Excerpt from huffingtonpost.com When I was in kindergarten, a boy in my class tossed my favorite book over our elementary school fence. I remember crying profusely, not because I was sad to see it go, but because I was so furious that he was s...
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| MRSA attacks a human cell. The bacteria shown is the strain MRSA 252, a leading cause of hospital-associated infections. (Rocky Mountain Laboratories, NIAID, NIH) |
Excerpt from washingtonpost.com
The superbug, which is resistant to conventional antibiotics because of their overuse, shrugs at even the deadliest weapons modern medicine offers. The Centers for Disease Control and Prevention estimated MRSA contributed to the deaths of more than 5,000 people in the United States in 2013. It even attacked the NFL, and some say it could eventually kill more people than cancer. And presidential commissions have advised that technological progress is the only way to fight MRSA.
But researchers in the United Kingdom now report that the superbug proved vulnerable to an ancient remedy. The ingredients? Just a bit of garlic, some onion or leek, copper, wine and oxgall — a florid name for cow’s bile.
This medicine sounds yucky, but it’s definitely better than the bug it may be able to kill.
“We were absolutely blown away by just how effective the combination of ingredients was,” Freya Harrison of the University of Nottingham, who worked on the research, told the BBC.
The oxgall remedy, billed as an eye salve, was found in a manuscript written in Old English from the 10th century called “Bald’s Leechbook” — a sort of pre-Magna Carta physician’s desk reference. Garlic and copper are commonly thought to have antibiotic or antimicrobial properties, but seeing such ingredients in a home remedy at Whole Foods is a far cry from researchers killing a superbug with it.
According to Christina Lee, an associate professor in Viking studies at Nottingham, the MRSA research was the product of conversations among academics of many stripes interested in infectious disease and how people fought it before antibiotics.
“We were talking about the specter of antibiotic resistance,” she told The Washington Post in a phone interview. The medical researchers involved in the discussions said to the medievalists: “In your period, you guys must have had something.”
Not every recipe in Bald’s Leechbook is a gem. Other advice, via a translation from the Eastern Algo-Saxonist: “Against a woman’s chatter; taste at night fasting a root of radish, that day the chatter cannot harm thee.” And: “In case a man be a lunatic; take skin of a mereswine or porpoise, work it into a whip, swinge the man therewith, soon he will be well. Amen.”
Though the Leechbook may include misses, it may help doctors find a solution to a problem that only seems to be getting worse.
If the oxgall remedy proves effective against MRSA outside of the lab — which researchers caution it may not — it would be a godsend. Case studies of MRSA’s impact from the CDC’s charmingly named Morbidity and Mortality Weekly Report seem medieval.
“In July 1997, a 7-year-old black girl from urban Minnesota was admitted to a tertiary-care hospital with a temperature of 103 F.” Result: Death from pulmonary hemorrhage after five weeks of hospitalization.
“In January 1998, a 16-month-old American Indian girl from rural North Dakota was taken to a local hospital in shock and with a temperature of 105.2 F.” Result: After respiratory failure and cardiac arrest, death within two hours of hospital admission.
“In January 1999, a 13-year-old white girl from rural Minnesota was brought to a local hospital with fever, hemoptysis” — that’s coughing up blood — “and respiratory distress.” The result: Death from multiple organ failure after seven days in the hospital.
“We believe modern research into disease can benefit from past responses and knowledge, which is largely contained in non-scientific writings,” Lee told the Telegraph. “But the potential of these texts to contribute to addressing the challenges cannot be understood without the combined expertise of both the arts and science.”
Lee stressed that it was the combination of ingredients that proved effective against MRSA — which shows that people living in medieval times were not as barbaric as popularly thought. Even 1,000 years ago, when people got sick, other people tried to figure out how to help.
“We associate ‘medieval’ with dark, barbaric,” Lee said. “… It’s not. I’ve always believed in the pragmatic medieval ages.”
The research will be presented at the Annual Conference of the Society for General Microbiology in Birmingham. In an abstract for the conference, the team cautioned oxgall was no cure-all.
“Antibacterial activity of a substance in laboratory trials does not necessarily mean the historical remedy it was taken from actually worked in toto,” they wrote.
