Tag: changing (page 2 of 14)

These 4 Ingredients in Most Processed Foods are Decimating Your Health

Mae Chan, Prevent DiseaseIt’s not just the high fat, salt or sugar content of processed foods that is driving obesity and diet-related illnesses — the lack of food diversity is killing our gut flora, claims one researcher. If we exclude sugar, approximately 80 percent of all calories in processed foods come from a combination of four ingredients.Drawing upon evidence from multiple studies, Professor of genetic epidemiology at King’s College London and author of&nbsp [...]

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Why I Love Mercury Retrograde And Why You Could Too!

by Ines SuljMercury has just gone retrograde again. This time in Gemini, the sign it rules.All the planets, except Sun and Moon, go in apparent backward motion from time to time, yet the Mercury retrograde seems to be the most famous one. Almost everyone knows about it, including the people who know nothing about astrology and those who don’t even believe in it.In astrology, when a planet is in retrograde, it doesn’t actually move backwards in the sky. It only a [...]

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Desperately Seeking ET: Fermi’s Paradox Turns 65 ~ Part 2

Excerpt from huffingtonpost.comIntroductionWhy is it so hard to find ET? After 50 years of searching, the SETI project has so far found nothing. In the latest development, on April 14, 2015 Penn State researchers announced that after searching through...

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Ancient Signs in the Sky: Did a Meteorite Change the Course of Christianity 2,000 Years Ago?


Detail, The Conversion of St. Paul. Paul and companions are knocked to the ground during the profound event.

Excerpt from ancient-origins.net

Did an ancient meteor have such a life-changing impact on witnesses of the day that it shaped a religion and altered the course of history? Astronomers theorize that the dramatic flash and boom that converted Paul the Apostle may have been an exploding meteor.

In the Christian Bible, it is written that a man named Saul experienced an event so extreme that it changed his views in an instant, and he became one of the most influential evangelists in early Christianity.

Saul was said to have been a vehement persecutor of the followers of Jesus and was traveling in search of disciples of Jesus for punishment. It is written in the fifth book of the New Testament, Acts of the Apostles, that Saul was on the road to Damascus, Syria, when a bright light appeared in the sky. So intense was the light that he was blinded for three days. What he heard was described as a great thunderous sound, or a divine voice. He and his companions are said to have been knocked to the ground by the force of the event. The experience was so profound that Saul changed his name to Paul, took up missionary journeys across the Mediterranean, and became instrumental in spreading Christianity.

The Conversion of Saint Paul – Paul and his companions are knocked to the ground by a resounding boom and brilliant light. Did a meteor cause this ancient event?
The Conversion of Saint Paul – Paul and his companions are knocked to the ground by a resounding boom and brilliant light. Did a meteor cause this ancient event? 


William Hartmann, co-founder of the Planetary Science Institute in the U.S. has connected Paul’s experience with similar accounts of exploding meteors, such as the well-recorded Chelyabinsk meteor which broke up over Russia in 2013, injuring over 1,500 people. The eyewitness descriptions and physical reactions to meteors or fireballs in the sky seem to parallel what is recorded about Paul.

Meteor trail over Chelyabinsk, Russia.
Meteor trail over Chelyabinsk, Russia. Wikimedia Commons


If true, then it’s possible that an act of nature may have been contributory in the spread and evolution of Christianity in its early days, and therefore shaped the course of history.

In a study published in the journal Meteoritics and Planetary Science, Hartmann cites major events like the meteors or asteroids over Chelyabinsk, Russia and Tunguska, Siberia as offering “opportunities to compare reactions of modern eyewitnesses to eyewitness accounts of possible ancient fireball events.” There are consistencies among the many accounts suggesting the biblical descriptions of Paul’s experience closely match known modern events, reports NewScientist.

In the biblical accounts, Paul was blinded for three days due to the intense light from the sky; it was “brighter than the sun, shining round me,” according to the text. This matches the Chelyabinsk meteor, as it was calculated to be shining around three times as bright as the sun. The blazing fireball made shadows move around the ground as it travelled.

Paul and his companions were said to have been knocked to the earth, and this also corresponds to the shockwave generated by the powerful Chelyabinsk meteor as it blasted out windows, knocked people off their feet, shook cars and buildings, and collapsed roofs.
The divine voice is said to have either boomed like thunder, or questioned Paul’s behavior (the exact sound is debated). Meteors create great, explosive booms and roars which can be scary or painful even for those who know what they’re experiencing.

