Tag: biology (page 1 of 5)

Dept. of Defense Agency DARPA Confirms Thought to Computer Technology Research

January 22, 2016 / / 0 Comments

New effort aims for fully implantable devices able to connect with up to one million neurons

(Note from Greg: Implantable devices does not in any way imply mechanical or physical implants are necessary. Ex-CIA scientist Dr. Robert Duncan states in his book Project: Soul Catcher, wireless implantable brain to computer technology already exists and is in use.)  


From DARPA's official website
outreach@darpa.mil
1/19/2016

A new DARPA program aims to develop an implantable neural interface able to provide unprecedented signal resolution and data-transfer bandwidth between the human brain and the digital world. The interface would serve as a translator, converting between the electrochemical language used by neurons in the brain and the ones and zeros that constitute the language of information technology. The goal is to achieve this communications link in a biocompatible device no larger than one cubic centimeter in size, roughly the volume of two nickels stacked back to back.

The program, Neural Engineering System Design (NESD), stands to dramatically enhance research capabilities in neurotechnology and provide a foundation for new therapies.

“Today’s best brain-computer interface systems are like two supercomputers trying to talk to each other using an old 300-baud modem,” said Phillip Alvelda, the NESD program manager. “Imagine what will become possible when we upgrade our tools to really open the channel between the human brain and modern electronics.”

Among the program’s potential applications are devices that could compensate for deficits in sight or hearing by feeding digital auditory or visual information into the brain at a resolution and experiential quality far higher than is possible with current technology.

Neural interfaces currently approved for human use squeeze a tremendous amount of information through just 100 channels, with each channel aggregating signals from tens of thousands of neurons at a time. The result is noisy and imprecise. In contrast, the NESD program aims to develop systems that can communicate clearly and individually with any of up to one million neurons in a given region of the brain.

Achieving the program’s ambitious goals and ensuring that the envisioned devices will have the potential to be practical outside of a research setting will require integrated breakthroughs across numerous disciplines including neuroscience, synthetic biology, low-power electronics, photonics, medical device packaging and manufacturing, systems engineering, and clinical testing. In addition to the program’s hardware challenges, NESD researchers will be required to develop advanced mathematical and neuro-computation techniques to first transcode high-definition sensory information between electronic and cortical neuron representations and then compress and represent those data with minimal loss of fidelity and functionality.

To accelerate that integrative process, the NESD program aims to recruit a diverse roster of leading industry stakeholders willing to offer state-of-the-art prototyping and manufacturing services and intellectual property to NESD researchers on a pre-competitive basis. In later phases of the program, these partners could help transition the resulting technologies into research and commercial application spaces.

To familiarize potential participants with the technical objectives of NESD, DARPA will host a Proposers Day meeting that runs Tuesday and Wednesday, February 2-3, 2016, in Arlington, Va. The Special Notice announcing the Proposers Day meeting is available at https://www.fbo.gov/spg/ODA/DARPA/CMO/DARPA-SN-16-16/listing.html. More details about the Industry Group that will support NESD is available at https://www.fbo.gov/spg/ODA/DARPA/CMO/DARPA-SN-16-17/listing.html. A Broad Agency Announcement describing the specific capabilities sought is available at: http://go.usa.gov/cP474.
DARPA anticipates investing up to $60 million in the NESD program over four years.

NESD is part of a broader portfolio of programs within DARPA that support President Obama’s brain initiative. For more information about DARPA’s work in that domain, please visit: http://www.darpa.mil/program/our-research/darpa-and-the-brain-initiative.

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Antidepressants May be Worsening Depression, Not Treating It

July 6, 2015 / / 0 Comments

Julie Fidler, Natural SocietyCould it all be based on a myth?For years we’ve been told that depression is caused by low serotonin levels in the brain.Now, a leading professor of psychiatry is warning that belief is little more than a dangerous miscommunication, saying the marketing of selective serotonin reuptake inhibitor (SSRI) drugs is “based on a myth.”SSRI use began to skyrocket in the early 1990’s. The drugs were seen as a safer alternative to [...]

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Think the Anti-GMO Movement is Unscientific? Think Again

May 26, 2015 / / 0 Comments

Sayer Ji, Green Med Info“Anyone that says, ‘Oh, we know that this is perfectly safe,’ I say is either unbelievably stupid, or deliberately lying. The reality is, we don’t know. The experiments simply haven’t been done, and now we have become the guinea pigs.”  ~ David Suzuki, geneticistNow that the mainstream media is catching on to the public sentiment against GMO food, or at least against unlabeled GMO food, to the tune o [...]

