Tag: effective (page 2 of 5)

5 Reasons The Most Dangerous Drug Is Not Illegal

June 4, 2015 / / 0 Comments

Marco Torres, Prevent DiseaseHundreds of millions of people indulge in one of the most dangerous drugs which is sold right over the counter. When it comes to harm done to other people and the users themselves, not heroin, crack cocaine, methamphetamines, marijuana or even tobacco come close to the health and safety hazards caused by this one depressant.Drug harms fall into two broad categories: those that affect you, and those that affect others. The personal ones include death, heal [...]

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12 Homeopathic Remedies That Should Be in Every Survival Kit

May 27, 2015 / / 0 Comments

Bonnie Camo, MD, GuestIn the event of a natural or man-made disaster, you may be cut off from medical aid. One of the most important things to have on hand will be a homeopathy emergency survival kit. Homeopathy is cheap, effective, and has no side effects. This medical science uses natural substances to stimulate the body to heal itself. Most homeopathic remedies are made from herbs and minerals, and they are based on the principle discovered over 200 years ago in Germany by Dr. Sam [...]

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This Kind of Olive Oil Can Kill Cancer Cells in One Hour

May 26, 2015 / / 0 Comments

Karen Foster, Prevent DiseaseExtra virgin olive oil has the capacity to induce rapid death in cancer cells while leaving healthy cells intact. The many implicated health benefits of olive oil is well known, however scientists have been unable to effectively confirm the anti-cancer phenomenon until now. The processing of olive oils also highly differentiates the concentration of anti-cancer compounds.Oleocanthal (OC), a phenolic compound in extra virgin olive oil (EVOO), has been impl [...]

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7 Reasons You Need More Magnesium

May 16, 2015 / / 0 Comments

Margie King, GuestMagnesium is the fourth most abundant mineral in your body.  But few people fully appreciate this miraculous mineral. The human genome project reveals that 3,751 human proteins have binding sites for magnesium.[i]  And so far we know this one essential mineral activates over 350 biochemical processes in the body to keep things flowing.Here are just seven good reasons to get more magnesium today. 1. Prevent Migraines. According to University of Vermo [...]

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11 Common Symptoms of the Global Depopulation Slow Kill

May 13, 2015 / / 0 Comments

Sigmund Fraud, Staff Writer“Maintain humanity under 500,000,000 in perpetual balance with nature.” – The Georgia GuidestonesThe full-spectrum global attack on human health is quite obvious to see for anyone who is paying attention and in search of wellness. So many of the factors that are negatively influencing public heath could easily be prevented or removed from society, yet the decisions of the ruling class continue to ensure that our food supply [...]

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US Government Admits Americans Have Been Overdosed on Fluoride

May 12, 2015 / / 0 Comments

Dr. MercolaThe US government has finally admitted they’ve overdosed Americans on fluoride and, for first time since 1962, are lowering its recommended level of fluoride in drinking water.1,2,3About 40 percent of American teens have dental fluorosis,4 a condition referring to changes in the appearance of tooth enamel—from chalky-looking lines and splotches to dark staining and pitting—caused by long-term ingestion of fluoride during the time teeth are forming.In some areas, fluoro [...]

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Desperately Seeking ET: Fermi’s Paradox Turns 65 ~ Part 2

May 5, 2015 / / 0 Comments

Excerpt from huffingtonpost.comIntroductionWhy is it so hard to find ET? After 50 years of searching, the SETI project has so far found nothing. In the latest development, on April 14, 2015 Penn State researchers announced that after searching through...

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Desperately Seeking Extraterrestrials ~ Fermi’s Paradox Turns 65 ~ Part 1

May 4, 2015 / / 0 Comments

Excerpt from huffingtonpost.comIntroduction 65 years ago, in 1950, while having lunch with colleagues Edward Teller and Herbert York, Nobel physicist Enrico Fermi suddenly blurted out, "Where is everybody?" His question is now known as Fermi's p...

