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Lab for genetic modification of human embryos just $2,000 away – report


Reuters / Christian Charisius



Reuters

With the right expertise in molecular biology, one could start a basic laboratory to modify human embryos using a genome-editing computer technique all for a couple thousand dollars, according to a new report.

Genetic modification has received heightened scrutiny recently following last week’s announcement that Chinese researchers had, for the first time, successfully edited human embryos’ genomes. 
The team at Sun Yat-Sen University in Guangzhou, China, used CRISPR (clustered regularly interspaced palindromic repeats), a technique that relies on “cellular machinery” used by bacteria in defense against viruses. 

This machinery is copied and altered to create specific gene-editing complexes, which include the wonder enzyme Cas9. The enzyme works its way into the DNA and can be used to alter the molecule from the inside. The combination is attached to an RNA guide that takes the gene-editing complex to its target, telling Cas9 where to operate. 

Use of the CRISPR technique is not necessarily relegated to the likes of cash-flush university research operations, according to a report by Business Insider. 


Geneticist George Church, who runs a top CRISPR research program at the Harvard Medical School, said the technique could be employed with expert knowledge and about half of the money needed to pay for an average annual federal healthcare plan in 2014 -- not to mention access to human embryos. 

"You could conceivably set up a CRISPR lab for $2,000,” he said, according to Business Insider. 

Other top researchers have echoed this sentiment. 

"Any scientist with molecular biology skills and knowledge of how to work with [embryos] is going to be able to do this,” Jennifer Doudna, a biologist at the University of California, Berkeley, recently told MIT Tech Review, which reported that Doudna co-discovered how to edit genetic code using CRISPR in 2012. 

Last week, the Sun Yat-Sen University research team said it attempted to cure a gene defect that causes beta-thalassemia (a genetic blood disorder that could lead to severe anemia, poor growth, skeletal abnormalities and even death) by editing the germ line. For that purpose they used a gene-editing technique based on injecting non-viable embryos with a complex, which consists of a protective DNA element obtained from bacteria and a specific protein. 

"I suspect this week will go down as a pivotal moment in the history of medicine," wrote science journalist Carl Zimmer for National Geographic.


Response to the new research has been mixed. Some experts say the gene editing could help defeat genetic diseases even before birth. Others expressed concern. 

“At present, the potential safety and efficacy issues arising from the use of this technology must be thoroughly investigated and understood before any attempts at human engineering are sanctioned, if ever, for clinical testing,” a group of scientists, including some who had worked to develop CRISPR, warned in Science magazine. 

Meanwhile, the director of the US National Institutes for Health (NIH) said the agency would not fund such editing of human embryo genes. 

“Research using genomic editing technologies can and are being funded by NIH,” Francis Collins said Wednesday. “However, NIH will not fund any use of gene-editing technologies in human embryos. The concept of altering the human germline in embryos for clinical purposes ... has been viewed almost universally as a line that should not be crossed.”

Although the discovery of CRISPR sequences dates back to 1987 – when it was first used to cure bacteria of viruses – its successes in higher animals and humans were only achieved in 2012-13, when scientists achieved a revolution by combining the resulting treatment system with Cas9 for the first time. 


On April 17, the MIT’s Broad Institute announced that has been awarded the first-ever patent for working with the Crisp-Cas9 system. 

The institute’s director, Eric Lander, sees the combination as “an extraordinary, powerful tool. The ability to edit a genome makes it possible to discover the biological mechanisms underlying human biology.”

The system’s advantage over other methods is in that it can also target several genes at the same time, working its way through tens of thousands of so-called 'guide' RNA sequences that lead them to the weapon to its DNA targets. 

Meanwhile, last month in the UK, a healthy baby was born from an embryo screened for genetic diseases, using karyomapping, a breakthrough testing method that allows doctors to identify about 60 debilitating hereditary disorders.

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IBM advances bring quantum computing closer to reality



ibm research jerry chow
 
Research scientist Jerry Chow performs a quantum computing experiment at IBM's Thomas J. Watson Research Center in Yorktown Heights, N.Y. Jon Simon/IBM


Excerpt from computerworld.com
By Sharon Gaudin

IBM scientists say they have made two critical advances in an industrywide effort to build a practical quantum computer, shaving years off the time expected to have a working system.

"This is critical," said Jay Gambetta, IBM's manager of theory of quantum computing. "The field has got a lot more competitive. You could say the [quantum computing] race is just starting to begin… This is a small step on the journey but it's an important one."

Gambetta told Computerworld that IBM's scientists have created a square quantum bit circuit design, which could be scaled to much larger dimensions. This new two-dimensional design also helped the researchers figure out a way to detect and measure errors.
Quantum computing is a fragile process and can be easily thrown off by vibrations, light and temperature variations. Computer scientists doubt they'll ever get the error rate down to that in a classical computer.


