Tag: knowledge (page 2 of 12)

The Class-Domination Theory of Power

by G. William DomhoffNOTE: WhoRulesAmerica.net is largely based on my book,Who Rules America?, first published in 1967 and now in its7th edition. This on-line document is presented as a summary of some of the main ideas in that book.Who has predominant power in the United States? The short answer, from 1776 to the present, is: Those who have the money -- or more specifically, who own income-producing land and businesses -- have the power. George Washington was one of the biggest landowner [...]

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Flawed Medical Research May Be Ruining Your Health & Your Life

Robert Oliva, Collective-EvolutionThere is a cancer eating at the core of medical research.You’ve most likely heard of medical reports touting the effectiveness of a diet plan, a new drug, a supplement, or medical procedure. You may have even decided on a course of action based on these findings, only to find out later that they have been refuted by new studies.Strikingly, the odds are that the studies that influenced your decision, and possibly the decision of your doctor, wer [...]

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Quantum Entanglement Verified: Why Space Is Just The Construct That Gives The Illusion Of Separate Objects

“Space is just the construct that gives the illusion that there are separate objects” – Dr. Quantum (see video below)There is a phenomenon so strange, so fascinating, and so counter to what we believe to be the known scientific laws of the universe, that Einstein himself could not wrap his head around it. It’s called “quantum entanglement,” though Einstein referred to it as “spooky action at a distance.”An [...]

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Lab for genetic modification of human embryos just $2,000 away – report


Reuters / Christian Charisius



Reuters

With the right expertise in molecular biology, one could start a basic laboratory to modify human embryos using a genome-editing computer technique all for a couple thousand dollars, according to a new report.

Genetic modification has received heightened scrutiny recently following last week’s announcement that Chinese researchers had, for the first time, successfully edited human embryos’ genomes. 
The team at Sun Yat-Sen University in Guangzhou, China, used CRISPR (clustered regularly interspaced palindromic repeats), a technique that relies on “cellular machinery” used by bacteria in defense against viruses. 

This machinery is copied and altered to create specific gene-editing complexes, which include the wonder enzyme Cas9. The enzyme works its way into the DNA and can be used to alter the molecule from the inside. The combination is attached to an RNA guide that takes the gene-editing complex to its target, telling Cas9 where to operate. 

Use of the CRISPR technique is not necessarily relegated to the likes of cash-flush university research operations, according to a report by Business Insider. 


Geneticist George Church, who runs a top CRISPR research program at the Harvard Medical School, said the technique could be employed with expert knowledge and about half of the money needed to pay for an average annual federal healthcare plan in 2014 -- not to mention access to human embryos. 

"You could conceivably set up a CRISPR lab for $2,000,” he said, according to Business Insider. 

Other top researchers have echoed this sentiment. 

"Any scientist with molecular biology skills and knowledge of how to work with [embryos] is going to be able to do this,” Jennifer Doudna, a biologist at the University of California, Berkeley, recently told MIT Tech Review, which reported that Doudna co-discovered how to edit genetic code using CRISPR in 2012. 

Last week, the Sun Yat-Sen University research team said it attempted to cure a gene defect that causes beta-thalassemia (a genetic blood disorder that could lead to severe anemia, poor growth, skeletal abnormalities and even death) by editing the germ line. For that purpose they used a gene-editing technique based on injecting non-viable embryos with a complex, which consists of a protective DNA element obtained from bacteria and a specific protein. 

"I suspect this week will go down as a pivotal moment in the history of medicine," wrote science journalist Carl Zimmer for National Geographic.


Response to the new research has been mixed. Some experts say the gene editing could help defeat genetic diseases even before birth. Others expressed concern. 

“At present, the potential safety and efficacy issues arising from the use of this technology must be thoroughly investigated and understood before any attempts at human engineering are sanctioned, if ever, for clinical testing,” a group of scientists, including some who had worked to develop CRISPR, warned in Science magazine. 

Meanwhile, the director of the US National Institutes for Health (NIH) said the agency would not fund such editing of human embryo genes. 

“Research using genomic editing technologies can and are being funded by NIH,” Francis Collins said Wednesday. “However, NIH will not fund any use of gene-editing technologies in human embryos. The concept of altering the human germline in embryos for clinical purposes ... has been viewed almost universally as a line that should not be crossed.”