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11 Common Symptoms of the Global Depopulation Slow Kill

May 13, 2015 / / 0 Comments

Sigmund Fraud, Staff Writer“Maintain humanity under 500,000,000 in perpetual balance with nature.” – The Georgia GuidestonesThe full-spectrum global attack on human health is quite obvious to see for anyone who is paying attention and in search of wellness. So many of the factors that are negatively influencing public heath could easily be prevented or removed from society, yet the decisions of the ruling class continue to ensure that our food supply [...]

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US Government Admits Americans Have Been Overdosed on Fluoride

May 12, 2015 / / 0 Comments

Dr. MercolaThe US government has finally admitted they’ve overdosed Americans on fluoride and, for first time since 1962, are lowering its recommended level of fluoride in drinking water.1,2,3About 40 percent of American teens have dental fluorosis,4 a condition referring to changes in the appearance of tooth enamel—from chalky-looking lines and splotches to dark staining and pitting—caused by long-term ingestion of fluoride during the time teeth are forming.In some areas, fluoro [...]

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Desperately Seeking Extraterrestrials ~ Fermi’s Paradox Turns 65 ~ Part 1

May 4, 2015 / / 0 Comments

Excerpt from huffingtonpost.comIntroduction 65 years ago, in 1950, while having lunch with colleagues Edward Teller and Herbert York, Nobel physicist Enrico Fermi suddenly blurted out, "Where is everybody?" His question is now known as Fermi's p...

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Lab for genetic modification of human embryos just $2,000 away – report

May 1, 2015 / / 0 Comments


Reuters / Christian Charisius



Reuters

With the right expertise in molecular biology, one could start a basic laboratory to modify human embryos using a genome-editing computer technique all for a couple thousand dollars, according to a new report.

Genetic modification has received heightened scrutiny recently following last week’s announcement that Chinese researchers had, for the first time, successfully edited human embryos’ genomes. 
The team at Sun Yat-Sen University in Guangzhou, China, used CRISPR (clustered regularly interspaced palindromic repeats), a technique that relies on “cellular machinery” used by bacteria in defense against viruses. 

This machinery is copied and altered to create specific gene-editing complexes, which include the wonder enzyme Cas9. The enzyme works its way into the DNA and can be used to alter the molecule from the inside. The combination is attached to an RNA guide that takes the gene-editing complex to its target, telling Cas9 where to operate. 

Use of the CRISPR technique is not necessarily relegated to the likes of cash-flush university research operations, according to a report by Business Insider. 


Geneticist George Church, who runs a top CRISPR research program at the Harvard Medical School, said the technique could be employed with expert knowledge and about half of the money needed to pay for an average annual federal healthcare plan in 2014 -- not to mention access to human embryos. 

"You could conceivably set up a CRISPR lab for $2,000,” he said, according to Business Insider. 

Other top researchers have echoed this sentiment. 

"Any scientist with molecular biology skills and knowledge of how to work with [embryos] is going to be able to do this,” Jennifer Doudna, a biologist at the University of California, Berkeley, recently told MIT Tech Review, which reported that Doudna co-discovered how to edit genetic code using CRISPR in 2012. 

Last week, the Sun Yat-Sen University research team said it attempted to cure a gene defect that causes beta-thalassemia (a genetic blood disorder that could lead to severe anemia, poor growth, skeletal abnormalities and even death) by editing the germ line. For that purpose they used a gene-editing technique based on injecting non-viable embryos with a complex, which consists of a protective DNA element obtained from bacteria and a specific protein. 

"I suspect this week will go down as a pivotal moment in the history of medicine," wrote science journalist Carl Zimmer for National Geographic.


Response to the new research has been mixed. Some experts say the gene editing could help defeat genetic diseases even before birth. Others expressed concern. 

“At present, the potential safety and efficacy issues arising from the use of this technology must be thoroughly investigated and understood before any attempts at human engineering are sanctioned, if ever, for clinical testing,” a group of scientists, including some who had worked to develop CRISPR, warned in Science magazine. 

Meanwhile, the director of the US National Institutes for Health (NIH) said the agency would not fund such editing of human embryo genes. 

“Research using genomic editing technologies can and are being funded by NIH,” Francis Collins said Wednesday. “However, NIH will not fund any use of gene-editing technologies in human embryos. The concept of altering the human germline in embryos for clinical purposes ... has been viewed almost universally as a line that should not be crossed.”