Because of the complexity and sensitivity of quantum computing, scientists need to be able to detect errors, figure out where and why they're happening and prevent them from recurring.

IBM says its advancement takes the first step in that process.
"It tells us what errors are happening," Gambetta said. "As you make the square [circuit design] bigger, you'll get more information so you can see where the error was and you can correct for it. We're showing now that we have the ability to detect, and we're working toward the next step, which would allow you to see where and why the problem is happening so you can stop it from happening."

Quantum computing is widely thought to be the next great step in the field of computing, potentially surpassing classical supercomputers in large-scale, complex calculations. 

Quantum computing would be used to cull big data, searching for patterns. It's hoped that these computers will take on questions that would lead to finding cures for cancer or discovering distant planets – jobs that might take today's supercomputers hundreds of years to calculate.

IBM's announcement is significant in the worlds of both computing and physics, where quantum theory first found a foothold.

Quantum computing, still a rather mysterious technology, combines both computing and quantum mechanics, which is one of the most complex, and baffling, areas of physics. This branch of physics evolved out of an effort to explain things that traditional physics is unable to.

With quantum mechanics, something can be in two states at the same time. It can be simultaneously positive and negative, which isn't possible in the world as we commonly know it. 

For instance, each bit, also known as a qubit, in a quantum machine can be a one and a zero at the same time. When a qubit is built, it can't be predicted whether it will be a one or a zero. A qubit has the possibility of being positive in one calculation and negative in another. Each qubit changes based on its interaction with other qubits.

Because of all of these possibilities, quantum computers don't work like classical computers, which are linear in their calculations. A classical computer performs one step and then another. A quantum machine can calculate all of the possibilities at one time, dramatically speeding up the calculation.

However, that speed will be irrelevant if users can't be sure that the calculations are accurate.

That's where IBM's advances come into play.

"This is absolutely key," said Jim Tully, an analyst with Gartner. "You do the computation but then you need to read the results and know they're accurate. If you can't do that, it's kind of meaningless. Without being able to detect errors, they have no way of knowing if the calculations have any validity."

If scientists can first detect and then correct these errors, it's a major step in the right direction to building a working quantum computing system capable of doing enormous calculations. 

"Quantum computing is a hard concept for most to understand, but it holds great promise," said Dan Olds, an analyst with The Gabriel Consulting Group. "If we can tame it, it can compute certain problems orders of magnitude more quickly than existing computers. The more organizations that are working on unlocking the potential of quantum computing, the better. It means that we'll see something real that much sooner."
However, there's still debate over whether a quantum computer already exists.

A year ago, D-Wave Systems Inc. announced that it had built a quantum system, and that NASA, Google and Lockheed Martin had been testing them.

Many in the computer and physics communities doubt that D-Wave has built a real quantum computer. Vern Brownell, CEO of the company, avows that they have.

"I think that quantum computing shows promise, but it's going to be quite a while before we see systems for sale," said Olds.
IBM's Gambetta declined to speculate on whether D-Wave has built a quantum computing but said the industry is still years away from building a viable quantum system.

"Quantum computing could be potentially transformative, enabling us to solve problems that are impossible or impractical to solve today," said Arvind Krishna, senior vice president and director of IBM Research, in a statement.

IBM's research was published in Wednesday's issue of the journal Nature Communications.

quantum computing infographics ibm

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Cosmic tsunamis can regenerate ‘dead’ galaxies






Excerpt from thespacereporter.com



Astronomers have recently discovered that giant cosmic shockwaves emanating from colliding galaxy clusters are capable of jumpstarting new star generation.

According to a Nature World News report, galaxies are often clustered into groups containing “red and dead” galaxies that stopped forming new stars long ago. Scientists now believe that these “dead” galaxies can be brought back to “life” by colossal cosmic tsunamis.

To uncover this phenomenon, an international team of researchers observed how galaxy clusters can absorb smaller clusters much as a growing city absorbs its suburbs. When galaxy clusters collide during this absorption process, a huge shockwave of energy is created. This shockwave can re-energize the star formation process, causing dormant galaxies to begin producing new stars again.

Scientists from the University of Lisbon and Leiden Observatory came to this conclusion after studying the merging galaxy cluster officially known as CIZA J2242.8+5301 and affectionately known as the “Sausage.” The Sausage cluster, located 2.3 billion light-years away, showed evidence of its dormant galaxies coming to life with a new round of star formation.