Lee said researchers hope to turn to other remedies in Bald’s Leechbook — including purported cures for headaches and ulcers — to see what other wisdom the ancients have to offer.
“At a time when you don’t have microscope, medicine would have included things we find rather odd,” she said. “In 200 years, people will judge us.”
The Lunatic Piran found abandoned Jure Stwerk at the Helm ...
Excerpt from
psmag.com
A far cry from the fierce Cold War Space Race between the U.S. and the Soviet Union, exploration in the 21st century is likely to be a much more globally collaborative project.
Today, NASA’s goal to put astronauts on Mars by the 2030s could be a similarly unifying project. And not only in the United States. A far cry from the fierce Cold War Space Race between the U.S. and the Soviet Union, exploration in the 21st century is likely to be a far more globally collaborative project.
Why has the idea of reaching Mars captured the world? A trip to Mars is a priority for many scientific reasons—some believe it’s the planet that most resembles our own, and one that could answer the age-old question of whether we’re alone in the universe—but there’s also been a long popular fascination with the planet, Stofan observed. Ever since Giovanni Virginio Schiaparelli first observed the canali on Mars in the 1800s or when H.G. Wells wrote about aliens from Mars in his 1898 science fiction novel, The War of the Worlds, the planet has loomed large in the public’s imagination.
NASA’s view is to turn over to the private sector those projects that in a sense have become routine so that it can focus its resources on getting to Mars.
This spirit of trans-border ownership and investment seems set to continue. One key part of this is the Global Exploration Roadmap, an effort between space agencies like NASA, France’s Centre National d’Etudes Spatiales, the Canadian Space Agency, and the Japan Aerospace Exploration Agency, among many others, that is intended to aid joint projects from the International Space Station to expeditions to the Moon and near-Earth asteroids—and to reach Mars. On a recent trip to India’s space agency, Stofan recounted to me, she met with many Indian engineers who were just as excited as the Americans to get scientists up there, not only to explore, but also to begin nailing down the question of whether there was ever life on the red planet.It’s also clear that the next stage of space exploration will not only be more global, but will equally involve greater private and public partnerships.
This environment feels a lot different from the secretive and adversarial Space Race days, when the U.S. and Soviet Union battled to reach the moon first. What’s changed? The Cold War is over, of course, but with it, the funding commitment may also be missing this time around. Stofan mentioned, in response to an audience question, that at the time of the Apollo missions, NASA got up to about four percent of the federal budget, while now it’s only around 0.4 percent. The dollars are still large, but perhaps increased international and private cooperation can be seen as an efficient, clever way to do more with less.
So, what does the future hold? NASA is extremely focused on how to get to Mars and back again safely, Stofan told the audience, but the fun role of science fiction, she suggested, is to start envisioning what the steps after that might be. For example, what might it be like to live on Mars? After all, science often gets its inspiration from the creative world. Just look at how similar mobile phones are to the communicators from Star Trek, she pointed out, or the fact that MIT students made a real-life version of the robotic sphere that Luke Skywalker trains with in Star Wars. “Stories are a great counterpoint to science,” she said.
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Illustrated image of Pluto
theweathernetwork.com
ByScott Sutherland Meteorologist, theweathernetwork.com
Friday, July 18, 2014, 12:24 PM - For over 75 years, tiny Pluto enjoyed its status as the most distant planet in our solar system, but in 2006, it was demoted down to a 'dwarf planet' and its title was passed on to Neptune. Now, though, the editor of Astronomy magazine is sounding the rallying cry to re-open the debate about Pluto's nature, which could potentially redefine what it means to be a planet.
In 2006, when the International Astronomical Union (IAU) set down an official definition for what a 'planet' is, they came up with three rules:
1) The object must be in orbit around the Sun,
2) The object must be massive enough to be a sphere by its own gravitational force. More specifically, its own gravity should pull it into a shape of hydrostatic equilibrium, and
3) It must have cleared the neighborhood around its orbit.
