he was actually the diminutive Zacchaeus, the tax collector who climbed a sycamore tree to get a better glimpse of Jesus’s ride on the donkey.
The man who lost out was Joseph Barsabbas, also known as Joseph Justus. We know nothing solid about him, even less than we know about Matthias.
There is, however, one bit of interesting speculation. A list of names presented in Mark 6:3 includes some of Christ’s earliest and most loyal adherents. One of these is a man named Joses, and another is James the Just. Biblical scholar Robert Eisenman suggests that James carried on Jesus’s work, and the writer of the Book of Acts assigned him an alias to minimize his importance.

7  The Beloved Disciple

04
 

In the Gospel of John, several references are made to “the disciple whom Jesus loved.” This particular favorite is present at the Last Supper, the crucifixion, and after the resurrection. The writer of the Gospel of John even states that the testimony of this disciple is the basis for the text. But there is considerable debate over the identity of this mystery figure.
The most obvious nominee is John the Apostle, one of Christ’s inner circle of 12 and the namesake of the Gospel. But none of the 12 apostles were present at the crucifixion, so that crosses him off the list. Lazarus, resurrected by Christ, is also considered. He seems to have been present at the cited events and is referred to specifically, in the story of His death and resurrection, as “he whom Thou lovest.”
Mary Magdalene, Judas, Jesus’s brother James, or an unnamed disciple, possibly even a Roman or governmental official, have all been considered. There is even a school of thought that John is an interactive gospel, with the reader being the beloved disciple.

6  Simon Magus

05
 

“Simony” is the selling of church position or privilege. It is named for Simon Magus, or Simon the Magician, who makes only a brief appearance in the Bible, in Acts 8:9–24. Simon has since become synonymous with heretical thought, and religious exploitation.
He is presented as a powerful magician with a large following of in Samaria, who converts to Christianity and wishes to learn from apostles Peter and Phillip. When he sees the gifts of the Holy Spirit, including speaking in tongues and an ecstatic spiritual state, he offers the men money if they will give him the secret to passing these gifts to others. They are not amused.
Apocryphal texts reveal quite a bit more, like his alleged ability to levitate and even fly, emphasizing that he was something akin to a cult leader in his hometown. It is suggested that his conversion is more for economic purposes than spiritual, and he set himself up as a messianic figure himself, competing for the Jesus dollar with his own homespun theology.
He is thought by some to be a founder of Gnosticism, a patchwork of various religious systems that relied heavily on Judaic and Christian symbolism.

5  Onan

06
 

Not unlike Simon Magus, Onan’s brief appearance inspired a name for a particular action.
He was the second son of Abraham’s grandson Judah, the patriarch and namesake of one of the 12 tribes of Israel. His older brother, Er (yes, just “Er”) was “wicked in the sight of the Lord,” so God killed him. What he did to deserve such an execution remains a mystery.
Tradition at the time dictated that Er’s widow, Tamar, become Onan’s wife. Onan had to impregnate her to keep the lineage alive, but he was not as wild about the idea. Maybe it was the thought of impending fatherhood, or Tamar just wasn’t his type. So, taking matters into his own hands, he committed the first recorded act of coitus interruptus. Or, as Genesis 38:9 so poetically put it: “And Onan knew that the seed should not be his; and it came to pass, when he went in unto his brother’s wife, that he spilled it on the ground, lest that he should give seed to his brother.” God was displeased and slew Onan.
The whole tale gets even more sordid. Onan had a younger brother, Shelah. Customarily, he would have been next in line to impregnate Tamar, but Judah forbade it. Tamar, rather than graciously accepting forced spinsterhood, seduced Judah and (became pregnant) by the old man. Judah fathered twins Zerah and Perez, the latter of whom was listed by Matthew as an ancestor of Jesus’s earthly father Joseph...
Some have even suggested that Onan’s death warns that sex is meant only for purposes of reproduction, and not for pleasure.