“We assumed that the galaxies would be on the sidelines for this act, but it turns out they have a leading role. The comatose galaxies in the Sausage cluster are coming back to life, with stars forming at a tremendous rate. When we first saw this in the data, we simply couldn’t believe what it was telling us,” Andra Stroe of Liden Observatory said in a statement.The researchers are observing an event that actually unfolded one billion years ago, when the 6-million-mph shockwave spread out from the collision of the clusters. The team believes that the new star formation was instigated by the shockwave’s affect on galactic gas.

“Much like a teaspoon stirring a mug of coffee, the shocks lead to turbulence in the galactic gas. These then trigger an avalanche-like collapse, which eventually leads to the formation of very dense, cold gas clouds, which are vital for the formation of new stars,” Stroe said.

Despite the vigorous production of new stars in this instance, the team believes that, after the initial effects of the tsunami take place, the galaxies fall to an even deeper state of dormancy than before.

David Sobral of the University of Lisbon explains that “star formation at this rate leads to a lot of massive, short-lived stars coming into being, which explode as supernovae a few million years later. The explosions drive huge amounts of gas out of the galaxies and with most of the rest consumed in star formation, the galaxies soon run out of fuel. If you wait long enough, the cluster mergers make the galaxies even more red and dead – they slip back into a coma and have little prospect of a second resurrection.”

The study was published in the journal Monthly Notices of the Royal Astronomical Society.

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17 Surprising Reasons You’re Stressed Out





Excerpt from huffingtonpost.com
By Amanda MacMillan


You're probably all too aware of the major sources of stress in your life -- money, your terrible commute, the construction workers who start jackhammering at 5 a.m. But stress and anxiety don't have to just come from obvious or even negative sources. "There are plenty of chronic strains and low-grade challenges that don't necessarily overwhelm you in the moment, but almost take more of a toll in the long run," says Scott Schieman, Ph.D., professor of sociology at the University of Toronto. These are some of unexpected reasons why you might feel anxious or agitated. By recognizing them for what they are, says Schieman, you can better prepare to cope.

1. Your Significant Other
Even if you have a blissfully happy relationship with your live-in partner or spouse, you're both bound to do things that get on each other's nerves. "Early in the relationship, it's usually about space and habits -- like whether you squeeze the toothpaste from the middle or the bottom of the tube," says Ken Yeager, Ph.D., associate professor of psychiatry at the Ohio State University Wexner Medical Center. "Later on, you might clash over parenting style or financial issues, and finding a unified front to face these issues together." So what's the key to surviving and thriving in your life together? Finding balance, says Yeager: spending the right amount of time together (not too much and not too little), making compromises, keeping communication open and honest, and remembering to acknowledge what you love about each other on a daily basis.


2. Everyday Annoyances
We're told not to sweat the small stuff, but sometimes it's the little things that have the biggest impact on our mood: the never-ending phone calls with your insurance company, the rude cashier at the grocery store, the 20 minutes you lose looking for a parking space. "We let these things bother us because they trigger unconscious fears," says Yeager -- fears of being seen as irresponsible, of being bullied or embarrassed, or of being late all the time, for example. "Sometimes you need to take a step back and realize that you're doing the best you can given the circumstances." 


3. Other People's Stress
Stress is contagious, according to a 2014 German study: In a series of experiments, most participants who simply observed others completing a stressful task experienced an increase themselves in production of the stress hormone cortisol -- a phenomenon known as empathic stress. You can also experience stress when someone you know is affected by a traumatic event, like a car crash or a chronic illness. "You start to worry, 'Oh my gosh, could that happen to me?'," says Yeager. "We tend not to think about these things until they hit close to home."


4. Social Media social media
It may seem like Facebook is the only way you keep up with the friends you don't see regularly -- which, during particularly busy times, can be just about all of them. The social network also has a downside, according to a 2015 study from the Pew Research Center: It can make you aware of stressful situations in your friends' lives, which in turn can add more stress to your life. The Pew report didn't find that social media users, overall, had higher levels of stress, but previous studies have suggested that frequent social-media use can be associated with negative body image and prolonged breakup pain.


5. Distraction
A distraction can be a good thing then when it takes your mind off of a stressful situation or difficult decision, like when you take a break from work to meet a friend for lunch. But it works the other way, as well: When you're so busy thinking about something else that you can't enjoy what's going on around you, that kind of distraction can be a recipe for stress. Practicing mindfulness gives you brain the refresh it needs, says Richard Lenox, director of the Student Counseling Center at Texas Tech University. Paying full attention to your surroundings when you're walking and driving can help, he adds. "Stress and anxiety tend to melt away when our mind is focused on the present." 