Although the discovery of CRISPR sequences dates back to 1987 – when it was first used to cure bacteria of viruses – its successes in higher animals and humans were only achieved in 2012-13, when scientists achieved a revolution by combining the resulting treatment system with Cas9 for the first time. 


On April 17, the MIT’s Broad Institute announced that has been awarded the first-ever patent for working with the Crisp-Cas9 system. 

The institute’s director, Eric Lander, sees the combination as “an extraordinary, powerful tool. The ability to edit a genome makes it possible to discover the biological mechanisms underlying human biology.”

The system’s advantage over other methods is in that it can also target several genes at the same time, working its way through tens of thousands of so-called 'guide' RNA sequences that lead them to the weapon to its DNA targets. 

Meanwhile, last month in the UK, a healthy baby was born from an embryo screened for genetic diseases, using karyomapping, a breakthrough testing method that allows doctors to identify about 60 debilitating hereditary disorders.

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Guiding Our Search for Life on Other Earths

April 13, 2015 / / 0 Comments


The James Webb Telescope


Excerpt from space.com

 A telescope will soon allow astronomers to probe the atmosphere of Earthlike exoplanets for signs of life. To prepare, astronomer Lisa Kaltenegger and her team are modeling the atmospheric fingerprints for hundreds of potential alien worlds. Here's how:
The James Webb Space Telescope, set to launch in 2018, will usher a new era in our search for life beyond Earth. With its 6.5-meter mirror, the long-awaited successor to Hubble will be large enough to detect potential biosignatures in the atmosphere of Earthlike planets orbiting nearby stars.
And we may soon find a treasure-trove of such worlds. The forthcoming exoplanet hunter TESS (Transiting Exoplanet Survey Satellite), set to launch in 2017, will scout the entire sky for planetary systems close to ours. (The current Kepler mission focuses on more distant stars, between 600 and 3,000 light-years from Earth.) 

Astronomer Lisa Kaltenegger




While TESS will allow for the brief detection of new planets, the larger James Webb will follow up on select candidates and provide clues about their atmospheric composition. But the work will be difficult and require a lot of telescope time.
"We're expecting to find thousands of new planets with TESS, so we'll need to select our best targets for follow-up study with the Webb telescope," says Lisa Kaltenegger, an astronomer at Cornell University and co-investigator on the TESS team.
To prepare, Kaltenegger and her team at Cornell's Institute for Pale Blue Dots are building a database of atmospheric fingerprints for hundreds of potential alien worlds. The models will then be used as "ID cards" to guide the study of exoplanet atmospheres with the Webb and other future large telescopes.
Kaltenegger described her approach in a talk for the NASA Astrobiology Institute's Director Seminar Series last December.
"For the first time in human history, we have the technology to find and characterize other worlds," she says. "And there's a lot to learn."

Detecting life from space  

In its 1990 flyby of Earth, the Galileo spacecraft took a spectrum of sunlight filtered through our planet's atmosphere. In a 1993 paper in the journal Nature, astronomer Carl Sagan analyzed that data and found a large amount of oxygen together with methane — a telltale sign of life on Earth. These observations established a control experiment for the search of extraterrestrial life by modern spacecraft.
"The spectrum of a planet is like a chemical fingerprint," Kaltenegger says. "This gives us the key to explore alien worlds light years away."
Current telescopes have picked up the spectra of giant, Jupiter-like exoplanets. But the telescopes are not large enough to do so for smaller, Earth-like worlds. The James Webb telescope will be our first shot at studying the atmospheres of these potentially habitable worlds.
Some forthcoming ground-based telescopes — including the Giant Magellan Telescope (GMT), planned for completion in 2020, and the European Extremely Large Telescope (E-ELT), scheduled for first light in 2024 — may also be able to contribute to that task. [The Largest Telescopes on Earth: How They Compare]
And with the expected discovery by TESS of thousands of nearby exoplanets, the James Webb and other large telescopes will have plenty of potential targets to study. Another forthcoming planet hunter, the Planetary Transits and Oscillations of stars (PLATO), a planned European Space Agency mission scheduled for launch around 2022-2024, will contribute even more candidates.
However, observation time for follow-up studies will be costly and limited.
"It will take hundreds of hours of observation to see atmospheric signatures with the Webb telescope," Kaltenegger says. "So we'll have to pick our targets carefully."

Giant Magellan Telescope
Set to see its first light in 2021, The Giant Magellan Telescope will be the world’s largest telescope.