Although the discovery of CRISPR sequences dates back to 1987 – when it was first used to cure bacteria of viruses – its successes in higher animals and humans were only achieved in 2012-13, when scientists achieved a revolution by combining the resulting treatment system with Cas9 for the first time. 


On April 17, the MIT’s Broad Institute announced that has been awarded the first-ever patent for working with the Crisp-Cas9 system. 

The institute’s director, Eric Lander, sees the combination as “an extraordinary, powerful tool. The ability to edit a genome makes it possible to discover the biological mechanisms underlying human biology.”

The system’s advantage over other methods is in that it can also target several genes at the same time, working its way through tens of thousands of so-called 'guide' RNA sequences that lead them to the weapon to its DNA targets. 

Meanwhile, last month in the UK, a healthy baby was born from an embryo screened for genetic diseases, using karyomapping, a breakthrough testing method that allows doctors to identify about 60 debilitating hereditary disorders.

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New Light on Our Accelerating Universe –"Not as Fast as We Thought"

 A Type Ia supernova, SN1994D, is shown exploding in lower left corner of the image at the top of the page of the galaxy NGC 4526 taken by the Hubble Space Telescope. (High-Z Supernova Search Team, HST, NASA)Excerpt from dailygalaxy.com Cer...

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New research shows Universe expansion pace isn’t as fast as assumed earlier



universe


Excerpt from thewestsidestory.net

The Universe is expanding and any student of astronomy will vouch to this fact. However according to a team of astronomers the acceleration of the universe may not be as quick as it was assumed earlier.

A team of astronomers have discovered that certain types of supernova are more varied than earlier thought of and in the process have led to the biggest mystery of the universe-how fast is the universe expanding after the big bang?

Peter A. Milne of the University of Arizona said, “We found that the differences are not random, but lead to separating Ia supernovae into two groups, where the group that is in the minority near us are in the majority at large distances — and thus when the universe was younger, there are different populations out there, and they have not been recognized. The big assumption has been that as you go from near to far, type Ia supernovae are the same. That doesn’t appear to be the case.”
The discovery throws new light on the currently accepted view of the universe expanding at a faster and faster rate pulled apart by an unknown force called dark energy this observation resulted in 2011 Nobel Prize for Physics.
Milne said, “The idea behind this reasoning, is that type Ia supernovae happen to be the same brightness — they all end up pretty similar when they explode. Once people knew why, they started using them as mileposts for the far side of the universe.The faraway supernovae should be like the ones nearby because they look like them, but because they’re fainter than expected, it led people to conclude they’re farther away than expected, and this in turn has led to the conclusion that the universe is expanding faster than it did in the past.”
The researchers felt that the accelerating universe can be explained on the basis of color difference in between two groups of supernova leaving less acceleration than earlier assumed and in the process will require lesser dark energy.

Milne said, “We’re proposing that our data suggest there might be less dark energy than textbook knowledge, but we can’t put a number on it, until our paper, the two populations of supernovae were treated as the same population. To get that final answer, you need to do all that work again, separately for the red and for the blue population.

Type la supernovae are considered as a benchmark for far away sources of light they do have a fraction of variability which has limited our knowledge of the size of the universe.
The distance of objects with the aid of our binocular vision and the best space-based telescopes and most sophisticated techniques works out in the range of ten or twenty thousand light years. 
However as compared to the vastness of space, this is just pea nuts.
For Distances greater than that it is imperative to compare the absolute and observed brightness of well understood objects and to use the difference to determine the object’s distance.

In astronomy it is difficult to find an object of known brightness since there are examples of both bright and dim stars and galaxies. However there is one event which can be used to work out its absolute brightness. Supernovas are the final stages of a dying star and it explodes with such violence, the flash can be seen across the vast universe.

Type la Supernovae occurs in a binary star system when a white dwarf scoops off mass from its fellow star. This reproducible mechanism gives a well determined brightness and therefore scientists term such Type la supernovae as ‘standard candles’.

Astronomers found that the Type la supernovae is so uniform that it has been designated as cosmic beacons and used to assess the depths of the universe. It is now revealed that they fall into different populations and are not very uniform as previously thought. .

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MRSA superbug killed by 1,100-year-old home remedy, researchers say


MRSA attacks a human cell. The bacteria shown is the strain MRSA 252, a leading cause of hospital-associated infections. (Rocky Mountain Laboratories, NIAID, NIH)


Excerpt from washingtonpost.com
By Justin Wm. Moyer 

Even in the age of AIDS, avian flu and Ebola, methicillin-resistant Staphylococcus aureus, better known as MRSA, is terrifying.