6. Your Childhood
Traumatic events that happened when you were a kid can continue to affect your stress levels and overall health into adulthood. A 2014 University of Wisconsin-Madison study found that these childhood experiences may actually change parts of the brain responsible for processing stress and emotion. The way you were raised can also have a lasting impact on your everyday angst, suggests a 2014 Johns Hopkins University study. Researchers found that children of parents with social anxiety disorders are more likely to develop "trickle-down anxiety" -- not simply because of their genes, but because of their parents' behaviors toward them such as a lack of warmth and emotion, or high levels of criticism and doubt.


7. Tea And Chocolate
You probably know to take it easy on the coffee when you're already feeling on edge. "Caffeine is always going to make stress worse," says Yeager. But you may not think as much about drinking several cups of tea at once, or chowing down on a bar of dark chocolate -- both of which can contain nearly as much caffeine as a cup of joe. "Chocolate is a huge caffeine source," says Yeager. "I know people who don't drink coffee but they'll eat six little candy bars in a two-hour period because they want the same kind of jolt." Too much caffeine, in any form, can cause problems with sleep, digestion, and irritability. 


8. Your Expectations woman trail running
When things don't go the way you've planned, do you tend to get upset and act defensively, or do you roll with the punches and set off on a new plan? If it's the former, you could be contributing to a mindset of pessimism and victimization that will slowly wear you down, even when things may not be as bad as they seem. "Your level of serenity is inversely proportionate to your expectations," says Yeager. That doesn't mean you shouldn't set ambitious goals for yourself or settle for less than what you want, of course, but being realistic about what's truly possible is important, as well.


9. Your Reaction To Stress
If you tend to deal with stressful situations by working long hours, skipping your workouts, and bingeing on junk food, we've got some bad news: You're only making it worse. "We know that physical activity and healthy foods will help your body better deal with stress, and yet we often avoid them when we need them the most," says Yeager. "People really need to think about this downward spiral we get into and work harder to counteract it."


10. Multitasking
Think you're being super efficient by tackling four tasks at once? Chances are you're not -- and it's only decreasing your productivity while increasing your stress. A 2012 University of Irvine study, for example, found that people who responded to emails all day long while also trying to get their work done experienced more heart-rate variability (an indicator of mental stress) than those who waited to respond to all of their emails at one time. Focusing on one task at a time can ensure that you're doing that job to the best of your abilities and getting the most out of it, so you won't have to worry about or go back and fix it later, says Schieman. And don't worry: You'll have enough time to do it all. In fact, you may discover you have more time than you thought.


11. Your Favorite Sport
Watching a tight game of college hoops can stress you out -- even if your alma mater wins. "The body doesn't distinguish between 'bad' stress from life or work and 'good' stress caused by game-day excitement," says Jody Gilchrist, a nurse practitioner at the University of Alabama at Birmingham’s Heart and Vascular Clinic. Watching sports can even trigger the body's sympathetic nervous system, releasing adrenaline and reducing blood flow to the heart. Those temporary consequences aren't usually anything to be concerned about, but over time, chronic stress can lead to high blood pressure and increased disease risk. And, of course, it doesn't help if you're adding alcohol and binge-eating to a situation that's already stressful on your body. You may not be able to control the outcome of the game, says Gilchrist, but you can limit its effects on your own body. 


12. Digital Devices laptop in bed
Whether you're using it for work or play, technology may play a large role in your mental health, says Yeager. Using computers or e-readers too close to bedtime could lead to sleep problems, he says, and spending too much time virtually socializing can make real-life interactions seem extra stressful. (Plus, texting doesn't trigger the same feel-good hormones as face-to-face talk does.) Then there's the dreaded "work creep," says Schieman, when smartphones allow employees to be tethered to their jobs, even during off-hours. "People say they're only going to check email for an hour while they're on vacation, but the problem with email is that they're filled with responsibilities, new tasks, and dilemmas that are going to be hard to compartmentalize and put out of your head once that hour is up."


13. Your (Good) Health
While it may not be as stressful as having a chronic illness or getting bad news at the doctor's office, even people in the best shape of their lives worry about their bodies, their diets, and their fitness levels. In fact, people who take healthy living to an extreme may experience some rather unhealthy side effects. People who follow low-carb diets, for example, are more likely to report being sad or stressed out, while those on any kind of restrictive meal plan may feel more tired than usual. And it's not unheard of for someone to become obsessed with healthy eating (known as orthorexia) or working out (gymorexia). Like any form of perfectionism, these problems can be stressful at best, and extremely dangerous at worst.


14. Housework
Does folding laundry help you feel calm, or does it make your blood boil? If you're in a living situation where you feel you're responsible for an unfair share of work, even chores you once enjoyed may start to feel like torture. "Dividing up housework and parenting responsibilities can be tricky, especially if both partners work outside the home," says Schieman. "And whether you define that division of labor as equal or unequal can really change your attitude toward it."