To the ancients the incredible and unfamiliar natural celestial events were interpreted through cultural understandings of the day – which is to say, they were considered divine or damning.

The Chelyabinsk meteor gave off small amounts of radiation, enough to cause sunburn and temporary blindness in witnesses. Harmann suggests that Paul could have suffered photokeratitis, a temporary blindness from intense ultraviolet radiation, and this explains the return of his sight after healing.

Paul having his sight restored after being blinded by a celestial light that might have been a meteor.
Paul having his sight restored after being blinded by a celestial light that might have been a meteor. 


Hartmann told NewScientist, “Everything they are describing in those three accounts in the book of Acts are exactly the sequence you see with a fireball.”

IBTimes writes that the Acts of Apostles text describes three events of bright lights “from heaven” which took place around Damascus during the 30s B.C. If meteorites can be found in Syria, and accurately dated to the relevant timeframes, it might give support to the published theories.

Hartmann’s research aim is not to discredit Christianity, but to demonstrate how the interpretation of ancient events may have shaped how we exist today, spiritually and culturally.

This wouldn’t be the first meteorite in history to have potentially inspired worship or acted as an agent of change. In antiquity meteorites were seen as messages from the gods, or profound omens, and many cultures saw fallen meteorites as religious icons to be worshiped or as objects of protection. Jewelry and art has also been created from the space rocks.

Each year devout Muslims make the pilgrimage to Mecca in Saudi Arabia, circling the Kaaba, or black stone, and give a nod or a kiss to the meteorite that is said to rest inside the Grand Mosque. The worship of the Black Stone goes back to pre-Islamic shrines, when Semitic cultures used unusual stones to signify sites of reverence. According to Muslim belief, the stone originates from the time of Adam and the Islamic prophet Muhammad set the Black Stone in place after it fell from the skies.

A 1315 illustration inspired by the story of Muhammad and the Meccan clan elders lifting the Black Stone into place. Was the black stone a meteor from space?
A 1315 illustration inspired by the story of Muhammad and the Meccan clan elders lifting the Black Stone into place. Was the black stone a meteor from space?


In a more modern example, after the dramatic Chelyabinsk event over Russia in 2013, the ‘Church of the Meteorite’ was set up, and the followers hold rites on the shores of Lake Chebarkul where pieces of the space rock fell.

Some scientists regard the Conversion of Paul theory as speculation, but seem to welcome further evidence.
Bill Cooke, head of NASA's Meteoroid Environment Office told NewScientist, “It’s well recorded that extraterrestrial impacts have helped to shape the evolution of life on this planet. If it was a Chelyabinsk fireball that was responsible for Paul’s conversion, then obviously that had a great impact on the growth of Christianity.”

Indeed, “Some scholars call Paul the second founder of Christianity” says Justin Meggitt, religious historian at the University of Cambridge. Without the fireball, and without Paul’s conversion, perhaps Christianity would be different than it is today.
“Christianity probably would be very different without him,” Meggitt concludes.

Illumination from 1450 depicting Paul's conversion – the bright light and sound come from the sky. The event was said to change Paul, and may have changed history.
Illumination from 1450 depicting Paul's conversion – the bright light and sound come from the sky. The event was said to change Paul, and may have changed history. Public Domain
Featured Image: Detail, The Conversion of St. Paul. Paul and companions are knocked to the ground during the profound event.

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Tesla to unveil ‘mystery’ life changing product tonight!



Tesla's expected home battery announcement could spark energy revolution. SolarCity has already installed 300 Tesla-made batteries in California homes.


 Excerpt from CBC News 

Tesla CEO Elon Musk is set to make an announcement later tonight. There's been speculation that a large-scale battery announcement is expected, but it's not clear if that will be the case.



The man behind the electric car revolution is expected to unveil a large-scale battery capable of powering an entire house, during an announcement at Tesla Motors headquarters in Hawthorne, Calif.
While the battery will likely slash power bills for consumers, some say it's also a move toward democratizing energy systems.

Elon Musk, CEO of Tesla Motors, teased the announcement on Twitter a month ago, saying a major new Tesla product line will be unveiled at Hawthorne Design Studio at 8 p.m. local time Thursday. "Not a car," he wrote, sparking speculation that it may be a home battery.

Musk, who moved to Canada from South Africa and who briefly studied at Queen's University in Kingston, Ont., before transferring to the University of Pennsylvania, is also chairman of SolarCity, a solar power provider.

