Tag: humankind (page 1 of 2)

The World’s Food Seeds are Going Extinct, but You Can Help

Alex Pietrowski, Staff WriterMost of the truly important news of our times goes unnoticed, under-reported or ignored by the corporate media, and as they focus on the ever-evolving narrative of human political drama, we are missing opportunities to participate in the most important struggles of our time. Seven generations from now, the destruction of the world’s seed diversity by corporate greed will have a much greater impact on the human condition than as much as any [...]

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Biologists fear DNA editing procedure can alter human DNA




Excerpt from themarketbusiness.com

A group of biologists was alarmed with the use a new genome-editing technique to modify human DNA in a way that it can become hereditary.
The biologists worry that the new technique is so effective and easy to use that some physicians may push ahead with it before its safety can be weigh up. They also want the public to understand the ethical issues surrounding the technique, which could be used to cure genetic diseases, but also to enhance qualities like beauty or intelligence. The latter is a path that many ethicists believe should never be taken.


“You could exert control over human heredity with this technique, and that is why we are raising the issue,” said David Baltimore, a former president of the California Institute of Technology and a member of the group whose paper on the topic was published in the journal Science.

Ethicists have been concerned for decades about the dangers of altering the human germ line — meaning to make changes to human sperm, eggs or embryos that will last through the life of the individual and be passed on to future generations. Until now, these worries have been theoretical. But a technique invented in 2012 makes it possible to edit the genome precisely and with much greater ease. The technique has already been used to edit the genomes of mice, rats and monkeys, and few doubt that it would work the same way in people.

The new genome-editing technique holds the power to repair or enhance any human gene. “It raises the most fundamental of issues about how we are going to view our humanity in the future and whether we are going to take the dramatic step of modifying our own germline and in a sense take control of our genetic destiny, which raises enormous peril for humanity,” said George Daley, a stem cell expert at Boston Children’s Hospital and a member of the group.

The biologists writing in Science support continuing laboratory research with the technique, and few if any scientists believe it is ready for clinical use. Any such use is tightly regulated in the United States and Europe. American scientists, for instance, would have to present a plan to treat genetic diseases in the human germline to the Food and Drug Administration.

The paper’s authors, however, are concerned about countries that have less regulation in science. They urge that “scientists should avoid even attempting, in lax jurisdictions, germ line genome modification for clinical application in humans” until the full implications “are discussed among scientific and governmental organizations.”

Though such a moratorium would not be legally enforceable and might seem unlikely to exert global sway, there is a precedent. In 1975, scientists worldwide were asked to refrain from using a method for manipulating genes, the recombinant DNA technique, until rules had been established.

“We asked at that time that nobody do certain experiments, and in fact nobody did, to my knowledge,” said Baltimore, who was a member of the 1975 group. “So there is a moral authority you can assert from the U.S., and that is what we hope to do.”

Recombinant DNA was the first in a series of ever-improving steps for manipulating genetic material. The chief problem has always been one of accuracy, of editing the DNA at precisely the intended site, since any off-target change could be lethal. Two recent methods, known as zinc fingers and TAL effectors, came close to the goal of accurate genome editing, but both are hard to use. The new genome-editing approach was invented by Jennifer Doudna of the University of California, Berkeley, and Emmanuelle Charpentier of Umea University in Sweden.

Their method, known by the acronym Crispr-Cas9, co-opts the natural immune system with which bacteria remember the DNA of the viruses that attack them so they are ready the next time those same invaders appear. Researchers can simply prime the defense system with a guide sequence of their choice and it will then destroy the matching DNA sequence in any genome presented to it. Doudna is the lead author of the Science article calling for control of the technique and organized the meeting at which the statement was developed.

Though highly efficient, the technique occasionally cuts the genome at unintended sites. The issue of how much mistargeting could be tolerated in a clinical setting is one that Doudna’s group wants to see thoroughly explored before any human genome is edited.

Scientists also say that replacing a defective gene with a normal one may seem entirely harmless but perhaps would not be.
“We worry about people making changes without the knowledge of what those changes mean in terms of the overall genome,” Baltimore said. “I personally think we are just not smart enough — and won’t be for a very long time — to feel comfortable about the consequences of changing heredity, even in a single individual.”
Many ethicists have accepted the idea of gene therapy, changes that die with the patient, but draw a clear line at altering the germline, since these will extend to future generations. The British Parliament in February approved the transfer of mitochondria, small DNA-containing organelles, to human eggs whose own mitochondria are defective. But that technique is less far-reaching because no genes are edited.

