Tag: level (page 3 of 28)

Spring Cleaning Tips for Body, Mind and Spirit

Excerpt from huffingtonpost.comAn extended winter throughout much of the U.S. and Canada really cut into the enjoyment of the spring season this year for many. One of our coaching students sent me photos of over a foot of snow this past May weekend...

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NASA Challenges People to Come Up With Designs for Mars Habitat –





Excerpt from perfscience.com

The space agency NASA has asked public to submit designs for a Mars habitat. NASA, along with the National Additive Manufacturing Innovation Institute, is holding a competition to design and build a 3-D printed habitat for deep space explorations like journey to Mars.  The multi-phase 3-D Printed Habitat Challenge has been specifically designed to advance the additive construction technology that is needed to develop sustainable housing solutions for earth and beyond.  As per experts, shelter is among most basic and crucial requirement for humans but carrying bulks of material to build up a habitat during a deep space mission would unnecessarily take the place in cargo that could be used for something important.  The first phase of the competition that was announced on Saturday will run through September 27. This phase calls on participants to develop state-of-the-art architectural concepts that take advantage of the unique capabilities 3-D printing offers.  The top 30 submissions will be considered and judged. Also winners will be awarded with prize money of $50,000 at the 2015 World Maker Faire in New York.  Sam Ortega, Centennial Challenges program manager, said, “This challenge definitely raises the bar from what we are currently capable of, and we are excited to see what the maker community does with it”... 
The space agency NASA has asked public to submit designs for a Mars habitat. NASA, along with the National Additive Manufacturing Innovation Institute, is holding a competition to design and build a 3-D printed habitat for deep space explorations like journey to Mars.
The multi-phase 3-D Printed Habitat Challenge has been specifically designed to advance the additive construction technology that is needed to develop sustainable housing solutions for earth and beyond.
As per experts, shelter is among most basic and crucial requirement for humans but carrying bulks of material to build up a habitat during a deep space mission would unnecessarily take the place in cargo that could be used for something important.
The first phase of the competition that was announced on Saturday will run through September 27. This phase calls on participants to develop state-of-the-art architectural concepts that take advantage of the unique capabilities 3-D printing offers.
The top 30 submissions will be considered and judged. Also winners will be awarded with prize money of $50,000 at the 2015 World Maker Faire in New York.
Sam Ortega, Centennial Challenges program manager, said, “This challenge definitely raises the bar from what we are currently capable of, and we are excited to see what the maker community does with it”.
Furthermore the second phase of the competition is divided into two levels i.e., the (Level 1) Structural Member Competition and the On-Site Habitat Competition (Level 2).
The Level 1 focuses on the fabrication technologies that are needed to manufacture structural components from a combination of indigenous materials and recyclables, or indigenous materials alone.
On the other hand, the Level 2 challenges competitors to construct full-scale habitats using indigenous materials or indigenous materials combined with recyclables.
- See more at: http://perfscience.com/content/2141815-nasa-challenges-people-come-designs-mars-habitat#sthash.vtPiW4bW.dpuf

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How to Turn Milk Into Healthy Probiotic Medicine

Anna Hunt, Staff WriterOur sterile, pre-packaged, convenient foods, coupled with a diet high in antibiotic-filled, factory-farmed meats, have resulted in an increased need for probiotic-rich foods and supplements if we are to maintain a healthy gut flora. An ideal balance of good and bad bacteria in the digestive system means improved digestion and better body function in general.Probiotic supplements, such as the high-quality brands BioImmersion and Kla [...]

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CRISPR-Cas9 modifies your DNA, under legal fire ~ Video




Excerpt from slashgear.com

A revolutionary method of editing the human genome has this week become the subject of a patent war. Back in April of 2014, patents were awarded by the USPTO (United States Patent and Trademark Office) to the Broad Institutes’ Dr. Feng Zhang, MIT, and Harvard to develop the technology behind "CRISPR-Cas9". 
This April, the UC Board of Regents’ legal team spoke with the USPTO about reconsidering their action, suggesting they award the patent to the inventor of the original method, UC Berkeley’s Jennifer Doudna. One way or another, this radical DNA modifier must be made. 