SolarCity has already run a pilot program where it installed 300 home batteries made by Tesla in California homes. Another 130 systems were being installed in early 2015, according to the company's website.

The product will be available again in late summer, the company says, as it's working on "the next phase" of the program.

Tesla is also in the midst of building its gigafactory, which has added to the speculation that the company is unveiling a home battery. Musk says that by 2020, the factory will produce more lithium-ion batteries than all the current factories producing them today. 

A home battery attaches to a home's electrical system and collects energy gathered by solar panels when the sun is out, Michael Ramsey, a Wall Street Journal automotive reporter, told CBC's The Current. That energy can then be used when the sun is no longer out.
'This is this shift away from very large centrally operated plants towards everybody owning their own little power grid or part of a small power grid in a condo building.'-— Warren Mabee, of Queen's University
"The idea is that you purchase this system and it allows you effectively to cut the cord," he says of a consumer's ability to forgo energy from the grid. The consumer's electricity bills would be significantly reduced because they would be paying for less electricity from the grid.

This innovation could move the world toward a future where power is generated where we need it and where we use it, says Warren Mabee, director of the Queen's Institute for Energy and Environmental Policy.

"This is this shift away from very large centrally operated plants towards everybody owning their own little power grid or part of a small power grid in a condo building," Mabee says.

In this system, centralized power generation becomes more of a backup than a driver, he says.

Costs remain high

However, the current systems are still very expensive, says Ramsey. The 300 home batteries installed in California cost upward of $20,000, he says.

"It would take years and years and years to cover the utility costs," he says. "It doesn't make sense unless the costs come down."

Ramsey views businesses as having the highest possible economic advantage from this development. The battery could offer businesses a surge of electricity when they have a high demand for power and cut their bills.

Mabee compares the cost of solar panels to cellphones. Smartphones were once very expensive, but each new generation has brought the cost down, he said.

Each year, solar panels become better and cheaper. Solar panels are getting close to their grid parity moment — when the cost of generating solar power is the same or cheaper than buying energy off the grid.

Another grid parity moment may be close, says Mabee. It won't be long before the cost of a solar panel and battery system will match the cost of purchasing electricity from the grid, he estimates.
"That magic grid parity moment is coming faster and faster," he said.

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This revolutionary discovery could help scientists see black holes for the first time


supermassive black hole
Artist's concept of the black hole.



Excerpt from finance.yahoo.com
Of all the bizarre quirks of nature, supermassive black holes are some of the most mysterious because they're completely invisible.
But that could soon change.
Black holes are deep wells in the fabric of space-time that eternally trap anything that dares too close, and supermassive black holes have the deepest wells of all. These hollows are generated by extremely dense objects thousands to billions of times more massive than our sun.
Not even light can escape black holes, which means they're invisible to any of the instruments astrophysicists currently use. Although they don't emit light, black holes will, under the right conditions, emit large amounts of gravitational waves — ripples in spacetime that propagate through the universe like ripples across a pond's surface.
And although no one has ever detected a gravitational wave, there are a handful of instruments around the world waiting to catch one.

Game-changing gravitational waves



.
black hole
This illustration shows two spiral galaxies - each with supermassive black holes at their center - as they are about to collide. 

Albert Einstein first predicted the existence of gravitational waves in 1916. According to his theory of general relativity, black holes will emit these waves when they accelerate to high speeds, which happens when two black holes encounter one another in the universe.  

As two galaxies collide, for example, the supermassive black holes at their centers will also collide. But first, they enter into a deadly cosmic dance where the smaller black hole spirals into the larger black hole, moving increasingly faster as it inches toward it's inevitable doom. As it accelerates, it emits gravitational waves.
Astrophysicists are out to observe these waves generated by two merging black holes with instruments like the Laser Interferometer Gravitational-Wave Observatory.
"The detection of gravitational waves would be a game changer for astronomers in the field," Clifford Will, a distinguished profess of physics at the University of Florida who studied under famed astrophysicist Kip Thorne told Business Insider. "We would be able to test aspects of general relativity that have not been tested."
Because these waves have never been detected, astrophysicists are still trying to figure out how to find them. To do this, they build computer simulations to predict what kinds of gravitational waves a black hole merger will produce. 