There are two broad schools of thought on modifying the human germline, said R. Alta Charo, a bioethicist at the University of Wisconsin and a member of the Doudna group. One is pragmatic and seeks to balance benefit and risk. The other “sets up inherent limits on how much humankind should alter nature,” she said. 
Some Christian doctrines oppose the idea of playing God, whereas in Judaism and Islam there is the notion “that humankind is supposed to improve the world.” She described herself as more of a pragmatist, saying, “I would try to regulate such things rather than shut a new technology down at its beginning.”

Other scientists agree with the Doudna group’s message.
“It is very clear that people will try to do gene editing in humans,” said Rudolf Jaenisch, a stem cell biologist at the Whitehead Institute in Cambridge, Massachusetts, who was not a member of the Doudna group. “This paper calls for a moratorium on any clinical application, which I believe is the right thing to do.”
Writing in Nature last week, Edward Lanphier and other scientists involved in developing the rival zinc finger technique for genome editing also called for a moratorium on human germline modification, saying that use of current technologies would be “dangerous and ethically unacceptable.”

The International Society for Stem Cell Research said Thursday that it supported the proposed moratorium.

The Doudna group calls for public discussion but is also working to develop some more formal process, such as an international meeting convened by the National Academy of Sciences, to establish guidelines for human use of the genome-editing technique.

“We need some principled agreement that we want to enhance humans in this way or we don’t,” Jaenisch said. “You have to have this discussion because people are gearing up to do this.”

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Fresh fossil studies push the dawn of man back to 2.8 million years

(Reuters) - A 2.8-million-year-old jawbone fossil with five intact teeth unearthed in an Ethiopian desert is pushing back the dawn of humankind by about half a million years.Scientists said on Wednesday the fossil represents the oldest known repres...

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NASA Spacecraft Begins 1st Ever Approach To Pluto





Excerpt from 
sanfrancisco.cbslocal.com

SAN FRANCISCO (CBS SF) – Man is about to reach closer to Pluto than ever before as the NASA New Horizons spacecraft begins the first of several approach phases toward the dwarf planet at the edge of our solar system.

When the mission was in the planning phases, Pluto was still considered a planet, but in 2006 it was reclassified as a dwarf planet. That same year, the New Horizons spacecraft blasted off as the fastest ever, shooting out off on a 4.6 billion mile journey to the distant sphere.


The piano-size New Horizons craft was in a hibernation phase as it traveled the first 3 billion miles toward Pluto. It woke up last month and is now getting ready for the first photo shoot.

“NASA first mission to distant Pluto will also be humankind’s first close up view of this cold, unexplored world in our solar system,” said Jim Green, director of NASA’s Planetary Science Division at the agency’s Headquarters in Washington.

Beginning January 25th, the probe will begin snapping photos of Pluto, which is the 10th largest celestial body orbiting our sun.
The later stages of approach will require steering the craft closer to Pluto by using photo information to steer around five known moons and other potential perils.

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Scientists Unveiled the History of Human Alcohol Consumption




Excerpt from
rt.com 

Civilization has been enjoying a good tipple for much longer than we previously thought, according to a new study. In fact, it seems that our primate ancestors began getting tipsy 10 million years ago, by eating and metabolizing fermented fruit.

Until now, it was widely believed that man came into contact with alcohol around 9,000 years ago, when Chinese villagers combined fruit and honey to make an intoxicating brew.

But a new study in the Proceedings of the National Academy of Sciences claims that humankind has been boozing for much longer than believed. 

Research led by Professor Matthew Carrigan from Santa Fe College in Florida, examined the alcohol gene ADH4, “the first enzyme exposed to ethanol in the digestive tract that is capable of metabolizing ethanol,” in samples of almost 70 million years of primate evolution. Scientists were able to identify a single gene variant that enabled our kind to first break down ethanol in the digestive system – and it took place about 10 million years ago.