We need X-Men, after all.


The following video will explain what this genome-editing piece of technological breakthrough is all about. CRISPR-Cas9 is what it's called, and getting in to your body to make changes on a DNA level is what it's going for.

CRISPR-Cas9 works as a tiny scissors.

Utilizing the natural bacterial-level protective system used by your body to fight infections, CRISPR-Cas9 replicates the sequences of target DNA strands and latches on.

It's the connector that CRISPR-Cas9 makes real, and really programmable.

Your body provides the Cas9.* The Cas9 is the nuclease enzyme that cuts DNA strands.

*Correction - BACTERIA have Cas9, not our human selves. As helpful commenter "John" put so eloquently, "So far it has only been found in bacterial cells, and that's one of the things that makes it so amazing--a relatively simple molecular system that replicates many of the functions of our elaborate adaptive immune response, all in a single prokaryotic cell!"

Screen Shot 2015-05-15 at 10.11.42 AM
ABOVE: Image comes via Nature; Addgene, By Jonathan Corum, via NYT.

When a DNA sequence is cut, it may attempt to re-form. In doing so, it can create mutations.

But that's a discussion for another day.

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Genetically altered twin monkeys have been made using the CRISPR-Cas9 method. As you'll see in DOI: http://dx.doi.org/10.1016/j.cell.2014.01.027 in Cell Symposia "Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos", these monkeys are living large on gene-altered action.

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Today what's important is that two groups are fighting for the patents involved in CRISPR-Cas9.

A paper published online June 28 2012 by Science authored by Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A. Doudna, and Emmanuelle Charpentier describes the method: "A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity."

You can find this paper under code DOI: 10.1126/science.1225829.

Dr. Zhang suggests he demonstrated the CRISPR genome editing method before the 2012 paper was published by Dr. Doudna and Dr. Charpentier and crew. Dr. Doudna and Dr. Charpentier and crew suggest say Dr. Zhang's notebook (used as proof for patents) does not prove genome editing before the 2012 paper was published.

Can't we all just get along? Think of the monkeys!

Click to zoom

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12 Signs Your Dog Is Basically Your Furry Child





thedodo.com

1. Snack time is no longer a solo activity ...


2. ... And you always have a little reminder of when it's dinner time.


3. You always have a bed buddy — whether there's room for one or not.


4. The word "messy" is now taken to a whole new level in your household.


5. You have more pictures of your pup than you do of people.


6. Your house is full of toys that do not belong to you.


7. You never need to set an alarm — you'll definitely be woken up in the mornings.


8. You no longer have sole ownership of your possessions ...


9. ... Or your food.


10. You take more pride in their accomplishments than you do your own.


11. You'd do anything to keep them from getting scared.


12. And the most telling sign? Your pup is always the most surefire way to brighten your day.



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10 Ways to Salvage a Bad Morning Before Parting Ways

Excerpt from huffingtonpost.com1. Notice the good -- any and all good you can find -- even if it is simply, "I am so glad to see your face this morning," or, "You've always had a knack for unique clothing combinations!" 2. If someone is grumpy,...

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US Government Admits Americans Have Been Overdosed on Fluoride

Dr. MercolaThe US government has finally admitted they’ve overdosed Americans on fluoride and, for first time since 1962, are lowering its recommended level of fluoride in drinking water.1,2,3About 40 percent of American teens have dental fluorosis,4 a condition referring to changes in the appearance of tooth enamel—from chalky-looking lines and splotches to dark staining and pitting—caused by long-term ingestion of fluoride during the time teeth are forming.In some areas, fluoro [...]