The superbug, which is resistant to conventional antibiotics because of their overuse, shrugs at even the deadliest weapons modern medicine offers. The Centers for Disease Control and Prevention estimated MRSA contributed to the deaths of more than 5,000 people in the United States in 2013. It even attacked the NFL, and some say it could eventually kill more people than cancer. And presidential commissions have advised that technological progress is the only way to fight MRSA.

But researchers in the United Kingdom now report that the superbug proved vulnerable to an ancient remedy. The ingredients? Just a bit of garlic, some onion or leek, copper, wine and oxgall — a florid name for cow’s bile.

This medicine sounds yucky, but it’s definitely better than the bug it may be able to kill.

“We were absolutely blown away by just how effective the combination of ingredients was,” Freya Harrison of the University of Nottingham, who worked on the research, told the BBC.

The oxgall remedy, billed as an eye salve, was found in a manuscript written in Old English from the 10th century called “Bald’s Leechbook” — a sort of pre-Magna Carta physician’s desk reference. Garlic and copper are commonly thought to have antibiotic or antimicrobial properties, but seeing such ingredients in a home remedy at Whole Foods is a far cry from researchers killing a superbug with it.

According to Christina Lee, an associate professor in Viking studies at Nottingham, the MRSA research was the product of conversations among academics of many stripes interested in infectious disease and how people fought it before antibiotics.

“We were talking about the specter of antibiotic resistance,” she told The Washington Post in a phone interview. The medical researchers involved in the discussions said to the medievalists: “In your period, you guys must have had something.”

Not every recipe in Bald’s Leechbook is a gem. Other advice, via a translation from the Eastern Algo-Saxonist: “Against a woman’s chatter; taste at night fasting a root of radish, that day the chatter cannot harm thee.” And: “In case a man be a lunatic; take skin of a mereswine or porpoise, work it into a whip, swinge the man therewith, soon he will be well. Amen.”

Though the Leechbook may include misses, it may help doctors find a solution to a problem that only seems to be getting worse.

If the oxgall remedy proves effective against MRSA outside of the lab — which researchers caution it may not — it would be a godsend. Case studies of MRSA’s impact from the CDC’s charmingly named Morbidity and Mortality Weekly Report seem medieval.

In July 1997, a 7-year-old black girl from urban Minnesota was admitted to a tertiary-care hospital with a temperature of 103 F.” Result: Death from pulmonary hemorrhage after five weeks of hospitalization.

In January 1998, a 16-month-old American Indian girl from rural North Dakota was taken to a local hospital in shock and with a temperature of 105.2 F.” Result: After respiratory failure and cardiac arrest, death within two hours of hospital admission.

In January 1999, a 13-year-old white girl from rural Minnesota was brought to a local hospital with fever, hemoptysis” — that’s coughing up blood — “and respiratory distress.” The result: Death from multiple organ failure after seven days in the hospital.

“We believe modern research into disease can benefit from past responses and knowledge, which is largely contained in non-scientific writings,” Lee told the Telegraph. “But the potential of these texts to contribute to addressing the challenges cannot be understood without the combined expertise of both the arts and science.”

Lee stressed that it was the combination of ingredients that proved effective against MRSA — which shows that people living in medieval times were not as barbaric as popularly thought. Even 1,000 years ago, when people got sick, other people tried to figure out how to help.

“We associate ‘medieval’ with dark, barbaric,” Lee said. “… It’s not. I’ve always believed in the pragmatic medieval ages.”
The research will be presented at the Annual Conference of the Society for General Microbiology in Birmingham. In an abstract for the conference, the team cautioned oxgall was no cure-all.

“Antibacterial activity of a substance in laboratory trials does not necessarily mean the historical remedy it was taken from actually worked in toto,” they wrote.

Lee said researchers hope to turn to other remedies in Bald’s Leechbook — including purported cures for headaches and ulcers — to see what other wisdom the ancients have to offer.

“At a time when you don’t have microscope, medicine would have included things we find rather odd,” she said. “In 200 years, people will judge us.”

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The Story of Human Evolution Now Challenged



Story of Human Evolution Challenged


Excerpt from newhistorian.com

The history of the evolution of early humans has been challenged.
Until now, one of the most dominant theories about our evolution claimed that our genus, Homo, had evolved from smaller early humans becoming taller, heavier and longer-legged. This process eventually resulted in Homo erectus, which was able to migrate out of Africa and colonise Eurasia.