15. Uncertainty
Stress can be defined as any perceived or actual threat, says Yeager, so any type of doubt that's looming over you can contribute to your anxiety levels on a daily basis. "When you know something could change at any minute, you always have your guard up and it's hard to just relax and enjoy anything." Financial uncertainty may be the most obvious stressor -- not being sure if you'll keep your job during a round of layoffs, or not knowing how you'll pay your credit card bill. Insecurities in other areas of life, like your relationship or your housing status, can eat away at you too.


16. Your Pet bulldog puppy
No matter how much you love your furry friends, there's no question that they add extra responsibility to your already full plate. Even healthy animals need to be fed, exercised, cleaned up after, and given plenty of attention on a regular basis -- and unhealthy ones can be a whole other story. "Pets can be the most positive source of unconditional love, but at the same time they require an extreme amount of energy," says Yeager. People also tend to underestimate the stress they'll experience when they lose a pet. "I've had people in my office tell me they cried more when their dog died than when their parent died. It's a very emotional connection."


17. Your Education
Having a college degree boosts your odds of landing a well-paying job, so although you're less likely to suffer from money-related anxiety, your education can bring on other types of stress, according to a 2014 study by Schieman and his University of Toronto colleagues. His research found that highly educated people were more likely to be stressed out thanks to job pressures, being overworked, and conflicts between work and family. "Higher levels of authority come with a lot more interpersonal baggage, such as supervising people or deciding whether they get promotions," says Schieman. "With that type of responsibility, you start to take things like incompetency and people not doing their jobs more personally, and it bothers you more."

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New Light on Our Accelerating Universe –"Not as Fast as We Thought"

 A Type Ia supernova, SN1994D, is shown exploding in lower left corner of the image at the top of the page of the galaxy NGC 4526 taken by the Hubble Space Telescope. (High-Z Supernova Search Team, HST, NASA)Excerpt from dailygalaxy.com Cer...

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New research shows Universe expansion pace isn’t as fast as assumed earlier



universe


Excerpt from thewestsidestory.net

The Universe is expanding and any student of astronomy will vouch to this fact. However according to a team of astronomers the acceleration of the universe may not be as quick as it was assumed earlier.

A team of astronomers have discovered that certain types of supernova are more varied than earlier thought of and in the process have led to the biggest mystery of the universe-how fast is the universe expanding after the big bang?

Peter A. Milne of the University of Arizona said, “We found that the differences are not random, but lead to separating Ia supernovae into two groups, where the group that is in the minority near us are in the majority at large distances — and thus when the universe was younger, there are different populations out there, and they have not been recognized. The big assumption has been that as you go from near to far, type Ia supernovae are the same. That doesn’t appear to be the case.”
The discovery throws new light on the currently accepted view of the universe expanding at a faster and faster rate pulled apart by an unknown force called dark energy this observation resulted in 2011 Nobel Prize for Physics.
Milne said, “The idea behind this reasoning, is that type Ia supernovae happen to be the same brightness — they all end up pretty similar when they explode. Once people knew why, they started using them as mileposts for the far side of the universe.The faraway supernovae should be like the ones nearby because they look like them, but because they’re fainter than expected, it led people to conclude they’re farther away than expected, and this in turn has led to the conclusion that the universe is expanding faster than it did in the past.”
The researchers felt that the accelerating universe can be explained on the basis of color difference in between two groups of supernova leaving less acceleration than earlier assumed and in the process will require lesser dark energy.

Milne said, “We’re proposing that our data suggest there might be less dark energy than textbook knowledge, but we can’t put a number on it, until our paper, the two populations of supernovae were treated as the same population. To get that final answer, you need to do all that work again, separately for the red and for the blue population.

Type la supernovae are considered as a benchmark for far away sources of light they do have a fraction of variability which has limited our knowledge of the size of the universe.
The distance of objects with the aid of our binocular vision and the best space-based telescopes and most sophisticated techniques works out in the range of ten or twenty thousand light years. 
However as compared to the vastness of space, this is just pea nuts.
For Distances greater than that it is imperative to compare the absolute and observed brightness of well understood objects and to use the difference to determine the object’s distance.

In astronomy it is difficult to find an object of known brightness since there are examples of both bright and dim stars and galaxies. However there is one event which can be used to work out its absolute brightness. Supernovas are the final stages of a dying star and it explodes with such violence, the flash can be seen across the vast universe.

Type la Supernovae occurs in a binary star system when a white dwarf scoops off mass from its fellow star. This reproducible mechanism gives a well determined brightness and therefore scientists term such Type la supernovae as ‘standard candles’.