Learn by listening

In the simulation below, made by Steve Drasco at California Polytechnic State University (also known as Cal Poly), a black hole gets consumed by a supermassive black hole about 30,000 times as heavy.
You'll want to turn up the volume.
What you're seeing and hearing are two different things.
The black lines you're seeing are the orbits of the tiny black hole traced out as it falls into the supermassive black hole. What you're hearing are gravitational waves.
"The motion makes gravitational waves, and you are hearing the waves," Drasco wrote in a blog post describing his work.
Of course, there is no real sound in space, so if you somehow managed to encounter this rare cataclysmic event, you would not likely hear anything. However, what Drasco has done will help astrophysicists track down these illusive waves.

Just a little fine tuning 

Gravitational waves are similar to radio waves in that both have specific frequencies. On the radio, for example, the number corresponding to the station you're listening to represents the frequency at which that station transmits.


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gwaves
3D visualization of gravitational waves produced by 2 orbiting black holes. Right now, astrophysicists only have an idea of what frequencies two merging black holes transmit because they’re rare and hard to find. In fact, the first ever detection of an event of this kind was only announced this month. 

Therefore, astrophysicists are basically toying with their instruments like you sometimes toy with your radio to find the right station, except they don’t know what station will give them the signal they’re looking for.
What Drasco has done in his simulation is estimate the frequency at which an event like this would produce and then see how that frequency changes, so astrophysicists have a better idea of how to fine tune their instruments to search for these waves.
Detecting gravitational waves would revolutionize the field of astronomy because it would give observers an entirely new way to see the universe. Armed with this new tool, they will be able to test general relativity in ways never before made possible.

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Here’s How To Avoid One Of The Most Common Life Regrets

Excerpt from huffingtonpost.comKarl Pillemer, a Ph.D. gerontologist at Cornell University, has spent the last several years interviewing hundreds of older Americans to systematically collect their practical wisdom.His first book, 30 Lessons for Livin...

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Chicxulub Dinosaur-Killer Asteroid Impact To Be Probed For Answers To Extinction Mysteries

Excerpt from techtimes.comScientists are seeking a core sample from the Chicxulub crater that marks the remains of an asteroid impact which ended the age of the dinosaurs nearly 66 million years ago.That geological feature will be probed by scientist...

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Tombs Filled with Dozens of Mummies Discovered in Peru

A burial of a young woman found in the middle of a tomb. Analysis of her skeletal remains reveal that she suffered dental problems, including tooth loss. At one point in her life she suffered an internal hemorrhage in the meninges of her cranium. ...

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Did natural selection make the Dutch the tallest people on the planet?

Dutch national women's field hockey team



Excerpt from news.sciencemag.org
ByMartin Enserink

AMSTERDAM—Insecure about your height? You may want to avoid this tiny country by the North Sea, whose population has gained an impressive 20 centimeters in the past 150 years and is now officially the tallest on the planet. Scientists chalk up most of that increase to rising wealth, a rich diet, and good health care, but a new study suggests something else is going on as well: The Dutch growth spurt may be an example of human evolution in action.
The study, published online today in the Proceedings of the Royal Society B, shows that tall Dutch men on average have more children than their shorter counterparts, and that more of their children survive. That suggests genes that help make people tall are becoming more frequent among the Dutch, says behavioral biologist and lead author Gert Stulp of the London School of Hygiene & Tropical Medicine.

"This study drives home the message that the human population is still subject to natural selection," says Stephen Stearns, an evolutionary biologist at Yale University who wasn't involved in the study. "It strikes at the core of our understanding of human nature, and how malleable it is." It also confirms what Stearns knows from personal experience about the population in the northern Netherlands, where the study took place: "Boy, they are tall."

For many years, the U.S. population was the tallest in the world. In the 18th century, American men were 5 to 8 centimeters taller than those in the Netherlands. Today, Americans are the fattest, but they lost the race for height to northern Europeans—including Danes, Norwegians, Swedes, and Estonians—sometime in the 20th century.

Just how these peoples became so tall isn't clear, however. Genetics has an important effect on body height: Scientists have found at least 180 genes that influence how tall you become. Each one has only a small effect, but together, they may explain up to 80% of the variation in height within a population. Yet environmental factors play a huge role as well. The children of Japanese immigrants to Hawaii, for instance, grew much taller than their parents. Scientists assume that a diet rich in milk and meat played a major role.

The Dutch have become so much taller in such a short period that scientists chalk most of it up to their changing environment. As the Netherlands developed, it became one of the world's largest producers and consumers of cheese and milk. An increasingly egalitarian distribution of wealth and universal access to health care may also have helped.