4  Nicodemus

07
 

Nicodemus was a member of the Sanhedrin, a council of men who ruled on Jewish law and governance. He became a friend, follower, and intellectual foil for Jesus, whose egalitarian teachings often ran counter to the Sanhedrin’s rigid decrees. He was also a Pharisee, a leader within the Jewish community who toadied up to the Roman government at the time of Christ’s arrest and subsequent crucifixion.
He is mentioned three times in the New Testament, all in the Gospel of John. He subtly defends Jesus as the Pharisees discuss His impending arrest. Later, he helps prepare Jesus’s body for burial, indicating he had become an adherent to Christ and His teachings.
The first time he is mentioned, however, is in dialogue with Jesus, and these conversations reveal some of the most important aspects of Christian theology, such as the notion of being “born again” and the most famous reference to the divinity of Christ, John 3:16: “For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him should not perish, but have everlasting life.”
This detailed conversation explores the divide between the Old Covenant’s dogmatic and exclusive Jewish Law and the New Covenant’s spiritually inclusive concepts. But for a vital contributor to such an important passage of the New Testament, Nicodemus remains a mysterious figure. Some scholars have suggested he may be Nicodemus ben Gurion, a Talmudic figure of wealth and mystical power. Christian tradition suggest he was martyred, and he is venerated as a saint. His name has come to be synonymous with seekers of the truth and is used as a character in many works of biblically inspired fiction.

3  James The Just

08
 

He is considered, next to Paul and Peter, the most important apostolic figure in the Church’s history. The Book of Acts specifically names him the head of the Christian church in Jerusalem, and he is frequently cited, both scripturally and apocryphally, as being consulted by both Paul and Peter. So who is he?
Traditionally, he is thought of as Jesus’s brother (or, more precisely, His half-brother). Jesus is listed, in the Gospels, as having siblings, some younger than Him. One was named James.
But James was a common name, and there are several mentioned in the Bible. Two of the 12 disciples were named James, but both are listed as having different fathers than Jesus, and neither went on to become James the Just. James the son of Zebedee went on to be known as James the Great, and James the son of Alphaeus was called James the Less.
It is known that he was a contemporary of Jesus, although he seems to have had no real inner-circle status during Christ’s ministry. The apocryphal Gospel of Thomas says Christ Himself designated James to lead the movement upon His death. The Apostle Paul initially seems respectful, even subservient, to “James the Lord’s brother,” calling him a “pillar” of the movement, even though he was later to disagree with him on matters of doctrine.
Some, though, have suggested the “brother” designation was spiritual, rather than physical. St. Jerome, among others, suggested that the doctrine of perpetual virginity indicated James could be a cousin, which, given the tribal associations and clannishness of the Jewish community of the time, seems valid. Such a relationship would indicate a certain social proximity without necessarily being a true sibling.

2  Simon The Zealot

09
 

Of Christ’s 12 disciples, none are more mysterious than Simon the Zealot. His name was meant to differentiate him from Simon Peter and has come to symbolize, for some, that he was a member of a similarly named political movement that advocated Jewish defiance to Roman law. Some have speculated that he acted, within Christ’s inner circle, as a political adviser. His presence then indicated that Jesus had a revolutionary political agenda.
The truth is much less exciting. The “Zealot” movement did not take place until long after the time that Christ would have given Simon his sobriquet, and there has never been any serious evidence that Simon, despite the designation, was a political radical. The name, and the word upon which it is based, did not take on those aggressive undertones until the movement itself was in full swing. More than likely, Simon was given his name because of intense spiritual devotion, rather than any radical political stance.
Nothing else is known of him, at least not with any surety. The Catholic Encyclopedia mentions him as possibly being a brother or cousin of Jesus, with no real evidence. The Eastern Orthodox tradition says he developed his zeal when Jesus attended his wedding and changed water into wine. Some legends say he was martyred; the philosopher Justus Lipsius somehow got it into his head that he was sawed in half.