Astronomers found that the Type la supernovae is so uniform that it has been designated as cosmic beacons and used to assess the depths of the universe. It is now revealed that they fall into different populations and are not very uniform as previously thought. .

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Our sun is five billion years younger than most other stars in our galaxy






Excerpt from stgist.com



The sun, or the nearest star from Earth, was formed around 5 billion years after the Milky Way galaxy’s peak production of stars, a new research published in the Astrophysical Journal. 

Using multiple ground based, and space telescopes, including the Magellan Telescopes located at Las Campanas Observatory in South America, a new study was able to confirm that the closest star from us, the Sun, was formed after the so-called stellar “baby boom” of the Milky Way galaxy.

It’s like traveling back in time. Researchers from Texas A&M University in College Station, headed by astronomer Casey Papovich, were able to see the undepicted past of our own galaxy by observing similar regions located billions of light years away from us.

The “baby boom” happened around 10 billion years ago, the new study published in Astrophysical Journal revealed. At that time, the Milky Way galaxy was producing 30 times more stars than today. If so, then our solar system’s 4.6 billion years old Sun was formed more than 5 billion years after the production peak.

Sun’s late formation allowed the solar system we know today to produce planets with heavier elements. Scientists say elements heavier than hydrogen and helium became more abundant in “late to the game systems”, and the death of massive stars that were formed before the Sun had provided materials needed to form planets, including Earth and its complex life forms.

Scientists scanned through a collection of more than 24,000 galaxies, and took at least 2,000 snapshots of galaxies that closely resemble our own. The census has provided the most complete picture yet of how spiral galaxies similar to Milky Way form in the universe.

According to Mr. Papovich, the lead author of the study who also serves as an associate professor in the Department of Physics and Astronomy at A&M University in Texas, they know where to find traces by analyzing how galaxies like our own were formed.

Papovich said his team has provided a data that clearly show the rapid phase of growth around 9 to 10 billion years ago, or at least more than 5 billion years after our Sun formed. They also found the connection between the size of the galaxy, and the formation of stars.

Surprisingly, the robust collection of distant galaxies confirmed that stars formed inside the Milky Way, instead of forming in other smaller baby galaxies that later merged to join the system.

In separate studies, scientists were able to confirm that our own solar system is wetter than thought. Beyond Earth, celestial objects like Jupiter’s Galilean moons Europa and Ganymede, Saturn’s Enceladus, and even the dwarf planet Ceres in the asteroid belt, are hosting fluid slightly similar to Earth’s — and it is highly possible that the Sun’s late formation allowed this setup to exist.

Papovich who worked alongside Texas A&M postdoctoral researchers Vithal Tilvi and Ryan Quadri, were joined by at least two dozen astronomers from other countries. The research is published April 9th entitled “ZFOURGE/CANDELS: ON THE EVOLUTION OF M* GALAXY PROGENITORS FROM z = 3 TO 0.5*.” The research was funded by NASA

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Did natural selection make the Dutch the tallest people on the planet?

Dutch national women's field hockey team



Excerpt from news.sciencemag.org
ByMartin Enserink

AMSTERDAM—Insecure about your height? You may want to avoid this tiny country by the North Sea, whose population has gained an impressive 20 centimeters in the past 150 years and is now officially the tallest on the planet. Scientists chalk up most of that increase to rising wealth, a rich diet, and good health care, but a new study suggests something else is going on as well: The Dutch growth spurt may be an example of human evolution in action.
The study, published online today in the Proceedings of the Royal Society B, shows that tall Dutch men on average have more children than their shorter counterparts, and that more of their children survive. That suggests genes that help make people tall are becoming more frequent among the Dutch, says behavioral biologist and lead author Gert Stulp of the London School of Hygiene & Tropical Medicine.

"This study drives home the message that the human population is still subject to natural selection," says Stephen Stearns, an evolutionary biologist at Yale University who wasn't involved in the study. "It strikes at the core of our understanding of human nature, and how malleable it is." It also confirms what Stearns knows from personal experience about the population in the northern Netherlands, where the study took place: "Boy, they are tall."

For many years, the U.S. population was the tallest in the world. In the 18th century, American men were 5 to 8 centimeters taller than those in the Netherlands. Today, Americans are the fattest, but they lost the race for height to northern Europeans—including Danes, Norwegians, Swedes, and Estonians—sometime in the 20th century.

Just how these peoples became so tall isn't clear, however. Genetics has an important effect on body height: Scientists have found at least 180 genes that influence how tall you become. Each one has only a small effect, but together, they may explain up to 80% of the variation in height within a population. Yet environmental factors play a huge role as well. The children of Japanese immigrants to Hawaii, for instance, grew much taller than their parents. Scientists assume that a diet rich in milk and meat played a major role.