Still, scientists wonder whether natural selection has played a role as well. For men, being tall is associated with better health, attractiveness to the opposite sex, a better education, and higher income—all of which could lead to more reproductive success, Stulp says.
Yet studies in the United States don't show this. Stulp's own research among Wisconsinites born between 1937 and 1940, for instance, showed that average-sized men had more children than shorter and taller men, and shorter women had more children than those of average height. Taken together, Stulp says, this suggests natural selection in the United States pulls in the opposite direction of environmental factors like diet, making people shorter instead of taller. That may explain why the growth in average American height has leveled off.

Stulp—who says his towering 2-meter frame did not influence his research interest—wondered if the same was true in his native country. To find out, he and his colleagues turned to a database tracking key life data for almost 100,000 people in the country's three northern provinces. The researchers included only people over 45 who were born in the Netherlands to Dutch-born parents. This way, they had a relatively accurate number of total children per subject (most people stop having children after 45) and they also avoided the effects of immigration.

In the remaining sample of 42,616 people, taller men had more children on average, despite the fact that they had their first child at a higher age. The effect was small—an extra 0.24 children at most for taller men—but highly significant. (Taller men also had a smaller chance of remaining childless, and a higher chance of having a partner.)  The same effect wasn't seen in women, who had the highest reproductive success when they were of average height.  The study suggests this may be because taller women had a smaller chance of finding a mate, while shorter women were at higher risk of losing a child.

Because tall men are likely to pass on the genes that made them tall, the outcome suggests that—in contrast to Americans—the Dutch population is evolving to become taller, Stulp says. "This is not what we've seen in other studies—that's what makes it exciting," says evolutionary biologist Simon Verhulst of the University of Groningen in the Netherlands, who was Stulp's Ph.D. adviser but wasn't involved in the current study. Verhulst points out that the team can't be certain that genes involved in height are actually becoming more frequent, however, as the authors acknowledge.

The study suggests that sexual selection is at work in the Dutch population, Stearns says: Dutch women may prefer taller men because they expect them to have more resources to invest in their children. But there are also other possibilities. It could be that taller men are more resistant to disease, Stearns says, or that they are more likely to divorce and start a second family. "It will be a difficult question to answer.”

Another question is why tall men in Holland are at a reproductive advantage but those in the United States are not. Stulp says he can only speculate. One reason may be that humans often choose a partner who's not much shorter or taller than they are themselves. Because shorter women in the United States have more children, tall men may do worse than those of average height because they're less likely to partner with a short woman.

In the end, Stearns says, the advantage of tall Dutchmen may be only temporary. Often in evolution, natural selection will favor one trend for a number of generations, followed by a stabilization or even a return to the opposite trend. In the United States, selection for height appears to have occurred several centuries ago, leading to taller men, and then it stopped. "Perhaps the Dutch caught up and actually overshot the American men," he says.

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Scientists Take Key Step to Resurrecting Extinct Woolly Mammoth; First Mammoth Could be Born in 2018

Excerpt from en.yibada.comScientists from Harvard University announced their success in splicing DNA from the extinct woolly mammoth into living cells of an Asian elephant, making it possible to "de-extinct" the animal that died-off 4,000 years ago....

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How Quantum Physics will change your life and amaze the world!

 Excerpt from educatinghumanity.com "Anyone not shocked by quantum mechanics has not yet understood it."Niels Bohr10 Ways Quantum Physics Will Change the WorldEver want to have a "life do over", teleport, time travel, have your computer wor...

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Biologists fear DNA editing procedure can alter human DNA




Excerpt from themarketbusiness.com

A group of biologists was alarmed with the use a new genome-editing technique to modify human DNA in a way that it can become hereditary.
The biologists worry that the new technique is so effective and easy to use that some physicians may push ahead with it before its safety can be weigh up. They also want the public to understand the ethical issues surrounding the technique, which could be used to cure genetic diseases, but also to enhance qualities like beauty or intelligence. The latter is a path that many ethicists believe should never be taken.


“You could exert control over human heredity with this technique, and that is why we are raising the issue,” said David Baltimore, a former president of the California Institute of Technology and a member of the group whose paper on the topic was published in the journal Science.

Ethicists have been concerned for decades about the dangers of altering the human germ line — meaning to make changes to human sperm, eggs or embryos that will last through the life of the individual and be passed on to future generations. Until now, these worries have been theoretical. But a technique invented in 2012 makes it possible to edit the genome precisely and with much greater ease. The technique has already been used to edit the genomes of mice, rats and monkeys, and few doubt that it would work the same way in people.