Whilst we know that small-bodied H. erectus, averaging less than five feet tall and weighing under 50 kilograms, were living in southern Europe by 1.77 million years ago, the origin of the larger body size associated with modern humans has been elusive.

The paucity of knowledge about the origins of larger members of the Homo genus is primarily a result of a lack of evidence. Previous estimates of body size had been based on well-preserved specimens which were easy to assign a species to. Since these samples are rare and disparate in terms of both space and time, little is known about geographical and chronological variation in the body sizes of the early Homo.

A joint study between the Universities of Cambridge and Tübingen has shown that increases in body size occurred thousands of years after H. erectus left Africa; this growth in Homo body sizes primarily took place in the Koobi Fora region in modern Kenya.

“The evolution of larger bodies and longer legs can thus no longer be assumed to be the main driving factor behind the earliest excursions of our genus to Eurasia,” said Manuel Will, co-author of the study which has been published in the Journal of Human Evolution.

By using tiny fragments of fossil, the team were able to estimate our earliest ancestors’ height and body mass. Their findings, rather surprisingly, indicate a huge diversity in body size; this is particularly surprising as the wide variation we see in humans today was thought to be a relatively recent development.

“If someone asked you ‘are modern humans 6 foot tall and 70kg?’ you’d say ‘well some are, but many people aren’t,’ and what we’re starting to show is that this diversification happened really early in human evolution,” said Dr Jay Stock, co-author of the study.

Stock and Will are the first scientists in 20 years to compare the body size of humans from between 2.5 and 1.5 million years ago. They are also the first to use fragmentary fossils – many as small as toes, none longer than 5cm – to estimate body sizes.

By comparing measurements of fossils from sites in Kenya, Tanzania, South Africa and Georgia, the researchers have revealed substantial regional variation in the size of early humans. Groups who lived in South African caves, for example, were 4.8 feet tall on average. Some of the skeletons found in Kenya’s Koobi Fora region would have stood nearly 6 feet tall, a height comparable to the average height of modern British males.
“Basically every textbook on human evolution gives the perspective that one lineage of humans evolved larger bodies before spreading beyond Africa. But the evidence for this story about our origins and the dispersal out of Africa just no longer really fits,” said Stock.

It appears that Stock and Will have rewritten the history of the development of early humans; diversity has deep roots amongst the Homo genus.

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New spin on Saturn’s peculiar, err, spin

 Excerpt from spacedaily.comAccording to the new method, Saturn's day is 10 hours, 32 minutes and 44 seconds long. Tracking the rotation speed of solid planets, like the Earth and Mars, is a relatively simple task: Just measure the time it tak...

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If the Moon Landings Were Real, Then Why is NASA Stumped by This?

Buck Rogers, Staff WriterWaking TimesDuring the cold war era the Soviet Union and the United States were locked in an arms and technology race, each nation wanting to prove their dominance over the other, each striving to be the next reigning superpower in a world still shattered by the second world war. The Soviet’s took the lead when in April of 1961, cosmonaut Yuri Gagarin successfully orbited the earth and returned home safely. In May, president John F. Kennedy ma [...]

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How Quantum Physics will change your life and amaze the world!

 Excerpt from educatinghumanity.com "Anyone not shocked by quantum mechanics has not yet understood it."Niels Bohr10 Ways Quantum Physics Will Change the WorldEver want to have a "life do over", teleport, time travel, have your computer wor...

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Biologists fear DNA editing procedure can alter human DNA




Excerpt from themarketbusiness.com

A group of biologists was alarmed with the use a new genome-editing technique to modify human DNA in a way that it can become hereditary.
The biologists worry that the new technique is so effective and easy to use that some physicians may push ahead with it before its safety can be weigh up. They also want the public to understand the ethical issues surrounding the technique, which could be used to cure genetic diseases, but also to enhance qualities like beauty or intelligence. The latter is a path that many ethicists believe should never be taken.


“You could exert control over human heredity with this technique, and that is why we are raising the issue,” said David Baltimore, a former president of the California Institute of Technology and a member of the group whose paper on the topic was published in the journal Science.