The Dutch have become so much taller in such a short period that scientists chalk most of it up to their changing environment. As the Netherlands developed, it became one of the world's largest producers and consumers of cheese and milk. An increasingly egalitarian distribution of wealth and universal access to health care may also have helped.

Still, scientists wonder whether natural selection has played a role as well. For men, being tall is associated with better health, attractiveness to the opposite sex, a better education, and higher income—all of which could lead to more reproductive success, Stulp says.
Yet studies in the United States don't show this. Stulp's own research among Wisconsinites born between 1937 and 1940, for instance, showed that average-sized men had more children than shorter and taller men, and shorter women had more children than those of average height. Taken together, Stulp says, this suggests natural selection in the United States pulls in the opposite direction of environmental factors like diet, making people shorter instead of taller. That may explain why the growth in average American height has leveled off.

Stulp—who says his towering 2-meter frame did not influence his research interest—wondered if the same was true in his native country. To find out, he and his colleagues turned to a database tracking key life data for almost 100,000 people in the country's three northern provinces. The researchers included only people over 45 who were born in the Netherlands to Dutch-born parents. This way, they had a relatively accurate number of total children per subject (most people stop having children after 45) and they also avoided the effects of immigration.

In the remaining sample of 42,616 people, taller men had more children on average, despite the fact that they had their first child at a higher age. The effect was small—an extra 0.24 children at most for taller men—but highly significant. (Taller men also had a smaller chance of remaining childless, and a higher chance of having a partner.)  The same effect wasn't seen in women, who had the highest reproductive success when they were of average height.  The study suggests this may be because taller women had a smaller chance of finding a mate, while shorter women were at higher risk of losing a child.

Because tall men are likely to pass on the genes that made them tall, the outcome suggests that—in contrast to Americans—the Dutch population is evolving to become taller, Stulp says. "This is not what we've seen in other studies—that's what makes it exciting," says evolutionary biologist Simon Verhulst of the University of Groningen in the Netherlands, who was Stulp's Ph.D. adviser but wasn't involved in the current study. Verhulst points out that the team can't be certain that genes involved in height are actually becoming more frequent, however, as the authors acknowledge.

The study suggests that sexual selection is at work in the Dutch population, Stearns says: Dutch women may prefer taller men because they expect them to have more resources to invest in their children. But there are also other possibilities. It could be that taller men are more resistant to disease, Stearns says, or that they are more likely to divorce and start a second family. "It will be a difficult question to answer.”

Another question is why tall men in Holland are at a reproductive advantage but those in the United States are not. Stulp says he can only speculate. One reason may be that humans often choose a partner who's not much shorter or taller than they are themselves. Because shorter women in the United States have more children, tall men may do worse than those of average height because they're less likely to partner with a short woman.

In the end, Stearns says, the advantage of tall Dutchmen may be only temporary. Often in evolution, natural selection will favor one trend for a number of generations, followed by a stabilization or even a return to the opposite trend. In the United States, selection for height appears to have occurred several centuries ago, leading to taller men, and then it stopped. "Perhaps the Dutch caught up and actually overshot the American men," he says.

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Huge Alien Planet Bathes in the Light of Four Suns



30 Ari with its newly discovered companion stars
Karen Teramura

Excerpt from nbcnews.com


Astronomers have spotted a fourth star in a planetary system called 30 Ari, bringing the number of known planet-harboring quadruple-sun systems to two. 

"Star systems come in myriad forms. There can be single stars, binary stars, triple stars, even quintuple star systems," study lead author Lewis Roberts, of NASA's Jet Propulsion Laboratory, said in a statement. "It's amazing the way nature puts these things together." 

30 Ari lies 136 light-years from the sun in the constellation Aries. Astronomers discovered a giant planet in the system in 2009; the world is about 10 times more massive than Jupiter and orbits its primary star every 335 days. There's also a pair of stars that lie approximately 1,670 astronomical units away. (One AU is the distance between Earth and the sun — about 93 million miles, or 150 million kilometers).

The newfound star circles its companion once every 80 years, at a distance of just 22 AU, but it does not appear to affect the exoplanet's orbit despite such proximity. This is a surprising result that will require further observations to understand, researchers said. 

To a hypothetical observer cruising through the giant planet's atmosphere, the sky would appear to host one small sun and two bright stars visible in daylight. With a large enough telescope, one of the bright stars could be resolved into a binary pair. 

The discovery marks just the second time a planet has been identified in a four-star system. The first four-star planet, PH1b or Kepler-64b, was spotted in 2012 by citizen scientists using publicly available data from NASA's Kepler mission. 