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MRSA superbug killed by 1,100-year-old home remedy, researchers say

March 31, 2015 / / 0 Comments


MRSA attacks a human cell. The bacteria shown is the strain MRSA 252, a leading cause of hospital-associated infections. (Rocky Mountain Laboratories, NIAID, NIH)


Excerpt from washingtonpost.com
By Justin Wm. Moyer 

Even in the age of AIDS, avian flu and Ebola, methicillin-resistant Staphylococcus aureus, better known as MRSA, is terrifying.

The superbug, which is resistant to conventional antibiotics because of their overuse, shrugs at even the deadliest weapons modern medicine offers. The Centers for Disease Control and Prevention estimated MRSA contributed to the deaths of more than 5,000 people in the United States in 2013. It even attacked the NFL, and some say it could eventually kill more people than cancer. And presidential commissions have advised that technological progress is the only way to fight MRSA.

 But researchers in the United Kingdom now report that the superbug proved vulnerable to an ancient remedy. The ingredients? Just a bit of garlic, some onion or leek, copper, wine and oxgall — a florid name for cow’s bile.

This medicine sounds yucky, but it’s definitely better than the bug it may be able to kill.

“We were absolutely blown away by just how effective the combination of ingredients was,” Freya Harrison of the University of Nottingham, who worked on the research, told the BBC.

The oxgall remedy, billed as an eye salve, was found in a manuscript written in Old English from the 10th century called “Bald’s Leechbook” — a sort of pre-Magna Carta physician’s desk reference. Garlic and copper are commonly thought to have antibiotic or antimicrobial properties, but seeing such ingredients in a home remedy at Whole Foods is a far cry from researchers killing a superbug with it.

 According to Christina Lee, an associate professor in Viking studies at Nottingham, the MRSA research was the product of conversations among academics of many stripes interested in infectious disease and how people fought it before antibiotics.

“We were talking about the specter of antibiotic resistance,” she told The Washington Post in a phone interview. The medical researchers involved in the discussions said to the medievalists: “In your period, you guys must have had something.”

Not every recipe in Bald’s Leechbook is a gem. Other advice, via a translation from the Eastern Algo-Saxonist: “Against a woman’s chatter; taste at night fasting a root of radish, that day the chatter cannot harm thee.” And: “In case a man be a lunatic; take skin of a mereswine or porpoise, work it into a whip, swinge the man therewith, soon he will be well. Amen.”

 Though the Leechbook may include misses, it may help doctors find a solution to a problem that only seems to be getting worse.

If the oxgall remedy proves effective against MRSA outside of the lab — which researchers caution it may not — it would be a godsend. Case studies of MRSA’s impact from the CDC’s charmingly named Morbidity and Mortality Weekly Report seem medieval.

“In July 1997, a 7-year-old black girl from urban Minnesota was admitted to a tertiary-care hospital with a temperature of 103 F.” Result: Death from pulmonary hemorrhage after five weeks of hospitalization.

“In January 1998, a 16-month-old American Indian girl from rural North Dakota was taken to a local hospital in shock and with a temperature of 105.2 F.” Result: After respiratory failure and cardiac arrest, death within two hours of hospital admission.

“In January 1999, a 13-year-old white girl from rural Minnesota was brought to a local hospital with fever, hemoptysis” — that’s coughing up blood — “and respiratory distress.” The result: Death from multiple organ failure after seven days in the hospital.

“We believe modern research into disease can benefit from past responses and knowledge, which is largely contained in non-scientific writings,” Lee told the Telegraph. “But the potential of these texts to contribute to addressing the challenges cannot be understood without the combined expertise of both the arts and science.”

Lee stressed that it was the combination of ingredients that proved effective against MRSA — which shows that people living in medieval times were not as barbaric as popularly thought. Even 1,000 years ago, when people got sick, other people tried to figure out how to help.