1  Og

10
 

Cited twice specifically, but alluded to frequently in general terms, the Nephilim were a race of violent giants that lived in the pre-Flood world at the same time as humanity. Were they, as some suggest, the offspring of demons and human women? Fallen angels themselves? Or simply the descendants of Seth mentioned in the Dead Sea scrolls, a tribe of cranky cases cursed by God for their rebelliousness? Regardless, they evolved and became known by other names, like the Raphaim, and frequently battled humans for land and power.
The most storied of them was Og, the King of Bashan. He was killed, along with his entire army, and his kingdom was ransacked. All of the survivors—men, women, and children—were put to death, and the strongest and most powerful line of Nephilim descendants was eliminated. Some Nephilim bloodlines continued to do battle with the Israelites, though they were becoming less powerful and dying out. One tribe, the Anakim, allied themselves with the human tribes in Philistia. Goliath was thought to have been one of the last few descendants of the Nephilim.
Goliath’s height is given in the earliest manuscripts as 275 centimeters (9′). That’s hardly as awe-inspiring as the creature laying in Og’s bed, which measured, according to Deuteronomy, 400 centimeters (13′ 6″). That’s basically Yao Ming sitting on Shaquille O’Neal’s shoulders.
Biblically, descendants of the Nephilim could not have survived the Flood, even though Og and other giants are post-Flood figures. Some biblical literalists have attributed their later existence to the descendants of Noah’s family hooking up, once again, with demons. Or, being fallen angels and not human, they did survive the flood.
Jewish tradition gets deeper into information about the Nephilim and their descendants, going against the grain of the biblical account. It tells of Og booking passage on the Ark by promising to act as a slave to Noah and his family. Other accounts have him hanging on to the side of the Ark and riding the flood out rodeo-style.

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The Best Star Gazing Binoculars for 2015




Excerpt from space.com

Most people have two eyes. Humans evolved to use them together (not all animals do). People form a continuous, stereoscopic panorama movie of the world within in their minds. With your two eyes tilted upward on a clear night, there's nothing standing between you and the universe. The easiest way to enhance your enjoyment of the night sky is to paint your brain with two channels of stronger starlight with a pair of binoculars. Even if you live in — or near — a large, light-polluted city, you may be surprised at how much astronomical detail you'll see through the right binoculars!
Our editors have looked at the spectrum of current binocular offerings. Thanks to computer-aided design and manufacturing, there have never been more high-quality choices at reasonable prices. Sadly, there's also a bunch of junk out there masquerading as fine stargazing instrumentation. We've selected a few that we think will work for most skywatchers.
There was a lot to consider: magnification versus mass, field of view, prism type, optical quality ("sharpness"), light transmission, age of the user (to match "exit pupil" size, which changes as we grow older), shock resistance, waterproofing and more. 

The best binoculars for you

"Small" astronomy binoculars would probably be considered "medium" for bird watching, sports observation and other terrestrial purposes. This comes about as a consequence of optics (prism type and objective size, mostly). "Large" binoculars are difficult to use for terrestrial applications and have a narrow field of view. They begin to approach telescope quality in magnification, resolution and optical characteristics.

Most of our Editors' Choicesfor stargazing binoculars here are under $300. You can pay more than 10 times that for enormous binocular telescopes used by elite enthusiasts on special mounts! You'll also pay more for ruggedized ("mil spec," or military standard) binoculars, many of which suspend their prisms on shock mounts to keep the optics in precise alignment.

Also, our Editors' Choices use Porro prism optics. Compact binoculars usually employ "roof" prisms, which can be cast more cheaply, but whose quality can vary widely. [There's much more about Porro prisms in our Buyer's Guide.]
We think your needs are best served by reviewing in three categories.
  • Small, highly portable binoculars can be hand-held for viewing ease.
  • Medium binoculars offer higher powers of magnification, but still can be hand-held, if firmly braced.
  • Large binoculars have bigger "objective" lenses but must be mounted on a tripod or counterweighted arm for stability.
Here's a detailed look at our Editor's Choice selections for stargazing binoculars:

Best Small Binoculars 

Editor's Choice: Oberwerk Mariner 8x40 (Cost: $150)

Oberwerk in German means "above work." The brand does indeed perform high-level optical work, perfect for looking at objects above, as well as on the ground or water. Founder Kevin Busarow's Mariner series is not his top of the line, but it benefits greatly from engineering developed for his pricier models. The Oberwerk 8x40’s treat your eyes to an extremely wide field, at very high contrast, with razor-sharp focus; they are superb for observing the broad starscapes of the Milky Way. Just 5.5 inches (14 cm) from front to back and 6.5 inches wide (16.5 cm), the Mariners are compact and rugged enough to be your favorite "grab and go binoculars." But at 37 ounces, they may be more than a small person wants to carry for a long time.