Planets with multiple suns have become less of a novelty in recent years, as astronomers have found a number of real worlds that resemble Tatooine, Luke Skywalker's home planet in the Star Wars films. 

The research was published online this month in the Astronomical Journal.

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Science of frustrated magnets: Hall Effect experiment reveals clues to their discontent

Excerpt from thewestsidestory.netA scientific study carried out in Princeton has brought about the discovery of unlikely properties in materials called frustrated magnets using the Hall Effect.Hall Effect is the property of magnetic fields having inf...

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Discovered: A ‘Treasure Chest’ of Ancient Galaxies


full sky planck
The full visible sky as seen by the Planck space observatory. The band running through the middle corresponds to dust in our Milky Way galaxy. The black dots indicate the location of the proto-cluster candidates identified by Planck and subsequently observed by the Herschel space telescope. (Photo : ESA and the Planck Collaboration)


Excerpt from natureworldnews.com

Treasure seekers have found the haul of a lifetime, but it wasn't in some ancient temple or mysterious island. Instead, it was in the sky. Researcher using two of the European Space Agency's (ESA) impressive space telescopes have successfully identified what they are calling a "treasure chest" of ancient galaxy clusters, which could help explain how the Universe came to be the way it is today.

That's at least according to a study recently published (PDF) in the journal Astronomy and Astrophysics, which details how cosmologists used the ESA's Planck space observatory to identify the distant precursor galaxy clusters, and then poured over data from the Herschel telescope for a closer look.

"Finding so many intensely star-forming, dust galaxies in such concentrated groups was a huge surprise," Hervé Dole, lead author of the report from the Institut d'Astrophysique Spatiale in France, said in a statement. "We think this is a missing piece of cosmological structure formation."

So what does he mean by that? Let's turn back to the treasure chest metaphor for this one.  While Planck was the space observatory to dig up the chest, it was the Herschel data that allowed experts to look closely at each and every gold coin (galaxy cluster) inside. Now they are able to learn more about each coin's make, mint, and ultimately, its origins.

And that's a big step in better understanding the early Universe. Expects believe that it took a great deal of time after star and galaxies first sprung to life for them to assemble into large clusters. 

A summary of the 14 billion years out Universe has been in existence, as seen by the Plank space telescop. Light coming from some of the oldest parts of the Universe are just reaching the observatory now, allowing for experts to see the incredible uniformity of the early structure, compared to the chaotic beautify of star, galaxy, and cluster formation that crowd space today.
(Photo : ESA – C. Carreau) A summary of the 14 billion years out Universe has been in existence, as seen by the Plank space telescope. Light coming from some of the oldest parts of the Universe are just reaching the observatory now, allowing for experts to see the incredible uniformity of the early matter, compared to the chaotic beautify of star, galaxy, and cluster formation that crowds space today.
Once the clusters formed, their gravitational influence triggered the creation of new stars and galaxies. Dark matter - which is theorized to account for a great deal of each cluster's mass and influence - helped usher along the process of creating stars. But how these large clusters were ultimately assembled and grew is still a mystery.
That's why looking at some of the oldest 'coins' ever made - estimated to date back to up-to 11 billion light-years ago - could be exceptionally helpful.

"We still have a lot to learn about this new population," Dole said in an ESA release. "Hints of these kinds of objects had been found earlier in data from Herschel and other telescopes, but the all-sky capability of Planck revealed many more candidates for us to study."

"Even when we combined the powerful capabilities of Planck and Herschel, we were only scratching the surface of the phenomena taking place at this critical era in the history of our universe, when stars, galaxies and clusters seem to be forming simultaneously," 
added George Helou, director of the Infrared Processing and Analysis Center at the California Institute of Technology in Pasadena. "That's one of the reasons this finding is exciting. It shows us that there is so much more to be learned.

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Hypatia, Ancient Alexandria’s Great Female Scholar

An avowed paganist in a time of religious strife, Hypatia was also one of the first women to study math, astronomy and philosophy On the streets of Alexandria, Egypt, a mob led by Peter the Lector brutally murdered Hypatia, one of the last great thinkers of ancient Alexandria. (Mary Evans Picture Library / Alamy) By Sarah Zielinskismithsonian.com One day on the streets of Alexandria, Egypt, in the year 415 or 416, a mob of Christian zealots led by Peter the Lector accosted a wom [...]

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Scientists Take Key Step to Resurrecting Extinct Woolly Mammoth; First Mammoth Could be Born in 2018

Excerpt from en.yibada.comScientists from Harvard University announced their success in splicing DNA from the extinct woolly mammoth into living cells of an Asian elephant, making it possible to "de-extinct" the animal that died-off 4,000 years ago....

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