Getting a head start

To guide that process, Kaltenegger and her team are putting together a database of atmospheric fingerprints of potential alien worlds. "The models are tools that can teach us how to observe and help us prioritize targets," she says.
To start, they have modeled the chemical fingerprint of Earth over geological time. Our planet's atmosphere has evolved over time, with different life forms producing and consuming various gases. These models may give astronomers some insight into a planet's evolutionary stage.
Other models take into consideration the effects of a host of factors on the chemical signatures — including water, clouds, atmospheric thickness, geological cycles, brightness of the parent star, and even the presence of different extremophiles.
"It's important to do this wide range of modeling right now," Kaltenegger said, "so we're not too startled if we detect something unexpected. A wide parameter space can allow us to figure out if we might have a combination of these environments."
She added: "It can also help us refine our modeling as fast as possible, and decide if more measurements are needed while the telescope is still in space. It's basically a stepping-stone, so we don't have to wait until we get our first measurements to understand what we are seeing. Still, we'll likely find things we never thought about in the first place."
 

A new research center

The spectral database is one of the main projects undertaken at the Institute for Pale Blue Dots, a new interdisciplinary research center founded in 2014 by Kaltenegger. The official inauguration will be held on May 9, 2015.
"The crux of the institute is the characterization of rocky, Earth-like planets in the habitable zone of nearby stars," Kaltenergger said. "It's a very interdisciplinary effort with people from astronomy, geology, atmospheric modeling, and hopefully biology."
She added: "One of the goal is to better understand what makes a planet a life-friendly habitat, and how we can detect that from light years away. We're on the verge of discovering other pale blue dots. And with Sagan's legacy, Cornell University is a really great home for an institute like that."

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UV light reveals hidden colors in ancient shells

April 3, 2015 / / 0 Comments



UV light revealed the way ancient shells looked millions of years ago.


Excerpt from perfscience.com


Using ultra-violet (UV) light, scientists have revealed astonishing colors of about 30 ancient seashells. According to PLOS, the seashells, which are estimated to be between 6.6 and 4.8 million years old, were looking white in regular white light. The true colors of the shells appeared in UV light.




According to the researchers, “The biology of modern Conidae (cone snails)-which includes the hyperdiverse genus Conus-has been intensively studied, but the fossil record of the clade remains poorly understood, particularly within an evolutionary framework”.

In the presence of UV light, the organic matter remaining in the shells fluoresces. With this, the shells appeared similar to what they looked when living creatures used to live in them. It is yet unclear which particular compounds in the shells are releasing the light when exposed to UV rays. With the help of the technique, the researchers were able to document the coloration patterns of 28 different cone shell species found in the Dominican Republic. Out of these 28 shells, 13 were found to be the species, which were not known earlier. And this could help know about the relationship between modern species.

San Jose State University geologist Jonathan Hendricks exposed over 350 fossil specimens to ultraviolet light. 

The coloration patterns of the ancient species were compared with existing animals and doing this, researchers found many displayed similarities. According to this finding, some modern species emerge from lineages. These lineages began in the Caribbean millions of years ago.

The newly distinguished species, Conus carlottae, was also among the newly distinguished species and it has a polka-dotted shell, which is not found in modern cone snails today. Researchers are now using UV light to emit color from porcelain white seashell fossils.

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Have Aliens Left The Universe? Theory Predicts We’ll Follow

March 13, 2015 / / 0 Comments

























Excerpt from robertlanza.com

In Star Wars, the bars are bustling with all types of alien creatures. And then, of course, there’s Yoda and Chewbacca. Recently, renowned scientist Stephen Hawking stated that he too believes aliens exist: “To my mathematical brain, the numbers alone make thinking about aliens perfectly rational.”

Hawking thinks we should be cautious about interacting with aliens — that they might raid Earth’s resources, take our ores, and then move on like pirates. “I imagine they might exist in massive ships, having used up all the resources from their home planet. Such advanced aliens would perhaps become nomads, looking to conquer and colonize whatever planets they can reach.”
But where are they all anyhow?

For years, NASA and others have been searching for extraterrestrial intelligence. The universe is 13.7 billion years old and contains some 10 billion trillion stars. Surely, in this lapse of suns, advanced life would have evolved if it were possible. Yet despite half a century of scanning the sky, astronomers have failed to find any evidence of life or to pick up any of the interstellar radio signals that our great antennas should be able to easily detect.

Some scientists point to the “Fermi Paradox,” noting that extraterrestrials should have had plenty of time to colonize the entire galaxy but that perhaps they’ve blown themselves up. It’s conceivable the problem is more fundamental and that the answer has to do with the evolutionary course of life itself.