Runner-Up: Celestron Cometron 7x50 (Cost: $30)

Yes, you read that price correctly! These Celestron lightweight, wide-field binoculars bring honest quality at a remarkably low price point. The compromise comes in the optics, particularly the prism's glass type (you might see a little more chromatic aberration around the edges of the moon, and the exit pupil isn't a nice, round circle). Optimized for "almost infinitely distant" celestial objects, these Cometrons won't focus closer than about 30 feet (9.1 meters).  But that's fine for most sports and other outdoor use. If you're gift-buying for multiple young astronomers – or you want an inexpensive second set for yourself – these binoculars could be your answer. Just maybe remind those young folks to be a little careful around water; Celestron claims only that the Cometrons are "water resistant," not waterproof. 


Honorable Mention: Swarovski Habicht 8x30 (Cost: $1,050)

From the legendary Austrian firm of Swarovski Optik, these "bins" are perfect. Really. Very sharp. Very lightweight. Very wide field. Very versatile. And very expensive! Our editors would have picked them if we could have afforded them. 

Honorable Mention: Nikon Aculon 7x50 (Cost: $110) 

Nikon's legendary optical quality and the large, 7mm exit pupil diameter make these appropriate as a gift for younger skywatchers. 

Best Medium Binoculars

Editor's Choice: Celestron SkyMaster 8x56 (Cost: $210)

A solid, chunky-feeling set of quality prisms and lenses makes these binoculars a pleasant, 38oz. handful. A medium wide 5.8 degrees filed of view and large 7mm exit pupil brings you gently into a sweet sky of bright, though perhaps not totally brilliant, stars. Fully dressed in a rubber wetsuit, these SkyMasters are waterproof. Feel free to take them boating or birding on a moist morning. Their optical tubes were blown out with dry nitrogen at the factory, then sealed. So you can expect them not to fog up, at least not from the inside. Celestron's strap-mounting points on the Skymaster 8x56 are recessed, so they don't bother your thumbs, but that location makes them hard to fasten. 


Runner-Up: Oberwerk Ultra 15x70 (Cost: $380)

The most rugged pair we evaluated, these 15x70s are optically outstanding. Seen through the Ultra's exquisitely multi-coated glass, you may find yourself falling in love with the sky all over again. Oberwerk's method of suspending their BAK4 glass Porro prisms offers greater shock-resistance than most competitors’ designs. While more costly than some comparable binoculars, they deliver superior value. Our only complaint is with their mass: At 5.5 lbs., these guys are heavy!  You can hand-hold them for a short while, if you’re lying down. But they are best placed on a tripod, or on a counterweighted arm, unless you like shaky squiggles where your point-source stars are supposed to be. Like most truly big binoculars, the eyepieces focus independently; there’s no center focus wheel. These "binos" are for true astronomers. 


Honorable Mention: Vixen Ascot 10x50 (Cost:$165)

These quirky binoculars present you with an extremely wide field. But they are not crash-worthy – don't drop them in the dark – nor are they waterproof, and the focus knob is not conveniently located. So care is needed if you opt for these Vixen optics. 

Best Large Binoculars

Don't even think about hand-holding this 156-ounce beast! The SkyMaster 25x100 is really a pair of side-by-side 100mm short-tube refractor telescopes. Factor the cost of a sturdy tripod into your purchase decision, if you want to go this big.  The monster Celestron comes with a sturdy support spar for mounting. Its properly multi-coated optics will haul in surprising detail from the sky.  Just make sure your skies are dark; with this much magnification, light pollution can render your images dingy. As with many in the giant and super-giant class of binoculars, the oculars (non-removable eyepieces) focus separately, each rotating through an unusually long 450 degrees.  Getting to critical focus can be challenging, but the view is worth it. You can resolve a bit of detail on face of the new moon (lit by "Earthshine") and pick out cloud bands on Jupiter; tha's pretty astonishing for binoculars. 