The new genome-editing technique holds the power to repair or enhance any human gene. “It raises the most fundamental of issues about how we are going to view our humanity in the future and whether we are going to take the dramatic step of modifying our own germline and in a sense take control of our genetic destiny, which raises enormous peril for humanity,” said George Daley, a stem cell expert at Boston Children’s Hospital and a member of the group.

The biologists writing in Science support continuing laboratory research with the technique, and few if any scientists believe it is ready for clinical use. Any such use is tightly regulated in the United States and Europe. American scientists, for instance, would have to present a plan to treat genetic diseases in the human germline to the Food and Drug Administration.

The paper’s authors, however, are concerned about countries that have less regulation in science. They urge that “scientists should avoid even attempting, in lax jurisdictions, germ line genome modification for clinical application in humans” until the full implications “are discussed among scientific and governmental organizations.”

Though such a moratorium would not be legally enforceable and might seem unlikely to exert global sway, there is a precedent. In 1975, scientists worldwide were asked to refrain from using a method for manipulating genes, the recombinant DNA technique, until rules had been established.

“We asked at that time that nobody do certain experiments, and in fact nobody did, to my knowledge,” said Baltimore, who was a member of the 1975 group. “So there is a moral authority you can assert from the U.S., and that is what we hope to do.”

Recombinant DNA was the first in a series of ever-improving steps for manipulating genetic material. The chief problem has always been one of accuracy, of editing the DNA at precisely the intended site, since any off-target change could be lethal. Two recent methods, known as zinc fingers and TAL effectors, came close to the goal of accurate genome editing, but both are hard to use. The new genome-editing approach was invented by Jennifer Doudna of the University of California, Berkeley, and Emmanuelle Charpentier of Umea University in Sweden.

Their method, known by the acronym Crispr-Cas9, co-opts the natural immune system with which bacteria remember the DNA of the viruses that attack them so they are ready the next time those same invaders appear. Researchers can simply prime the defense system with a guide sequence of their choice and it will then destroy the matching DNA sequence in any genome presented to it. Doudna is the lead author of the Science article calling for control of the technique and organized the meeting at which the statement was developed.

Though highly efficient, the technique occasionally cuts the genome at unintended sites. The issue of how much mistargeting could be tolerated in a clinical setting is one that Doudna’s group wants to see thoroughly explored before any human genome is edited.

Scientists also say that replacing a defective gene with a normal one may seem entirely harmless but perhaps would not be.
“We worry about people making changes without the knowledge of what those changes mean in terms of the overall genome,” Baltimore said. “I personally think we are just not smart enough — and won’t be for a very long time — to feel comfortable about the consequences of changing heredity, even in a single individual.”
Many ethicists have accepted the idea of gene therapy, changes that die with the patient, but draw a clear line at altering the germline, since these will extend to future generations. The British Parliament in February approved the transfer of mitochondria, small DNA-containing organelles, to human eggs whose own mitochondria are defective. But that technique is less far-reaching because no genes are edited.

There are two broad schools of thought on modifying the human germline, said R. Alta Charo, a bioethicist at the University of Wisconsin and a member of the Doudna group. One is pragmatic and seeks to balance benefit and risk. The other “sets up inherent limits on how much humankind should alter nature,” she said. 
Some Christian doctrines oppose the idea of playing God, whereas in Judaism and Islam there is the notion “that humankind is supposed to improve the world.” She described herself as more of a pragmatist, saying, “I would try to regulate such things rather than shut a new technology down at its beginning.”

Other scientists agree with the Doudna group’s message.
“It is very clear that people will try to do gene editing in humans,” said Rudolf Jaenisch, a stem cell biologist at the Whitehead Institute in Cambridge, Massachusetts, who was not a member of the Doudna group. “This paper calls for a moratorium on any clinical application, which I believe is the right thing to do.”
Writing in Nature last week, Edward Lanphier and other scientists involved in developing the rival zinc finger technique for genome editing also called for a moratorium on human germline modification, saying that use of current technologies would be “dangerous and ethically unacceptable.”

The International Society for Stem Cell Research said Thursday that it supported the proposed moratorium.

The Doudna group calls for public discussion but is also working to develop some more formal process, such as an international meeting convened by the National Academy of Sciences, to establish guidelines for human use of the genome-editing technique.

“We need some principled agreement that we want to enhance humans in this way or we don’t,” Jaenisch said. “You have to have this discussion because people are gearing up to do this.”

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