AFP Photo/Vincent Jannink
AFP Photo/Vincent Jannink
“The evolving catalytic properties of these resurrected enzymes show that our ape ancestors gained a digestive dehydrogenase enzyme capable of metabolizing ethanol near the time they began using the forest floor about 10 million years ago,” Professor Carrigan said, as quoted by the Mirror.
The study of the ADH4 family was reconstructed using genes from 28 different mammals, including 17 primates from public databases or DNA extracted from tissue samples.
The research found that hominins – early humans – were able to metabolise ethanol long before “human-directed fermentation.” The mutation coincided with the transition to a “terrestrial lifestyle,” when our ancestors were forced to come down from a tree and eat fermented fruits during times of food scarcity.
As fruit on ground contains higher concentrations of fermenting yeast and ethanol than fruits hanging on trees, “this transition may also be the first time our ancestors were exposed to - and adapted to - substantial amounts of dietary ethanol,” Professor Carrigan said. 

“The ADH4 enzyme in our more ancient and arboreal ancestors did not efficiently oxidize ethanol. This change suggests exposure to dietary sources of ethanol increased in hominids during the early stages of our adaptation to a terrestrial lifestyle,” he added.
This transition, Carrigan concludes, “implies the genomes of modern human, chimpanzee and gorilla began adapting...to dietary ethanol...that is remarkably similar in concentration and form...to the moderate ethanol consumption now recognised to be healthy for many humans.”

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Space Mysteries ~ Alien Safari

We use the most cutting edge theories and technologies available, top astronomers, astrophysicists and astrobiologists seek answers to the mysteries of space in our universe.Since the dawn of humankind, our species has looked to the sky in wonder an...

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Who is Jesus to Ascended Consciousness?

By: Robert Burney"Jesus was a perfect Spiritual Being, a direct extension/manifestation from the ONENESS that is the God/Goddess Energy, having a human experience - just as we all are perfect Spiritual Beings having a human experience.""This Master Teacher was known as Jesus the Christ. The man Jesus was a perfect child of the Goddess and God energy - just as we all are perfect children of the God-Force!"This messenger added the most powerful ingredient to the process. He brought us our sec [...]

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What is Enlightenment?

Thomas Razzeto, GrahamHancock.comMy most passionate plea is for you to wake up to your true self as pure awareness. We have all heard it said that you are not a human being having a spiritual experience, but instead, you are a spiritual being having a human experience. Yet you are not a being of any kind, spiritual or physical. You are pure awareness! And most importantly, your awareness is the One Awareness – the Divine Awareness – and as such, it is the only reality tha [...]

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Hollow Earth Conspiracy: The HOLE Truth

by Will Storr For centuries, Hollow Earth conspiracy theorists have tried to prove that there’s a whole other world beneath our own. But first they need to find the way in...Late at night, on October 4 2002, a strange guest appeared on a cult American radio show. Coast to Coast AM with Art Bell had a reputation for exploring weird themes with fascinating guests, but few had ever sounded as excited as this one. Dallas Thompson was a former personal trainer who had spent his [...]

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30 Life Changing Lessons to Learn from Thích Nhất Hạnh

Luminita Saviuc, Purpose FairyWhen I think of Thích Nhất Hạnh, words like – stillness, love, compassion, peace and oneness, come to mind. And even though these are some really beautiful and powerful words, they somehow can’t really express the beautiful, pure and loving feelings that I get from reading Thích Nhất Hạnh’s books and watching his beautiful videos.Thích Nhất Hạnh is someone who’s wor [...]

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Zen Gardner ~ Are You Alone? Or Strategically Placed! ~

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29 March 2012

I hear from so many people who feel isolated and alone during this awakening and massive paradigm shift taking place around the globe. Spouses can’t wake up partners to the truth; family members and close frien...

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Project Blue Beam

By Serge Monast
http://educate-yourself.org/cn/projectbluebeam25jul05.shtml
Originally Published 1994

[Note: Serge Monast [1945 – December 5, 1996] and another journalist, both of whom were researching Project Blue Beam, died of “heart attackswithin weeks of each other although neither had a history of heart disease. Serge was in Canada. The other Canadian journalist was visiting Ireland. Prior to his death, the Canadian government abducted Serge’s daughter in an attempt to dissuade him from pursuing his research into Project Blue Beam. His daughter was never returned. Pseudo-heart attacks are one of the alleged methods of death induced by Project Blue Beam.]

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Planet’s Omnipotent Strength

Excerpt of Tyberonn Channel of Metatron:

“The Earth is an omnipotent presence. The EARTH CANNOT be DESTROYED. Whether you accept it or not, NOTHING is taken from the Earth that the Earth does not ALLOW. Man cannot destroy the...

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