Look at the plants in your backyard. What are they but a stem with roots and leaves bringing nutriments to the organism? After billions of years of evolution, it was inevitable life would acquire the ability to locomote, to hunt and see, to protect itself from competitors. 
Observe the ants in the woodpile — they can engage in combat just as resolutely as humans. Our guns and ICBM are merely the mandibles of a cleverer ant. The effort for self-preservation is vague and varied. But when we’ve overcome our struggles, what do we do next? Build taller and more splendid houses?

What happens after life completes its transition to perfection? Perhaps across space, more advanced intelligences have taken the next evolutionary step. Perhaps they’ve evolved beyond the three dimensions we vertebrates know. A new theory — Biocentrism — tells us that space and time aren’t physical matrices, but simply tools our mind uses to put everything together. These algorithms are the key to consciousness, and why space and time — indeed the properties of matter itself — are relative to the observer. More advanced civilizations would surely understand these algorithms well enough to create realities that we can’t even imagine, and to have expanded beyond our corporeal cage.

Like breathing, we take for granted how our mind puts everything together. I can recall a dream I had of a flying saucer landing in Times Square. It was so real it took awhile to convince myself that it was a dream (that I was actually at home in bed). I was standing in a crowd surrounded by skyscrapers when a massive spaceship appeared overhead. Everyone started running. My mind had somehow generated this spatio-temporal experience out of electrochemical information. I could feel the vibrations under my feet as the ship started to land, merging this 3D world with my inner thoughts and sensations.

Although I was in bed with my eyes closed, I was able to run and move my arms and fingers. My mind had created a fully functioning body and placed it in a virtual world (replete with clouds in the sky and the Sun) that was indistinguishable from the one I’m in right now. Life as we know it is defined by this spatial-temporal logic, which traps us in the universe of up and down. But like my dream, quantum theory confirms that the properties of particles in the “real” world are also observer-determined.

Other information systems surely exist that correspond to other physical realities, universes based on logic completely different from ours and not based on space and time as we know it. In fact, the simplest invertebrates may only experience existence in one dimension of space. Evolutionary biology suggests life has progressed from a one dimensional reality, to two dimensions to three dimensions, and there’s no scientific reason to think that the evolution of life stops there.

Advanced civilizations would certainly have changed the algorithms so that instead of being trapped in the linear dimensions we find ourselves in, their consciousness moves through the multiverse and beyond. Why would Aliens build massive ships and spend thousands of years to colonize planetary systems (most of which are probably useless and barren), when they could simply tinker with the algorithms and get whatever they want?

Life on Earth is just beginning to send its shoots upward into the heavens. We’ve even flung a piece of metal outside the solar system. Affixed to the spacecraft is a record with greetings in 60 languages. One can’t but wonder whether some civilization more advanced than ours will come upon it. Or will it just drift across the gulf of space? To me the answer is clear. But in case I’m wrong, I have a pitch fork guarding the ore in my backyard.

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Could Saturn’s moon Titan host an alternate type of life?

March 5, 2015 / / 0 Comments


Titan


Excerpt from mashable.com

In a world first, chemical engineers have taken a different look at a question astronomers and biologists have been pondering for decades: Does Saturn moon Titan host life?

Of course, Titan is way too hostile for life as we know it to eke out an existence — it is a frigid world awash with liquid methane and ethane and a noxious atmosphere devoid of any liquid water. But say if there is a different kind of biology, a life as we don't know it, thriving on the organic chemistry that is abundant on Titan's surface?

Normally, astrobiologists combine what we know about Earth's biosphere and astronomers zoom in on other stars containing exoplanets in the hope that some of those alien world have some similarities to Earth. By looking for small rocky exoplanets orbiting inside their star's habitable zones, we are basically looking for a "second Earth" where liquid water is at least possible. Where there's liquid water on Earth, there's inevitably life, so scientists seeking out alien life 'follow the water' in the hope of finding life with a similar terrestrial template on other planets.

Titan, however, does not fall into this category, it is about as un-Earth-like as you can get. So, chemical molecular dynamics expert Paulette Clancy and James Stevenson, a graduate student in chemical engineering, from Cornell University, Ithaca, New York, have looked at Titan in a different light and created a theoretical model of a methane-based, oxygen-free life form that could thrive in that environment.

There is no known template for this kind of life on Earth, but the researchers have studied what chemicals are in abundance on Titan and worked out how a very different kind of life could be sparked.