“We associate ‘medieval’ with dark, barbaric,” Lee said. “… It’s not. I’ve always believed in the pragmatic medieval ages.”
The research will be presented at the Annual Conference of the Society for General Microbiology in Birmingham. In an abstract for the conference, the team cautioned oxgall was no cure-all.

 “Antibacterial activity of a substance in laboratory trials does not necessarily mean the historical remedy it was taken from actually worked in toto,” they wrote.

Lee said researchers hope to turn to other remedies in Bald’s Leechbook — including purported cures for headaches and ulcers — to see what other wisdom the ancients have to offer.

“At a time when you don’t have microscope, medicine would have included things we find rather odd,” she said. “In 200 years, people will judge us.”

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Cleaning Up Old Satellites And Space Junk Could Soon Be Done With Giant Fishing Nets

March 28, 2015 / / 0 Comments

Excerpt from techtimes.com Spacecraft are all shiny and new when they leave Earth but being up in space can do a number on them, resulting into bits and pieces of junk flying around. The European Space Agency's Clean Space initiative is looking to l...

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Biologists fear DNA editing procedure can alter human DNA

March 20, 2015 / / 0 Comments




Excerpt from themarketbusiness.com

A group of biologists was alarmed with the use a new genome-editing technique to modify human DNA in a way that it can become hereditary.
The biologists worry that the new technique is so effective and easy to use that some physicians may push ahead with it before its safety can be weigh up. They also want the public to understand the ethical issues surrounding the technique, which could be used to cure genetic diseases, but also to enhance qualities like beauty or intelligence. The latter is a path that many ethicists believe should never be taken.

“You could exert control over human heredity with this technique, and that is why we are raising the issue,” said David Baltimore, a former president of the California Institute of Technology and a member of the group whose paper on the topic was published in the journal Science.

Ethicists have been concerned for decades about the dangers of altering the human germ line — meaning to make changes to human sperm, eggs or embryos that will last through the life of the individual and be passed on to future generations. Until now, these worries have been theoretical. But a technique invented in 2012 makes it possible to edit the genome precisely and with much greater ease. The technique has already been used to edit the genomes of mice, rats and monkeys, and few doubt that it would work the same way in people.

The new genome-editing technique holds the power to repair or enhance any human gene. “It raises the most fundamental of issues about how we are going to view our humanity in the future and whether we are going to take the dramatic step of modifying our own germline and in a sense take control of our genetic destiny, which raises enormous peril for humanity,” said George Daley, a stem cell expert at Boston Children’s Hospital and a member of the group.

The biologists writing in Science support continuing laboratory research with the technique, and few if any scientists believe it is ready for clinical use. Any such use is tightly regulated in the United States and Europe. American scientists, for instance, would have to present a plan to treat genetic diseases in the human germline to the Food and Drug Administration.

The paper’s authors, however, are concerned about countries that have less regulation in science. They urge that “scientists should avoid even attempting, in lax jurisdictions, germ line genome modification for clinical application in humans” until the full implications “are discussed among scientific and governmental organizations.”

Though such a moratorium would not be legally enforceable and might seem unlikely to exert global sway, there is a precedent. In 1975, scientists worldwide were asked to refrain from using a method for manipulating genes, the recombinant DNA technique, until rules had been established.

“We asked at that time that nobody do certain experiments, and in fact nobody did, to my knowledge,” said Baltimore, who was a member of the 1975 group. “So there is a moral authority you can assert from the U.S., and that is what we hope to do.”

Recombinant DNA was the first in a series of ever-improving steps for manipulating genetic material. The chief problem has always been one of accuracy, of editing the DNA at precisely the intended site, since any off-target change could be lethal. Two recent methods, known as zinc fingers and TAL effectors, came close to the goal of accurate genome editing, but both are hard to use. The new genome-editing approach was invented by Jennifer Doudna of the University of California, Berkeley, and Emmanuelle Charpentier of Umea University in Sweden.