Runner-Up: Orion Astronomy 20x80 (Cost: $150)

These big Orions distinguish themselves by price point; they're an excellent value. You could pay 10 times more for the comparably sized Steiners Military Observer 20x80 binoculars! Yes, the Orions are more delicate, a bit less bright and not quite as sharp. But they do offer amazingly high contrast; you'll catch significant detail in galaxies, comets and other "fuzzies." Unusually among such big rigs, the Astronomy 20x80 uses a center focus ring and one "diopter" (rather than independently focusing oculars); if you’re graduating from smaller binoculars, which commonly use that approach, this may be a comfort. These binoculars are almost lightweight enough to hold them by hand. But don't do that, at least not for long periods. And don't drop them. They will go out of alignment if handled roughly. 


Honorable Mention: Barska Cosmos 25x100 (Cost: $230)

They are not pretty, but you're in the dark, right? Built around a tripod-mountable truss tube, these Barskas equilibrate to temperature quickly and give you decent viewing at rational cost. They make for a cheaper version of our Editors' Choice Celestron SkyMasters. 

Honorable Mention: Steiner Observer 20x80 (Cost: $1,500)

Not at all a practical cost choice for a beginning stargazer, but you can dream, can't you? These Steiner binoculars are essentially military optics "plowshared" for peaceful celestial observing. 

Why we chose NOT to review certain types

Image stabilized?

Binoculars with active internal image stabilization are a growing breed. Most use battery-powered gyroscope/accelerometer-driven dynamic optical elements. We have left this type out of our evaluation because they are highly specialized and pricey ($1,250 and up). But if you are considering active stabilization, you can apply the same judgment methods detailed in our Buyer's Guide.

Comes with a camera?

A few binoculars are sold with built-in cameras. That seems like a good idea. But it isn't, at least not for skywatching. Other than Earth's moon, objects in the night sky are stingy with their photons. It takes a lengthy, rock-steady time exposure to collect enough light for a respectable image. By all means, consider these binocular-camera combos for snapping Facebook shots of little Jenny on the soccer field. But stay away from them for astronomy.

Mega monster-sized?

Take your new binoculars out under the night sky on clear nights, and you will fall in love with the universe. You will crave more ancient light from those distant suns. That may translate into a strong desire for bigger stereo-light buckets.

Caution: The next level up is a quantum jump of at least one financial order of magnitude. But if you have the disposable income and frequent access to dark skies, you may want to go REALLY big. Binocular telescopes in this class can feature interchangeable matching eyepieces, individually focusing oculars, more than 30x magnification and sturdy special-purpose tripods. Amateurs using these elite-level stereoscopes have discovered several prominent comets.

Enjoy your universe

If you are new to lens-assisted stargazing, you'll find excellent enhanced views among the binocular choices above. To get in deeper and to understand how we picked the ones we did, jump to our Buyer's Guide: How to Choose Binoculars for Sky Watching.

You have just taken the first step to lighting up your brain with star fire. May the photons be with you. Always. 

Skywatching Events 2015

Once you have your new binoculars, it's time to take them for a spin. This year intrepid stargazers will have plenty of good opportunities to use new gear.

On March 20, for example, the sun will go through a total solar eclipse. You can check out the celestial sight using the right sun-blocking filters for binoculars, but NEVER look at the sun directly, even during a solar eclipse. It's important to find the proper filters in order to observe the rare cosmic show. 

Observers can also take a look at the craggy face of the moon during a lunar eclipse on April 4. Stargazers using binoculars should be able to pick out some details not usually seen by the naked eye when looking at Earth's natural satellite.

Skywatchers should also peek out from behind the binoculars for a chance to see a series of annual meteor showers throughout the year.

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Google Chairman Eric Schmidt: "The Internet Will Disappear"


 


Excerpt from hollywoodreporter.com

Google executive chairman Eric Schmidt on Thursday predicted the end of the Internet as we know it.

At the end of a panel at the World Economic Forum in Davos, Switzerland, where his comments were webcast, he was asked for his prediction on the future of the web. “I will answer very simply that the Internet will disappear,” Schmidt said.

“There will be so many IP addresses…so many devices, sensors, things that you are wearing, things that you are interacting with that you won’t even sense it,” he explained. “It will be part of your presence all the time. Imagine you walk into a room, and the room is dynamic. And with your permission and all of that, you are interacting with the things going on in the room.”

Concluded Schmidt: “A highly personalized, highly interactive and very, very interesting world emerges.”