As a collaborator on the NASA/ESA Cassini-Huygens mission, Lunine, professor in the Physical Sciences in the College of Arts and Sciences’ Department of Astronomy, has been fascinated with the possibility of methane-based life existing on Titan for some time, so he joined forces with Clancy and Stevenson to see what this hypothetical life form might look like.

In their research published in the journal Science Advances on Feb. 27, Clancy and Stevenson focused on building a cell membrane "composed of small organic nitrogen compounds and capable of functioning in liquid methane temperatures of 292 degrees below zero (Fahrenheit; or 94 Kelvin)," writes a Cornell press release. On Earth, water-based molecules form phospholipid bilayer membranes that give cells structure, housing organic materials inside while remaining permeable. On Titan, liquid water isn't available to build these cell membranes.

"We're not biologists, and we're not astronomers, but we had the right tools," said Clancy, lead researcher of the study. "Perhaps it helped, because we didn't come in with any preconceptions about what should be in a membrane and what shouldn't. We just worked with the compounds that we knew were there and asked, 'If this was your palette, what can you make out of that?'"

The researchers were able to model the ideal cell that can do all the things that life can do (i.e. support metabolism and reproduction), but constructed it from nitrogen, carbon and hydrogen-based molecules that are known to exist in Titan's liquid methane seas. This chemical configuration gives this theoretical alien cell stability and flexibility in a similar manner to Earth life cells.
"The engineers named their theorized cell membrane an 'azotosome,' 'azote' being the French word for nitrogen. 'Liposome' comes from the Greek 'lipos' and 'soma' to mean 'lipid body;' by analogy, 'azotosome' means 'nitrogen body.'" — Cornell
"Ours is the first concrete blueprint of life not as we know it," said lead author Stevenson, who also said that he was inspired, in part, by Isaac Asimov, who wrote the 1962 essay "Not as We Know It" about non-water-based life.

Having identified a possible type of cell membrane chemistry that functions in the Titan environment as a cell on Earth might, the next step is to model how such a hypothetical type of biology would function on Titan. In the long run, we might also be able to model what kinds of observable indicators we should look for that might reveal that alien biology's presence.

That way, should a mission be eventually sent to Titan's seas, sampling the chemical compounds in the soup of organics may reveal a biology of a very alien nature.
Scientists have been trying to know if life could exist on Titan, the largest moon of Saturn. According to scientists, there are possibilities that life could survive amidst methane-based lakes of Titan. After conducting many studies, they have found signs of life on Titan, but the scientists also said that life will not be like life on earth.
As per some scientific reports, Titan is the only object other than earth which has clear evidence of stable bodies of surface liquid. Like earth, the moon has mountains, islands, lakes and storms, but it doesn’t have oxygen, which is a major element to support life. It means that only oxygen-free and methane-based can exist on Titan.
According to lead researcher Paulette Clancy, “We didn’t come in with any preconceptions about what should be in a membrane and what shouldn’t. We just worked with the compounds that, we knew were there and asked, ‘If this was your palette, what can you make out of that”.
Clancy said although they are not biologists or astronomers, they had the right tools to find life on Saturn’s largest moon. Adding to that, the researchers didn’t know what should be in a membrane and what should be not. They worked with compounds and found that life can exist on Titan, but would be very different from earth’s life, Clancy added.
According to reports, the researchers had used a molecular dynamics method to know about Titan. They screened for suitable candidate compounds from methane for self-assembly into membrane-like structures. As per the researchers, the most promising compound they discovered was an acrylonitrile azotosome, which is present in the atmosphere of Titan.
As per the researchers, acrylonitrile has shown good stability and flexibility similar to that of phospholipid membranes on Earth. It means that the Saturn largest has atmosphere and conditions to support life in a different way than earth.
- See more at: http://perfscience.com/content/2141391-life-titan-would-be-different-earth#sthash.2Kqc3Ewf.dpuf

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Strange find on Titan sparks chatter about life

March 2, 2015 / / 0 Comments


Titan


Excerpt from nbcnews.com

Studies may suggest methane-based organic processes ... but maybe not  
New findings have roused a great deal of hoopla over the possibility of life on Saturn's moon Titan, which some news reports have further hyped up as hints of extraterrestrials.
However, scientists also caution that aliens might have nothing to do with these findings.

All this excitement is rooted in analyses of chemical data returned by NASA's Cassini spacecraft. One study suggested that hydrogen was flowing down through Titan's atmosphere and disappearing at the surface. Astrobiologist Chris McKay at NASA's Ames Research Center speculated that this could be a tantalizing hint that hydrogen is getting consumed by life.