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The Class-Domination Theory of Power

by G. William DomhoffNOTE: WhoRulesAmerica.net is largely based on my book,Who Rules America?, first published in 1967 and now in its7th edition. This on-line document is presented as a summary of some of the main ideas in that book.Who has predominant power in the United States? The short answer, from 1776 to the present, is: Those who have the money -- or more specifically, who own income-producing land and businesses -- have the power. George Washington was one of the biggest landowner [...]

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Nuclear Experimentation Year 70 – Playing With Madness

Ethan Indigo Smith, ContributorThe recent “news” on the nuclear situation in Iran brings to light the madhouse of cards on which the postmodern world is built. Or rather, it would bring the madness to light if the major media outlets of the world were not bought up and sold out to the military industrial complex, and therefore completely misinformed on the actions and dangers of the nuclear experimentation industry.The story is not just about [...]

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Quantum Entanglement Verified: Why Space Is Just The Construct That Gives The Illusion Of Separate Objects

“Space is just the construct that gives the illusion that there are separate objects” – Dr. Quantum (see video below)There is a phenomenon so strange, so fascinating, and so counter to what we believe to be the known scientific laws of the universe, that Einstein himself could not wrap his head around it. It’s called “quantum entanglement,” though Einstein referred to it as “spooky action at a distance.”An [...]

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6 Natural Solutions To Decontaminate Soil

Marco Torres, Prevent DiseaseWith a progressively educated population becoming more aware of the inherent dangers of the conventional food supply, urban farming has become hugely popular. However, more people are also becoming aware of contaminated soil and how heavy metals pose potential risks to their food crops. As backyard gardening continues to explode in popularity, we must ask how contaminated is our soil?Many municipalities in many countries are embracing urban agri [...]

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The Secret To A Meaningful Life In Just 7 ‘Magic’ Words

Excerpt from huffingtonpost.com Sometimes, it's the most fantastical, fictional characters that do the best job of teaching us about reality.New York Times bestselling author T.A. Barron spent decades creating the magical image of Merlin the wiza...

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Seattle Company Raises Minimum Wage to $70,000 a Year For All Employees!






Excerpt from nytimes.com

The idea began percolating, said Dan Price, the founder of Gravity Payments, after he read an article on happiness. It showed that, for people who earn less than about $70,000, extra money makes a big difference in their lives.

His idea bubbled into reality on Monday afternoon, when Mr. Price surprised his 120-person staff by announcing that he planned over the next three years to raise the salary of even the lowest-paid clerk, customer service representative and salesman to a minimum of $70,000.

“Is anyone else freaking out right now?” Mr. Price asked after the clapping and whooping died down into a few moments of stunned silence. “I’m kind of freaking out.”

If it’s a publicity stunt, it’s a costly one. Mr. Price, who started the Seattle-based credit-card payment processing firm in 2004 at the age of 19, said he would pay for the wage increases by cutting his own salary from nearly $1 million to $70,000 and using 75 to 80 percent of the company’s anticipated $2.2 million in profit this year.

Employees reacting to the news. The average salary at Gravity Payments had been $48,000 year. Credit Matthew Ryan Williams for The New York Times

The paychecks of about 70 employees will grow, with 30 ultimately doubling their salaries, according to Ryan Pirkle, a company spokesman. The average salary at Gravity is $48,000 year.

Mr. Price’s small, privately owned company is by no means a bellwether, but his unusual proposal does speak to an economic issue that has captured national attention: The disparity between the soaring pay of chief executives and that of their employees.

The United States has one of the world’s largest pay gaps, with chief executives earning nearly 300 times what the average worker makes, according to some economists’ estimates. That is much higher than the 20-to-1 ratio recommended by Gilded Age magnates like J. Pierpont Morgan and the 20th century management visionary Peter Drucker.

“The market rate for me as a C.E.O. compared to a regular person is ridiculous, it’s absurd,” said Mr. Price, who said his main extravagances were snowboarding and picking up the bar bill. He drives a 12-year-old Audi, which he received in a barter for service from the local dealer.