Their method, known by the acronym Crispr-Cas9, co-opts the natural immune system with which bacteria remember the DNA of the viruses that attack them so they are ready the next time those same invaders appear. Researchers can simply prime the defense system with a guide sequence of their choice and it will then destroy the matching DNA sequence in any genome presented to it. Doudna is the lead author of the Science article calling for control of the technique and organized the meeting at which the statement was developed.

Though highly efficient, the technique occasionally cuts the genome at unintended sites. The issue of how much mistargeting could be tolerated in a clinical setting is one that Doudna’s group wants to see thoroughly explored before any human genome is edited.

Scientists also say that replacing a defective gene with a normal one may seem entirely harmless but perhaps would not be.
“We worry about people making changes without the knowledge of what those changes mean in terms of the overall genome,” Baltimore said. “I personally think we are just not smart enough — and won’t be for a very long time — to feel comfortable about the consequences of changing heredity, even in a single individual.”
Many ethicists have accepted the idea of gene therapy, changes that die with the patient, but draw a clear line at altering the germline, since these will extend to future generations. The British Parliament in February approved the transfer of mitochondria, small DNA-containing organelles, to human eggs whose own mitochondria are defective. But that technique is less far-reaching because no genes are edited.

There are two broad schools of thought on modifying the human germline, said R. Alta Charo, a bioethicist at the University of Wisconsin and a member of the Doudna group. One is pragmatic and seeks to balance benefit and risk. The other “sets up inherent limits on how much humankind should alter nature,” she said. 
Some Christian doctrines oppose the idea of playing God, whereas in Judaism and Islam there is the notion “that humankind is supposed to improve the world.” She described herself as more of a pragmatist, saying, “I would try to regulate such things rather than shut a new technology down at its beginning.”

Other scientists agree with the Doudna group’s message.
“It is very clear that people will try to do gene editing in humans,” said Rudolf Jaenisch, a stem cell biologist at the Whitehead Institute in Cambridge, Massachusetts, who was not a member of the Doudna group. “This paper calls for a moratorium on any clinical application, which I believe is the right thing to do.”
Writing in Nature last week, Edward Lanphier and other scientists involved in developing the rival zinc finger technique for genome editing also called for a moratorium on human germline modification, saying that use of current technologies would be “dangerous and ethically unacceptable.”

The International Society for Stem Cell Research said Thursday that it supported the proposed moratorium.

The Doudna group calls for public discussion but is also working to develop some more formal process, such as an international meeting convened by the National Academy of Sciences, to establish guidelines for human use of the genome-editing technique.

“We need some principled agreement that we want to enhance humans in this way or we don’t,” Jaenisch said. “You have to have this discussion because people are gearing up to do this.”

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Using X-rays, scientists read 2,000 year old scrolls charred by Mount Vesuvius

January 20, 2015 / / 0 Comments


Mount Vesuvius today



By Amina Khan 
Excerpt from latimes.com

Talk about reading between the lines! Scientists wielding X-rays say they can, for the first time, read words inside the charred, rolled-up scrolls that survived the catastrophic eruption of Mt. Vesuvius nearly two millenniums ago.
Testing the scroll
Researchers Daniel Delattre, left, and Emmanuel Brun observe the scroll before X-ray phase contrast imaging begins. (J. Delattre)
The findings, described in the journal Nature Communications, give hope to researchers who have until now been unable to read these delicate scrolls without serious risk of destroying them.
The scrolls come from a library in Herculaneum, one of several Roman towns that, along with Pompeii, was destroyed when Mt. Vesuvius erupted in AD 79. This library, a small room in a large villa, held hundreds of handwritten papyrus scrolls that had been carbonized from a furnace-like blast of 608-degree-Fahrenheit gas produced by the volcano.