"It's the obvious gas for life to consume on Titan, similar to the way we consume oxygen on Earth," McKay said.

Another study investigating hydrocarbons on Titan's surface found a lack of acetylene, a compound that could be consumed as food by life that relies on liquid methane instead of liquid water to live.
"If these signs do turn out to be a sign of life, it would be doubly exciting because it would represent a second form of life independent from water-based life on Earth," McKay said.
However, NASA scientists caution that aliens might not be involved at all.

"Scientific conservatism suggests that a biological explanation should be the last choice after all non-biological explanations are addressed," said Mark Allen, principal investigator with the NASA Astrobiology Institute Titan team. "We have a lot of work to do to rule out possible non-biological explanations. It is more likely that a chemical process, without biology, can explain these results."
McKay told Space.com that "both results are still preliminary."

To date, methane-based life forms are only speculative, with McKay proposing a set of conditions necessary for these kinds of organisms on Titan in 2005. Scientists have not yet detected this form of life anywhere, although there are liquid-water-based microbes on Earth that thrive on methane or produce it as a waste product. 

On Titan, where temperatures are around minus-290 degrees Fahrenheit (-179 degrees Celsius), any organisms would have to use a substance that is liquid as its medium for living processes. Water itself cannot do, because it is frozen solid on Titan's surface. The list of liquid candidates is very short — liquid methane and related molecules such as ethane. Previous studies have found Titan to have lakes of liquid methane.

Missing hydrogen? 

The dearth of hydrogen Cassini detected is consistent with conditions that could produce methane-based life, but do not conclusively prove its existence, cautioned researcher Darrell Strobel, a Cassini interdisciplinary scientist based at Johns Hopkins University in Baltimore. Strobel wrote the paper on hydrogen appearing online in the journal Icarus.

Strobel looked at densities of hydrogen in different parts of the atmosphere and at the surface. Previous models from scientists had predicted that hydrogen molecules, a byproduct of ultraviolet sunlight breaking apart acetylene and methane molecules in the upper atmosphere, should be distributed fairly evenly throughout the atmospheric layers.

Strobel's computer simulations suggest a hydrogen flow down to the surface at a rate of about 10,000 trillion trillion molecules per second. 

"It's as if you have a hose and you're squirting hydrogen onto the ground, but it's disappearing," Strobel said. "I didn't expect this result, because molecular hydrogen is extremely chemically inert in the atmosphere, very light and buoyant. It should 'float' to the top of the atmosphere and escape."

Strobel said it is not likely that hydrogen is being stored in a cave or underground space on Titan. An unknown mineral could be acting as a catalyst on Titan's surface to help convert hydrogen molecules and acetylene back to methane.

Although Allen commended Strobel, he noted "a more sophisticated model might be needed to look into what the flow of hydrogen is."

Consumed acetylene? 

Scientists had expected the sun's interactions with chemicals in the atmosphere to produce acetylene that falls down to coat Titan's surface. But when Cassini mapped hydrocarbons on Titan's surface, it detected no acetylene on the surface, according to findings appearing online in the Journal of Geophysical Research.

Instead of alien life on Titan, Allen said one possibility is that sunlight or cosmic rays are transforming the acetylene in icy aerosols in the atmosphere into more complex molecules that would fall to the ground with no acetylene signature.

In addition, Cassini detected an absence of water ice on Titan's surface, but loads of benzene and another as-yet-unidentified material, which appears to be an organic compound. The researchers said that a film of organic compounds is covering the water ice that makes up Titan's bedrock. This layer of hydrocarbons is at least a few millimeters to centimeters thick, but possibly much deeper in some places. 

"Titan's atmospheric chemistry is cranking out organic compounds that rain down on the surface so fast that even as streams of liquid methane and ethane at the surface wash the organics off, the ice gets quickly covered again," said Roger Clark, a Cassini team scientist based at the U.S. Geological Survey in Denver. "All that implies Titan is a dynamic place where organic chemistry is happening now."

All this speculation "is jumping the gun, in my opinion," Allen said.

"Typically in the search for the existence of life, one looks for the presence of evidence -- say, the methane seen in the atmosphere of Mars, which can't be made by normal photochemical processes," Allen added. "Here we're talking about absence of evidence rather than presence of evidence — missing hydrogen and acetylene — and oftentimes there are many non-life processes that can explain why things are missing."

These findings are "still a long way from evidence of life," McKay said. "But it could be interesting."