“As much as I’m a capitalist, there is nothing in the market that is making me do it,” he said, referring to paying wages that make it possible for his employees to go after the American dream, buy a house and pay for their children’s education.

Under a financial overhaul passed by Congress in 2010, the Securities and Exchange Commission was supposed to require all publicly held companies to disclose the ratio of C.E.O. pay to the median pay of all other employees, but it has so far failed to put it in effect. Corporate executives have vigorously opposed the idea, complaining it would be cumbersome and costly to implement.

Mr. Price started the company, which processed $6.5 billion in transactions for more than 12,000 businesses last year, in his dorm room at Seattle Pacific University with seed money from his older brother. The idea struck him a few years earlier when he was playing in a rock band at a local coffee shop. The owner started having trouble with the company that was processing credit card payments and felt ground down by the large fees charged.

When Mr. Price looked into it for her, he realized he could do it more cheaply and efficiently with better customer service.

The entrepreneurial spirit was omnipresent where he grew up in rural southwestern Idaho, where his family lived 30 miles from the closest grocery store and he was home-schooled until the age of 12. When one of Mr. Price’s four brothers started a make-your-own baseball card business, 9-year-old Dan went on a local radio station to make a pitch: “Hi. I’m Dan Price. I’d like to tell you about my brother’s business, Personality Plus.”

His father, Ron Price, is a consultant and motivational speaker who has written his own book on business leadership.

Dan Price came close to closing up shop himself in 2008 when the recession sent two of his biggest clients into bankruptcy, eliminating 20 percent of his revenue in the space of two weeks. He said the firm managed to struggle through without layoffs or raising prices. His staff, most of them young, stuck with him.

Aryn Higgins at work at Gravity Payments in Seattle. She and her co-workers are going to receive significant pay raises. Credit Matthew Ryan Williams for The New York Times

Mr. Price said he wasn’t seeking to score political points with his plan. From his friends, he heard stories of how tough it was to make ends meet even on salaries that were still well-above the federal minimum of $7.25 an hour.

“They were walking me through the math of making 40 grand a year,” he said, then describing a surprise rent increase or nagging credit card debt.

“I hear that every single week,” he added. “That just eats at me inside.”

Mr. Price said he wanted to do something to address the issue of inequality, although his proposal “made me really nervous” because he wanted to do it without raising prices for his customers or cutting back on service.

Of all the social issues that he felt he was in a position to do something about as a business leader, “that one seemed like a more worthy issue to go after.”

He said he planned to keep his own salary low until the company earned back the profit it had before the new wage scale went into effect.

Hayley Vogt, a 24-year-old communications coordinator at Gravity who earns $45,000, said, “I’m completely blown away right now.” She said she has worried about covering rent increases and a recent emergency room bill.

“Everyone is talking about this $15 minimum wage in Seattle and it’s nice to work someplace where someone is actually doing something about it and not just talking about it,” she said.

The happiness research behind Mr. Price’s announcement on Monday came from Angus Deaton and Daniel Kahneman, a Nobel Prize-winning psychologist. They found that what they called emotional well-being — defined as “the emotional quality of an individual’s everyday experience, the frequency and intensity of experiences of joy, stress, sadness, anger, and affection that make one’s life pleasant or unpleasant” — rises with income, but only to a point. And that point turns out to be about $75,000 a year.

Of course, money above that level brings pleasures — there’s no denying the delights of a Caribbean cruise or a pair of diamond earrings — but no further gains on the emotional well-being scale.
As Mr. Kahneman has explained it, income above the threshold doesn’t buy happiness, but a lack of money can deprive you of it.
Phillip Akhavan, 29, earns $43,000 working on the company’s merchant relations team. “My jaw just dropped,” he said. “This is going to make a difference to everyone around me.”

At that moment, no Princeton researchers were needed to figure out he was feeling very happy.

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