Ethicists have been concerned for decades about the dangers of altering the human germ line — meaning to make changes to human sperm, eggs or embryos that will last through the life of the individual and be passed on to future generations. Until now, these worries have been theoretical. But a technique invented in 2012 makes it possible to edit the genome precisely and with much greater ease. The technique has already been used to edit the genomes of mice, rats and monkeys, and few doubt that it would work the same way in people.

The new genome-editing technique holds the power to repair or enhance any human gene. “It raises the most fundamental of issues about how we are going to view our humanity in the future and whether we are going to take the dramatic step of modifying our own germline and in a sense take control of our genetic destiny, which raises enormous peril for humanity,” said George Daley, a stem cell expert at Boston Children’s Hospital and a member of the group.

The biologists writing in Science support continuing laboratory research with the technique, and few if any scientists believe it is ready for clinical use. Any such use is tightly regulated in the United States and Europe. American scientists, for instance, would have to present a plan to treat genetic diseases in the human germline to the Food and Drug Administration.

The paper’s authors, however, are concerned about countries that have less regulation in science. They urge that “scientists should avoid even attempting, in lax jurisdictions, germ line genome modification for clinical application in humans” until the full implications “are discussed among scientific and governmental organizations.”

Though such a moratorium would not be legally enforceable and might seem unlikely to exert global sway, there is a precedent. In 1975, scientists worldwide were asked to refrain from using a method for manipulating genes, the recombinant DNA technique, until rules had been established.

“We asked at that time that nobody do certain experiments, and in fact nobody did, to my knowledge,” said Baltimore, who was a member of the 1975 group. “So there is a moral authority you can assert from the U.S., and that is what we hope to do.”

Recombinant DNA was the first in a series of ever-improving steps for manipulating genetic material. The chief problem has always been one of accuracy, of editing the DNA at precisely the intended site, since any off-target change could be lethal. Two recent methods, known as zinc fingers and TAL effectors, came close to the goal of accurate genome editing, but both are hard to use. The new genome-editing approach was invented by Jennifer Doudna of the University of California, Berkeley, and Emmanuelle Charpentier of Umea University in Sweden.

Their method, known by the acronym Crispr-Cas9, co-opts the natural immune system with which bacteria remember the DNA of the viruses that attack them so they are ready the next time those same invaders appear. Researchers can simply prime the defense system with a guide sequence of their choice and it will then destroy the matching DNA sequence in any genome presented to it. Doudna is the lead author of the Science article calling for control of the technique and organized the meeting at which the statement was developed.

Though highly efficient, the technique occasionally cuts the genome at unintended sites. The issue of how much mistargeting could be tolerated in a clinical setting is one that Doudna’s group wants to see thoroughly explored before any human genome is edited.

Scientists also say that replacing a defective gene with a normal one may seem entirely harmless but perhaps would not be.
“We worry about people making changes without the knowledge of what those changes mean in terms of the overall genome,” Baltimore said. “I personally think we are just not smart enough — and won’t be for a very long time — to feel comfortable about the consequences of changing heredity, even in a single individual.”
Many ethicists have accepted the idea of gene therapy, changes that die with the patient, but draw a clear line at altering the germline, since these will extend to future generations. The British Parliament in February approved the transfer of mitochondria, small DNA-containing organelles, to human eggs whose own mitochondria are defective. But that technique is less far-reaching because no genes are edited.

There are two broad schools of thought on modifying the human germline, said R. Alta Charo, a bioethicist at the University of Wisconsin and a member of the Doudna group. One is pragmatic and seeks to balance benefit and risk. The other “sets up inherent limits on how much humankind should alter nature,” she said. 
Some Christian doctrines oppose the idea of playing God, whereas in Judaism and Islam there is the notion “that humankind is supposed to improve the world.” She described herself as more of a pragmatist, saying, “I would try to regulate such things rather than shut a new technology down at its beginning.”

Other scientists agree with the Doudna group’s message.
“It is very clear that people will try to do gene editing in humans,” said Rudolf Jaenisch, a stem cell biologist at the Whitehead Institute in Cambridge, Massachusetts, who was not a member of the Doudna group. “This paper calls for a moratorium on any clinical application, which I believe is the right thing to do.”
Writing in Nature last week, Edward Lanphier and other scientists involved in developing the rival zinc finger technique for genome editing also called for a moratorium on human germline modification, saying that use of current technologies would be “dangerous and ethically unacceptable.”

The International Society for Stem Cell Research said Thursday that it supported the proposed moratorium.