The panel, entitled The Future of the Digital Economy, also featured Facebook COO Sheryl Sandberg and others.
Earlier in the debate, Schmidt discussed the issue of market dominance. The European Union has been looking at Google’s search market dominance in a long-running antitrust case, and the European parliament late last year even called for a breakup.
“You now see so many strong tech platforms coming, and you are seeing a reordering and a future reordering of dominance or leaders or whatever term you want to use because of the rise of the apps on the smartphone,” Schmidt said Thursday. “All bets are off at this point as to what the smartphone app infrastructure is going to look like” as a “whole new set” of players emerges to power smartphones, which are nothing but super-computers, the Google chairman argued. “I view that as a completely open market at this point.”

Asked about his recent trip to North Korea, Schmidt said the country has many Internet connections through data phones, but there is no roaming and web usage is “heavily supervised.” Schmidt said “it’s very much surveillance of use,” which he said was not good for the country and others.

Sandberg and Schmidt lauded the Internet as an important way to give more people in the world a voice. Currently, only 40 percent of people have Internet access, the Facebook COO said, adding that any growth in reach helps extend people’s voice and increase economic opportunity. “I’m a huge optimist,” she said about her outlook for the industry. “Imagine what we can do” once the world gets to 50 percent, 60 percent and more in terms of Internet penetration.
She cited women as being among the beneficiaries, saying the Internet narrows divides.

Schmidt similarly said that broadband can address governance issues, information needs, personal issues, women empowerment needs and education issues. “The Internet is the greatest empowerment of citizens … in many years,” he said. “Suddenly citizens have a voice, they can be heard.”
During another technology panel at the World Economic Forum on Thursday, Yahoo CEO Marissa Mayer, Liberty Global CEO Mike Fries and others answered questions on the need to regulate privacy standards on the Internet and for tech companies following the Snowden case, the Sony hack and the like.


Mayer said that the personalized Internet “is a better Internet,” emphasizing: “We don’t sell your personal data … We don’t transfer your personal data to third parties.” She said users own their data and need to have control, adding that people give up data to the government for tax assessment, social services and other purposes.
Fries said Liberty Global subscribers view billions of hours of content and generate billions of clicks, but added that “today we do nothing.” He explained: “We generate zero revenue from all of that information.” But he acknowledged that big data was big business for a lot of people.

Both executives said transparency was important to make sure users know privacy standards and the like.

Gunther Oettinger, a conservative German politician serving as the European Union’s commissioner for digital economy and society, said on the panel that “we need a convincing global understanding, we need a UN agency for data protection and security.” Asked what form that “understanding” should have, he said he was looking for “clear, pragmatic, market-based regulation.” Explained Oettinger: “It’s a public-private partnership.”

Fries said such a solution was likely not to happen in the near term, given the size of the EU. “I think it is going to take several years,” he said, adding that some countries’ parliaments would likely take a stab at it.

But he warned that a joint solution would make more sense. “We don’t want Germany to have its own Internet,” Fries said. “Some countries may build their own Internets” and “balkanize” the web, he warned.

Mayer said on the issue of regulation: “I like Tim’s idea better of the beneficent marketplace.” She spoke of fellow panelist and computer specialist Tim Berners-Lee, known as the inventor of the World Wide Web.

Asked how Yahoo stores and handles client records, she said the online giant “changed the way we store and communicate data” after Snowden and also changed encryptions between data centers. And the company protects users through encryption methods, she added. Mayer said that trust and confidence of Yahoo users has rebounded since.

Mayer was also asked what happens if a government asks for a user’s data, a question that has new significance after the recent terrorist attacks in Paris, which have led some to call for increased surveillance powers of the Internet for governments. Mayer said Yahoo always assesses if such a request is reasonable. “We have a very good track record for standing up to what’s not reasonable,” she said.

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Surprising discovery finds proteins can be assembled without genetic instructions ~ Sends scientists back to drawing board





Excerpt from news.bioscholar.com


A study has shown for the first time that the building blocks of proteins can be assembled without instructions from DNA or messenger RNA (mRNA).

A protein, Rqc2, was found playing a role similar to that of mRNA and specifying which amino acids, the building blocks of proteins, to be added in cell mechanism.