Everything in the solar system technically orbits around the Sun, of course. Something like the Moon doesn't qualify, though, even though it's massive enough to be roughly spherical and its 'neighborhood' is as clear as Earth's is, because it only goes around the Sun as a consequence of being in orbit around Earth. Same goes for the moons of the other planets. Asteroids and comets don't qualify because they're not big enough to become spherical by their own gravity. Even Ceres (which is roughly spherical) doesn't make the cut, because it's in the asteroid belt, thus its 'neighborhood' isn't clear.
Pluto suffers the same problem as Ceres. It's definitely in orbit around the Sun (or at least the common gravitational focus it shares with Charon is in orbit around the Sun). It is massive enough to be a sphere. It just isn't considered to have cleared its neighborhood. So, not a planet, at least by the IAU rules.
However, while the first two rules are pretty clear and easy to determine, third isn't. According to Prof. Abel Méndez, of the University of Puerto Rico at Arecibo, "there is no standard 'cleared' metric." It seems that due to the very existence of the Kuiper Belt, Pluto loses its status. However, exactly how cleared does the neighborhood have to be? There are millions of near-Earth asteroids flying around us, and there are even some asteroids that are locked into the same orbit as Earth ('Earth trojans'). There are even more asteroids near Mars' orbit, due to its proximity to the asteroid belt. Jupiter has an extremely large collection of asteroids in its orbit, both preceding it (the Greeks) and following behind (the Trojans).
Even discounting these cases, as it is, when you go further out into the solar system, it gets harder and harder for an object to clear its neighborhood. This is simply because it makes fewer orbits around the Sun compared to objects closer to the Sun, and thus it encounters the other objects in its orbit far less often. Consider Earth, going around the Sun once every year, with Pluto orbiting every 247 years. So, whereas Earth has made roughly 4.5 billion trips around the Sun since it formed, Pluto has only made 18 million similar trips (if it formed at roughly the same time).
As Astronomy magazine editor David Eicher said: "At the Pluto-like distance of 40 astronomical units — 40 times farther away from the Sun then we are now — Earth would not clear its orbit of asteroids, and so would Earth then not be classified as a planet?"
Also, since recent evidence has pointed to the fact that there may be two super-Earth-sized objects out beyond Pluto, both of them would be considered 'dwarf planets' as well, despite one potentially being 10 times the mass of Earth and the other being up to 100 times the mass of Earth.
So, when it comes to Pluto, what's the case for making it a planet again? Based on the facts above and Eicher's own thoughts:
1) the definition of what 'cleared the neighborhood around its orbit' is, itself, unclear
2) it seems unjustifiable that an object even larger than the Earth would not be considered a planet, simply because it orbits far out in our solar system
3) an object's intrinsic characteristics should dictate what kind of object it is, not its location.
Indeed, if you take the IAU's definition and attempt to apply it to all objects we know about, the multitude of worlds that we've discovered outside our solar system aren't technically planets, despite being large enough and even if they've cleared their orbit, because they don't orbit around the Sun.
So, perhaps it's time to revise the IAU's definition, not only to reconsider Pluto for planetary status, but also to make the definition applicable to a wider range of objects. Even if they changed the first rule to have 'a star' instead of 'the Sun' and changed the emphasis of the third rule to be that the object is large enough compared to the rest of the objects in its orbit to be capable of clearing its neighborhood (given enough time), it might be a much better set of conditions to measure everything against.
As Astronomy's editors offer up their time and efforts to host a renewed debate about Pluto, what do you think about its status? Should it be a planet again, remain as a dwarf planet, or perhaps something else? Leave your ideas in the comments below.
What we participate in is pretty much the name of the game. What do we spend our time, energy and intention on? What are we consciously and/or subconsciously empowering that’s leading to our own dis-empowerment? Where attention and thus intention goes, energy flows. Where is ours going, collectively and individually? Something to seriously consider on a continual basis in this massively manipulated energetic world.I’ve been blown away recently by the rapid rise in consciousness [...]
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5 Ways to Master the Art of Letting Go
Excerpt from huffingtonpost.comWe've all had to let go of things at some point or another. Whether it be a pet, friend, boyfriend, or simply graduating high school. We are constantly ending chapters in order to start new chapters.Though age and expe...
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