“This rich book collection, consisting principally of Epicurean philosophical texts, is a unique cultural treasure, as it is the only ancient library to survive together with its books,” the study authors wrote. “The texts preserved in these papyri, now mainly stored in the Officina dei Papiri in the National Library of Naples, had been unknown to scholars before the discovery of the Herculaneum library, since they had not been copied and recopied in late Antiquity, the middle ages and Renaissance.”
So researchers have tried every which way to read these rare and valuable scrolls, which could open a singular window into a lost literary past. The problem is, these scrolls are so delicate that it’s nearly impossible to unroll them without harming them. That hasn’t kept other researchers from trying, however – sometimes successfully, and sometimes not.

“Different opening techniques, all less effective, have been tried over the years until the so-called ‘Oslo method’ was applied in the 1980s on two Herculaneum scrolls now in Paris with problematic results, since the method required the rolls to be picked apart into small pieces,” the study authors wrote. (Yikes.)

Any further attempts to physically open these scrolls were called off since then, they said, “because an excessive percentage of these ancient texts was irretrievably lost by the application of such methods.”
This is where a technique like X-ray computed tomography, which could penetrate the rolled scrolls, would come in handy. The problem is, the ancient writers used ink made of carbon pulled from smoke residue. And because the papyrus had been carbonized from the blazing heat, both paper and ink are made of roughly the same stuff. Because the soot-based ink and baked paper have about the same density, until now it’s been practically impossible to tell ink and paper apart.

But a team led by Vito Mocella of the Institute for Microelectronics and Microsystems in Naples, Italy, realized they could use a different technique called X-ray phase-contrast tomography. Unlike the standard X-ray CT scans, X-ray phase-contrast tomography examines phase shifts in the X-ray light as it passes through different structures.
Using the technique, the scientists were able to make out a few words and letters from two scrolls, one of them still rolled.

Reading these scrolls is difficult; computer reconstructions of the rolled scroll reveal that the blast of volcanic material so damaged its once-perfect whorls that its cross section looks like a half-melted tree-ring pattern. The paper inside has been thoroughly warped, and some of the letters on the paper probably distorted almost beyond recognition.
Nonetheless, the researchers were able to read a number of words and letters, which were about 2 to 3 millimeters in size. On an unrolled fragment of a scroll called “PHerc.Paris. 1,” they were able to make up the words for “would fall” and “would say.” In the twisted, distorted layers of the rolled-up papyrus called “PHerc.Paris. 4,” they could pick out individual letters: alpha, nu, eta, epsilon and others.

The letters in “PHerc.Paris. 4” are also written in a distinctive style with certain decorative flourishes that seemed very similar to a scroll called “PHerc. 1471,” which holds a text written by the Epicurean philosopher Philodemus. The researchers think they were written in the second quarter of the first century BC.


Ultimately, the researchers wrote, this work was a proofof concept to give other researchers a safe and reliable way to explore ancient philosophical works that were until now off-limits to them.

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Future Tech Watch ~ High-tech mirrors to beam heat from buildings into space ~ May replace air conditioning

November 28, 2014 / / 0 Comments



illustration of reflective panel on building

news.stanford.edu 

By Chris Cesare

A new ultrathin multilayered material can cool buildings without air conditioning by radiating warmth from inside the buildings into space while also reflecting sunlight to reduce incoming heat.

Stanford engineers have invented a material designed to help cool buildings. The material reflects incoming sunlight, and it sends heat from inside the structure directly into space as infrared radiation (represented by reddish rays).

Stanford engineers have invented a revolutionary coating material that can help cool buildings, even on sunny days, by radiating heat away from the buildings and sending it directly into space.

A team led by electrical engineering Professor Shanhui Fan and research associate Aaswath Raman reported this energy-saving breakthrough in the journal Nature.

The heart of the invention is an ultrathin, multilayered material that deals with light, both invisible and visible, in a new way.

Invisible light in the form of infrared radiation is one of the ways that all objects and living things throw off heat. When we stand in front of a closed oven without touching it, the heat we feel is infrared light. This invisible, heat-bearing light is what the Stanford invention shunts away from buildings and sends into space.