The Doudna group calls for public discussion but is also working to develop some more formal process, such as an international meeting convened by the National Academy of Sciences, to establish guidelines for human use of the genome-editing technique.

“We need some principled agreement that we want to enhance humans in this way or we don’t,” Jaenisch said. “You have to have this discussion because people are gearing up to do this.”

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Does the Past Exist Yet? Evidence Suggests Your Past Isn’t Set in Stone


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Excerpt from robertlanza.com
By Robert Lanza 

Recent discoveries require us to rethink our understanding of history. “The histories of the universe,” said renowned physicist Stephen Hawking “depend on what is being measured, contrary to the usual idea that the universe has an objective observer-independent history.”

Is it possible we live and die in a world of illusions? Physics tells us that objects exist in a suspended state until observed, when they collapse in to just one outcome. Paradoxically, whether events happened in the past may not be determined until sometime in your future – and may even depend on actions that you haven’t taken yet.

In 2002, scientists carried out an amazing experiment, which showed that particles of light “photons” knew — in advance — what their distant twins would do in the future. They tested the communication between pairs of photons — whether to be either a wave or a particle. Researchers stretched the distance one of the photons had to take to reach its detector, so that the other photon would hit its own detector first. The photons taking this path already finished their journeys — they either collapse into a particle or don’t before their twin encounters a scrambling device.
Somehow, the particles acted on this information before it happened, and across distances instantaneously as if there was no space or time between them. They decided not to become particles before their twin ever encountered the scrambler. It doesn’t matter how we set up the experiment. Our mind and its knowledge is the only thing that determines how they behave. Experiments consistently confirm these observer-dependent effects.

More recently (Science 315, 966, 2007), scientists in France shot photons into an apparatus, and showed that what they did could retroactively change something that had already happened. As the photons passed a fork in the apparatus, they had to decide whether to behave like particles or waves when they hit a beam splitter. 
Later on – well after the photons passed the fork – the experimenter could randomly switch a second beam splitter on and off. It turns out that what the observer decided at that point, determined what the particle actually did at the fork in the past. At that moment, the experimenter chose his history.

Of course, we live in the same world. Particles have a range of possible states, and it’s not until observed that they take on properties. So until the present is determined, how can there be a past? According to visionary physicist John Wheeler (who coined the word “black hole”), “The quantum principle shows that there is a sense in which what an observer will do in the future defines what happens in the past.” Part of the past is locked in when you observe things and the “probability waves collapse.” But there’s still uncertainty, for instance, as to what’s underneath your feet. If you dig a hole, there’s a probability you’ll find a boulder. Say you hit a boulder, the glacial movements of the past that account for the rock being in exactly that spot will change as described in the Science experiment.

But what about dinosaur fossils? Fossils are really no different than anything else in nature. For instance, the carbon atoms in your body are “fossils” created in the heart of exploding supernova stars. 
Bottom line: reality begins and ends with the observer. “We are participators,” Wheeler said “in bringing about something of the universe in the distant past.” Before his death, he stated that when observing light from a quasar, we set up a quantum observation on an enormously large scale. It means, he said, the measurements made on the light now, determines the path it took billions of years ago.

Like the light from Wheeler’s quasar, historical events such as who killed JFK, might also depend on events that haven’t occurred yet. There’s enough uncertainty that it could be one person in one set of circumstances, or another person in another. Although JFK was assassinated, you only possess fragments of information about the event. But as you investigate, you collapse more and more reality. According to biocentrism, space and time are relative to the individual observer – we each carry them around like turtles with shells.

History is a biological phenomenon — it’s the logic of what you, the animal observer experiences. You have multiple possible futures, each with a different history like in the Science experiment. Consider the JFK example: say two gunmen shot at JFK, and there was an equal chance one or the other killed him. This would be a situation much like the famous Schrödinger’s cat experiment, in which the cat is both alive and dead — both possibilities exist until you open the box and investigate.

“We must re-think all that we have ever learned about the past, human evolution and the nature of reality, if we are ever to find our true place in the cosmos,” says Constance Hilliard, a historian of science at UNT. Choices you haven’t made yet might determine which of your childhood friends are still alive, or whether your dog got hit by a car yesterday. In fact, you might even collapse realities that determine whether Noah’s Ark sank. “The universe,” said John Haldane, “is not only queerer than we suppose, but queerer than we can suppose.”

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