This is the moment that has the same historical impact and significance as the storming of the Bastille which started the French Revolution:https://en.wikipedia.org/wiki/Storming_of_the_Bastille Many pro-Trump protesters have managed to enter the ...
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By Marilyn Raffaele.
MARCH 25,2018
Greetings, dear ones. Once again we lovingly offer guidance in order to assist your evolutionary journey at this time of so much
Kyle McMillan, GuestAccording to The Business Insider, Steve Jobs only downloaded one book, ever, to his iPad 2: Autobiography of a Yogi, by Paramahansa Yogananda. To those in the know, this should come as no surprise, as it was also his parting gift to all of the attendees at his funeral — the last gesture he made towards everyone closest to him on earth. Jobs’ spirituality was not widely well-known during his life, and while many will contest that certain busi [...]
A Failed War On Cancer Sayer Ji, Green Med InfoEver since Richard Nixon officially declared a war on cancer in 1971 through the signing of the National Cancer Act, over a hundred billion dollars of taxpayer money has been spent on research and drug development in an attempt to eradicate the disease, with trillions more spent by the cancer patients themselves, but with disappointing results.Even after four decades of waging full-scale “conventional” (s [...]
Marco Torres, Prevent DiseaseCompounds within garlic produce reactive oxygen species in cancer cells, activating of multiple death cascades and blocking pathways of tumor proliferation. Eating garlic just twice per week reduces cancer risk without any side effects whatsoever.The reason so many people die with conventional cancer treatment is that while damaging healthy cells, chemotherapy also triggers them to secrete a protein that sustains tumour growth and resistance to [...]
by Ines SuljMercury has just gone retrograde again. This time in Gemini, the sign it rules.All the planets, except Sun and Moon, go in apparent backward motion from time to time, yet the Mercury retrograde seems to be the most famous one. Almost everyone knows about it, including the people who know nothing about astrology and those who don’t even believe in it.In astrology, when a planet is in retrograde, it doesn’t actually move backwards in the sky. It only a [...]
Brian Rogers, Prevent DiseaseI used to be pro vaccine. I know the feeling of thinking others were just plain crazy and wrong for not vaccinating their children and themselves. ‘Irresponsible!’ I said when pointing my finger. I’d use the same old arguments about polio and small pox and how vaccines saved us from all those horrible diseases and just swallowing and regurgitating the propaganda I was brought up with. It was only recently, in 2009 that I started question [...]
Alisa Opar, GuestThe plant world is a violent place. When munching caterpillars or grazing cattle set their sights on a luscious leaf, a plant can’t hightail it out of harm’s way. Instead, flora fight back with noxious chemicals. But what repels one critter may not work on the next hungry mouth, explains Heidi Appel, a senior research scientist in the Bond Life Sciences Center at the University of Missouri. She’s found that some plants can actual [...]
Originally Posted at in5d.com The following is the alleged result of the actions of one or more scientists creating a covert, unauthorized notebook documenting their involvement with an Above Top Secret government program. Government publications and information obtained by the use of public tax monies cannot be subject to copyright. This document is released into the public domain for all citizens of the United States of America. THE ‘MAJIC PROJECTS’ SIGMA is the project whic [...]
Excerpt from independent.co.uk
By Jordan Gaines Lewis
In neuroscience, food is something we call a “natural reward.” In order for us to survive as a species, things like eating, having sex and nurturing others must be pleasurable to the brain so that these behaviours are reinforced and repeated.
Evolution has resulted in the mesolimbic pathway, a brain system that deciphers these natural rewards for us. When we do something pleasurable, a bundle of neurons called the ventral tegmental area uses the neurotransmitter dopamine to signal to a part of the brain called the nucleus accumbens. The connection between the nucleus accumbens and our prefrontal cortex dictates our motor movement, such as deciding whether or not to taking another bite of that delicious chocolate cake. The prefrontal cortex also activates hormones that tell our body: “Hey, this cake is really good. And I’m going to remember that for the future.”Not all foods are equally rewarding, of course. Most of us prefer sweets over sour and bitter foods because, evolutionarily, our mesolimbic pathway reinforces that sweet things provide a healthy source of carbohydrates for our bodies. When our ancestors went scavenging for berries, for example, sour meant “not yet ripe,” while bitter meant “alert – poison!”
Fruit is one thing, but modern diets have taken on a life of their own. A decade ago, it was estimated that the average American consumed 22 teaspoons of added sugar per day, amounting to an extra 350 calories; it may well have risen since then. A few months ago, one expert suggested that the average Briton consumes 238 teaspoons of sugar each week.
Today, with convenience more important than ever in our food selections, it’s almost impossible to come across processed and prepared foods that don’t have added sugars for flavour, preservation, or both.
These added sugars are sneaky – and unbeknown to many of us, we’ve become hooked. In ways that drugs of abuse – such as nicotine, cocaine and heroin – hijack the brain’s reward pathway and make users dependent, increasing neuro-chemical and behavioural evidence suggests that sugar is addictive in the same way, too.