Of course, sunshine also warms buildings. The new material, in addition dealing with infrared light, is also a stunningly efficient mirror that reflects virtually all of the incoming sunlight that strikes it.

The result is what the Stanford team calls photonic radiative cooling – a one-two punch that offloads infrared heat from within a building while also reflecting the sunlight that would otherwise warm it up. The result is cooler buildings that require less air conditioning.

"This is very novel and an extraordinarily simple idea," said Eli Yablonovitch, a professor of engineering at the University of California, Berkeley, and a pioneer of photonics who directs the Center for Energy Efficient Electronics Science. "As a result of professor Fan's work, we can now [use radiative cooling], not only at night but counter-intuitively in the daytime as well."

The researchers say they designed the material to be cost-effective for large-scale deployment on building rooftops. Though still a young technology, they believe it could one day reduce demand for electricity. As much as 15 percent of the energy used in buildings in the United States is spent powering air conditioning systems.

In practice the researchers think the coating might be sprayed on a more solid material to make it suitable for withstanding the elements.

"This team has shown how to passively cool structures by simply radiating heat into the cold darkness of space," said Nobel Prize-winning physicist Burton Richter, professor emeritus at Stanford and former director of the research facility now called the SLAC National Accelerator Laboratory.

A warming world needs cooling technologies that don't require power, according to Raman, lead author of the Nature paper. 

"Across the developing world, photonic radiative cooling makes off-grid cooling a possibility in rural regions, in addition to meeting skyrocketing demand for air conditioning in urban areas," he said.

Using a window into space

The real breakthrough is how the Stanford material radiates heat away from buildings.

researchers Linxiao Zhu, Shanhui Fan, Aaswath Raman
Doctoral candidate Linxiao Zhu, Professor Shanhui Fan and research associate 
Aaswath Raman are members of the team that invented the breakthrough energy-saving material.
As science students know, heat can be transferred in three ways: conduction, convection and radiation. Conduction transfers heat by touch. That's why you don't touch an oven pan without wearing a mitt. Convection transfers heat by movement of fluids or air. It's the warm rush of air when the oven is opened. Radiation transfers heat in the form of infrared light that emanates outward from objects, sight unseen.
The first part of the coating's one-two punch radiates heat-bearing infrared light directly into space. The ultrathin coating was carefully constructed to send this infrared light away from buildings at the precise frequency that allows it to pass through the atmosphere without warming the air, a key feature given the dangers of global warming.

"Think about it like having a window into space," said Fan.

Aiming the mirror

But transmitting heat into space is not enough on its own.
This multilayered coating also acts as a highly efficient mirror, preventing 97 percent of sunlight from striking the building and heating it up.

"We've created something that's a radiator that also happens to be an excellent mirror," said Raman.

Together, the radiation and reflection make the photonic radiative cooler nearly 9 degrees Fahrenheit cooler than the surrounding air during the day.

From prototype to building panel

Making photonic radiative cooling practical requires solving at least two technical problems.

The first is how to conduct the heat inside the building to this exterior coating. Once it gets there, the coating can direct the heat into space, but engineers must first figure out how to efficiently deliver the building heat to the coating.

The second problem is production. Right now the Stanford team's prototype is the size of a personal pizza. Cooling buildings will require large panels. The researchers say there exist large-area fabrication facilities that can make their panels at the scales needed.

The cosmic fridge

More broadly, the team sees this project as a first step toward using the cold of space as a resource. In the same way that sunlight provides a renewable source of solar energy, the cold universe supplies a nearly unlimited expanse to dump heat.

"Every object that produces heat has to dump that heat into a heat sink," Fan said. "What we've done is to create a way that should allow us to use the coldness of the universe as a heat sink during the day."

In addition to Fan, Raman and Zhu, this paper has two additional co-authors: Marc Abou Anoma, a master's student in mechanical engineering who has graduated; and Eden Rephaeli, a doctoral student in applied physics who has graduated.

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