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Bees Do It, Humans Do It ~ Bees can experience false memories, scientists say

February 27, 2015 / / 0 Comments



Excerpt from csmonitor.com


Researchers at Queen Mary University of London have found the first evidence of false memories in non-human animals.

It has long been known that humans – even those of us who aren't famous news anchors – tend to recall events that did not actually occur. The same is likely true for mice: In 2013, scientists at MIT induced false memories of trauma in mice, and the following year, they used light to manipulate mice brains to turn painful memories into pleasant ones.

Now, researchers at Queen Mary University of London have shown for the first time that insects, too, can create false memories. Using a classic Pavlovian experiment, co-authors Kathryn Hunt and Lars Chittka determined that bumblebees sometimes combine the details of past memories to form new ones. Their findings were published today in Current Biology.
“I suspect the phenomenon may be widespread in the animal kingdom," Dr. Chittka said in a written statement to the Monitor.
First, Chittka and Dr. Hunt trained their buzzing subjects to expect a reward if they visited two artificial flowers – one solid yellow, the other with black-and-white rings. The order didn’t matter, so long as the bee visited both flowers. In later tests, they would present a choice of the original two flower types, plus one new one. The third type was a combination of the first two, featuring yellow-and-white rings. At first, the bees consistently selected the original two flowers, the ones that offered a reward.

But a good night’s sleep seemed to change all that. One to three days after training, the bees became confused and started incorrectly choosing the yellow-and-white flower (up to fifty percent of the time). They seemed to associate that pattern with a reward, despite having never actually seen it before. In other words, the bumblebees combined the memories of two previous stimuli to generate a new, false memory.

“Bees might, on occasion, form merged memories of flower patterns visited in the past,” Chittka said. “Should a bee unexpectedly encounter real flowers that match these false memories, they might experience a kind of deja-vu and visit these flowers expecting a rich reward.”

Bees have a rather limited brain capacity, Chittka says, so it’s probably useful for them to “economize” by storing generalized memories instead of minute details.

“In bees, for example, the ability to learn more than one flower type is certainly useful,” Chittka said, “as is the ability to extract commonalities of multiple flower patterns. But this very ability might come at the cost of bees merging memories from multiple sequential experiences.”

Chittka has studied memory in bumblebees for two decades. Bees can be raised and kept in a lab setting, so they make excellent long-term test subjects.

“They are [also] exceptionally clever animals that can memorize the colors, patterns, and scents of multiple flower species – as well as navigate efficiently over long distances,” Chittka said.

In past studies, it was assumed that animals that failed to perform learned tasks had either forgotten them or hadn’t really learned them in the first place. Chittka’s research seems to show that animal memory mechanisms are much more elaborate – at least when it comes to bumblebees.

“I think we need to move beyond understanding animal memory as either storing or not storing stimuli or episodes,” Chittka said. “The contents of memory are dynamic. It is clear from studies on human memory that they do not just fade over time, but can also change and integrate with other memories to form new information. The same is likely to be the case in many animals.”

Chittka hopes this study will lead to a greater biological understanding of false memories – in animals and humans alike. He says that false memories aren’t really a “bug in the system,” but a side effect of complex brains that strive to learn the big picture and to prepare for new experiences.

“Errors in human memory range from misremembering minor details of events to generating illusory memories of entire episodes,” Chittka said. “These inaccuracies have wide-ranging implications in crime witness accounts and in the courtroom, but I believe that – like the quirks of information processing that occur in well known optical illusions – they really are the byproduct of otherwise adaptive processes.”

“The ability to memorize the overarching principles of a number of different events might help us respond in previously un-encountered situations,” Chittka added. “But these abilities might come at the expense of remembering every detail correctly.”
So, if generating false memories goes hand in hand with having a nervous system, does all this leave Brian Williams off the hook?

“It is possible that he conflated the memories,” Chittka said, “depending on his individual vulnerability to witnessing a traumatic event, plus a possible susceptibility to false memories – there is substantial inter-person variation with respect to this. It is equally possible that he was just ‘showing off’ when reporting the incident, and is now resorting to a simple lie to try to escape embarrassment. That is impossible for me to diagnose.”

But if Mr. Williams genuinely did misremember his would-be brush with death, Chittka says he shouldn’t be vilified.

“You cannot morally condemn someone for reporting something they think really did happen to them,” Chittka said. “You cannot blame an Alzheimer patient for forgetting to blow out the candle, even if they burn down the house as a result. In the same way, you can't blame someone who misremembers a crime as a result of false memory processes."

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