Sugar addiction is real
Anyone who knows me also knows that I have a huge sweet tooth. I always have. My friend and fellow graduate student Andrew is equally afflicted, and living in Hershey, Pennsylvania – the “Chocolate Capital of the World” – doesn’t help either of us. But Andrew is braver than I am. Last year, he gave up sweets for Lent. “The first few days are a little rough,” Andrew told me. “It almost feels like you’re detoxing from drugs. I found myself eating a lot of carbs to compensate for the lack of sugar.”There are four major components of addiction: bingeing, withdrawal, craving, and cross-sensitisation (the notion that one addictive substance predisposes someone to becoming addicted to another). All of these components have been observed in animal models of addiction – for sugar, as well as drugs of abuse.
A typical experiment goes like this: rats are deprived of food for 12 hours each day, then given 12 hours of access to a sugary solution and regular chow. After a month of following this daily pattern, rats display behaviours similar to those on drugs of abuse. They’ll binge on the sugar solution in a short period of time, much more than their regular food. They also show signs of anxiety and depression during the food deprivation period. Many sugar-treated rats who are later exposed to drugs, such as cocaine and opiates, demonstrate dependent behaviours towards the drugs compared to rats who did not consume sugar beforehand.
Like drugs, sugar spikes dopamine release in the nucleus accumbens. Over the long term, regular sugar consumption actually changes the gene expression and availability of dopamine receptors in both the midbrain and frontal cortex. Specifically, sugar increases the concentration of a type of excitatory receptor called D1, but decreases another receptor type called D2, which is inhibitory. Regular sugar consumption also inhibits the action of the dopamine transporter, a protein which pumps dopamine out of the synapse and back into the neuron after firing.
In short, this means that repeated access to sugar over time leads to prolonged dopamine signalling, greater excitation of the brain’s reward pathways and a need for even more sugar to activate all of the midbrain dopamine receptors like before. The brain becomes tolerant to sugar – and more is needed to attain the same “sugar high.”
Sugar withdrawal is also real
Although these studies were conducted in rodents, it’s not far-fetched to say that the same primitive processes are occurring in the human brain, too. “The cravings never stopped, [but that was] probably psychological,” Andrew told me. “But it got easier after the first week or so.”In a 2002 study by Carlo Colantuoni and colleagues of Princeton University, rats who had undergone a typical sugar dependence protocol then underwent “sugar withdrawal.” This was facilitated by either food deprivation or treatment with naloxone, a drug used for treating opiate addiction which binds to receptors in the brain’s reward system. Both withdrawal methods led to physical problems, including teeth chattering, paw tremors, and head shaking. Naloxone treatment also appeared to make the rats more anxious, as they spent less time on an elevated apparatus that lacked walls on either side.
Similar withdrawal experiments by others also report behaviour similar to depression in tasks such as the forced swim test. Rats in sugar withdrawal are more likely to show passive behaviours (like floating) than active behaviours (like trying to escape) when placed in water, suggesting feelings of helplessness.
A new study published by Victor Mangabeira and colleagues in this month’s Physiology & Behavior reports that sugar withdrawal is also linked to impulsive behaviour. Initially, rats were trained to receive water by pushing a lever. After training, the animals returned to their home cages and had access to a sugar solution and water, or just water alone. After 30 days, when rats were again given the opportunity to press a lever for water, those who had become dependent on sugar pressed the lever significantly more times than control animals, suggesting impulsive behaviour.
These are extreme experiments, of course. We humans aren’t depriving ourselves of food for 12 hours and then allowing ourselves to binge on soda and doughnuts at the end of the day. But these rodent studies certainly give us insight into the neuro-chemical underpinnings of sugar dependence, withdrawal, and behaviour.
Through decades of diet programmes and best-selling books, we’ve toyed with the notion of “sugar addiction” for a long time. There are accounts of those in “sugar withdrawal” describing food cravings, which can trigger relapse and impulsive eating. There are also countless articles and books about the boundless energy and new-found happiness in those who have sworn off sugar for good. But despite the ubiquity of sugar in our diets, the notion of sugar addiction is still a rather taboo topic.
Are you still motivated to give up sugar? You might wonder how long it will take until you’re free of cravings and side-effects, but there’s no answer – everyone is different and no human studies have been done on this. But after 40 days, it’s clear that Andrew had overcome the worst, likely even reversing some of his altered dopamine signalling. “I remember eating my first sweet and thinking it was too sweet,” he said. “I had to rebuild my tolerance.”
And as regulars of a local bakery in Hershey – I can assure you, readers, that he has done just that.
Jordan Gaines Lewis is a Neuroscience Doctoral Candidate at Penn State College of Medicine
Excerpt from mercurynews.comThe federal government's top communications regulator on Wednesday called for strong new rules to bar Internet and wireless providers from blocking, slowing or discriminating against consumers' access to particular websi...
Matthew Butler, GuestPeople save up for retirement, but how well do we prepare for the journey after? Ancient cultures put great emphasis on the afterlife, because they knew consciousness continued after death. They were right: Out-of-body experiences reveal we really do exist beyond the body. Knowing this truth should inspire us to seek in life what really matters and remains after death – awakened consciousness.What is the greatest mystery of life? According to a legendar [...]
by Julian RoseContributor, ZenGardner.comSpiders do it. Take a look – oh what an amazing creation! Working their way out from the first circle; filling-in every loop of the circuit; spinning on the outward pull; determined, full of intention, guided by Divine. So my friends, why can’t we?Look at that final creation on the garden gate on a misty October morning – wow – what a stunner! Stay looking and what do you see? A little universe spun into being, oh so de [...]
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