“In this case, we have a protein playing a role normally filled by mRNA,” said Adam Frost, assistant professor at University of California, San Francisco.

“This surprising discovery reflects how incomplete our understanding of biology is,” said first author Peter Shen, a postdoctoral fellow in biochemistry at the University of Utah in the US.

The researchers added that the findings have implications for new therapies to treat neurodegenerative diseases such as Alzheimer’s, Amyotrophic lateral sclerosis (ALS) or Huntington’s.

The researchers described that ribosomes are machines on a protein assembly line, linking together amino acids in an order specified by the genetic code.

RCQ protein
A new finding goes against dogma, showing for the first time that the building blocks of a protein, called amino acids, can be assembled by another protein, and without genetic instructions). The Rqc2 protein (yellow) binds tRNAs (dark blue, teal) which add amino acids (bright spot in middle) to a partially made protein (green). The complex binds the ribosome (white). Image Credit: Janet Iwasa, Ph.D., University of Utah

When something goes wrong, the ribosome is generally disassembled, the blueprint is discarded and the partly made protein is recycled.

The new study, however, revealed that before the incomplete protein is recycled, Rqc2 can prompt the ribosomes to add just two amino acids (of a total of 20) – alanine and threonine – over and over, and in any order.

The nonsensical sequence likely serves specific purposes. The code could signal that the partial protein must be destroyed, or it could be part of a test to see whether the ribosome is working properly, the researchers noted.

For the study, they fine-tuned a technique called cryo-electron microscopy to flash freeze, and then visualse, the quality control machinery in cells in action.

The findings appeared in the journal Science.

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Elusive dark matter may be detected with GPS satellites


This two-clocks-illustration shows the pattern of how two atomic clocks would desynchronize and then resynchronize due to a lump of dark matter sweeping through a Global Positioning System or other atomic clock based network. Photo courtesy of Andrei Derevianko, University of Nevada, Reno.


Excerpt from
sciencerecorder.com


Global Positioning System, or GPS for short, devices are typically used for navigation purposes. But this satellite network could also alert us to something else: the presence of dark matter.

Dark matter is thought to form 80% of the universe, but is difficult to detect because it rarely interacts with ordinary matter. Its makeup is unknown, as it has never been viewed by science. Some have suggested that dark matter is a particle; however, a new study indicates that dark matter may consist of kinks in the quantum field.

According to Andrei Derevianko at the University of Nevada, Reno, and Maxim Pospelov at the Perimeter Institute in Waterloo, Ontario, Canada, dark matter may be made of quantum field cracks that can be detected by GPS. The theory is a revolutionary one, and would change the nature of time and space where the kinds are located.

One of these elements is time, which is tracked by the extremely accurate GPS system. With a network of satellites spanning 50,000 kilometers and traveling through space at 300 kilometers a second, a cosmic kink could disturb the GPS clocks. This quantum crack would require 170 seconds to jump across the networks.

GPS clocks could be interrupted by other factors, but Deverianko and Pospelov believe that only dark matter could disturb the system’s timekeeping in a certain way.

Derevianko is currently pulling data from 15 years of GPS records to search for signs of dark matter’s presence. If no fingerprints are detected, he will use the ground-based atomic clocks belonging to the Network for European Accurate Time and Frequency Transfer.
If dark matter is nothing more than cosmic kinks, it could give some people a new thing to grumble about. “I hear these stories about people getting lost using GPS,” said Derevianko. “Now they could have another excuse: maybe it was dark matter that caused them to lose their way.”

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Galactic Federation of Light Saul May-19-2013

What is occurring planetwide is something so new and so startling. . .
05/19/2013 by John Smallman
http://johnsmallman.wordpress.com/2013/05/19/what-is-occurring-planetwide-is-something-so-new-and-so-startling/

All of humanity is poised, expectant, sensing an intense energy of change

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Galactic Federation of Light Archangel Michael April-26-2013

Spiritual Protection for the New Age by Archangel Michael Channelled through Natalie Glasson www.omn.org
Thanks to Méline Lafont: http://pleiadedolphininfos.blogspot.com/2013/04/spiritual-protection-for-new-age-by.html#more

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